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Multi-anticoagulant and EDTA dependent pseudothrombocytopenia. Case reports on two pediatric patients

Open Access
|Jun 2014

References

  1. 1. Yoneyama A, Nakahara K. EDTA-dependent pseudothrombocytopenia- differentiation from true thrombocytopenia.
  2. Nihon Rinsho. 2003;61(4):569-74.
  3. 2. Schrezenmeier H, Müller H, Heimpel H, Seifried E.
  4. Anticoagulant-induced pseudothrombocytopenia and pseudoleucocytosis. Thromb Haemost. 1995;73(3):506-13.10.1055/s-0038-1653805
  5. 3. Bizzaro N. EDTA-Dependent Pseudothrombocytopenia: A Clinical and Epidemiological Study of 112
  6. Cases, With 10-Year Follow-Up. Am J Hematol. 1995
  7. Oct;50(2):103-9. DOI: 10.1002/ajh.283050020610.1002/ajh.28305002067572988
  8. 4. Van der Meer W, Allebes W, Simon A, van Berkel Y, de Keijzer MH. Pseudotrombocytopenie: A report of a New Method to Count Platelets in a Person With EDTA-and Temperature-Independent Antibodies of the IgM Type. Eur J Haematol. 2002 Oct;69(4):243-7.10.1034/j.1600-0609.2002.02680.x12431244
  9. DOI: 10.1034/j.1600-0609.2002.02680.x10.1034/j.1600-0609.2002.02680.x
  10. 5. Kabutomori O, Iwatani Y. „Correct” Platelet Count in EDTA-Dependent Pseudothombocytopenia. Eur J Haematol 1995;55(1):67-8. DOI: 10.1111/j.1600-0609.1995.tb00240.x10.1111/j.1600-0609.1995.tb00240.x7615055
  11. 6. Bartels P, Schoorl M, Lombarts A. Screening for EDTA- Dependent Deviations in Platelet Counts and Abnormalities in Platelet Distribution Histograms in Pseudothrombocytopenia.
  12. Scand J Clin Lab Invest. 1997
  13. Nov;57(7):629-36. DOI: 10.3109/0036551970905528710.3109/003655197090552879397495
  14. 7. Lippi G, Plebani M. EDTA-dependent pseudothrombocytopenia: further insights and recommendations for prevention of a clinically threatening artifact. Clin Chem Lab Med. 2012;50(8):1281-5. DOI: 10.1515/ cclm-2012-008110.1515/cclm-2012-008122868791
  15. 8. Podda GM, Pugliano M, Femia EA, Mezzasoma AM, Gresele P, Carpani G, et al. The platelet count in EDTA- anticoagulated blood from patients with thrombocytopenia may be underestimated when measured in routine laboratories. Am J Hematol. 2012 Jul;87(7):727-8.10.1002/ajh.2321622674424
  16. DOI: 10.1002/ajh.2321610.1002/ajh.23216
  17. 9. Chae H, Kim J, Oh EJ, Kim Y, Han K. Novel method to dissociate platelet clumps in ETDA-dependent pseudothrombocytopenia based on the pathophysiological mechanism. Clin Chem Lab Med. 2012 Mar 3;50(8):1387-91. DOI: 10.1515/cclm-2011-089210.1515/cclm-2011-089222868803
  18. 10. Hagerman RS. Ethylenediamenetetraacetic Acid (EDTA)- Dependent Pseudothrombocytopenia: A case report of an Incidental but Important Finding. 2009.
  19. Available from: http://priory.com/med/Case%20Presentation. htm
  20. 11. Saigo K, Sakota Y, Masuda Y. EDTA-dependent pseudothrombocytopenia: clinical aspects and labora tory tests. Rinsho Byori. 2005 Jul;53(7):646-53.
  21. 12. Onder O, Weinstein A, Hoyer LW. Pseudothrombocytopenia caused by platelet agglutinins that are reactive in blood anticoagulated with chelating agents. Blood. 1980 Aug;56(2):177-82.10.1182/blood.V56.2.177.bloodjournal562177
  22. 13. Wu W, Guo Y, Zhang L, Cui W, Li W, Zhang S. Clinical utility of automated platelet clump count in the screening for ethylene diamine tetraacetic acid-dependent pseudothrombocytopenia. Chin Med J (Engl). 2011
  23. Oct;124(20):3353-7.
  24. 14. Yavasoglu I, Acar B, Kadikoylu G, Bolaman Z. Platelet Aggregation Tests Are Affected in Pseudothrombocytopenia.
  25. Lab Med. 2010;41(8):483-5. DOI: 10.1309/ LM9UXAORTFONZ6U5 10.1309/LM9UXAORTFONZ6U5
DOI: https://doi.org/10.2478/rrlm-2014-0017 | Journal eISSN: 2284-5623 | Journal ISSN: 1841-6624
Language: English
Page range: 191 - 198
Submitted on: Jul 17, 2013
Accepted on: Mar 15, 2014
Published on: Jun 21, 2014
Published by: Romanian Association of Laboratory Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year

© 2014 Smaranda Arghirescu, Mihaela Bătăneanț, Cristian Jinca, Andreea Pașcalău, Mihaela Lelik, Mihaela Preja, Ladislau Ritli, E.C. Ursu, Margit Șerban, Hortensia Ioniță, published by Romanian Association of Laboratory Medicine
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.