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Rai stage-related changes within T/NK cell populations from B-CLL patients Cover

Rai stage-related changes within T/NK cell populations from B-CLL patients

Open Access
|Sep 2013

References

  1. 1. Hamblin TJ, Oscier DG, Young BJ. Autoimmunity in chronic lymphocytic leukaemia. J Clin Pathol. 1986;39(7):713-6.10.1136/jcp.39.7.713
  2. 2. Johnston P, Kay N. Pathogenesis of Impaired Cellular Immune Function in CLL. In: Faguet G, editor. Chronic Lymphocytic Leukemia. Contemporary Hematology: Humana Press; 2004. p. 109-21.10.1007/978-1-59259-412-2_5
  3. 3. Vuillier F, Tortevoye P, Binet JL, Dighiero G. CD4, CD8 and NK subsets in B-CLL. Nouv Rev Fr Hematol. 1988;30(5-6):331-4.
  4. 4. Christopoulos P, Pfeifer D, Bartholome K, Follo M, Timmer J, Fisch P, et al. Definition and characterization of the systemic T-cell dysregulation in untreated indolent Bcell lymphoma and very early CLL. Blood. 2011;117(14):3836-46.10.1182/blood-2010-07-299321
  5. 5. Gonzalez-Rodriguez AP, Contesti J, Huergo-Zapico L, Lopez-Soto A, Fernandez-Guizan A, Acebes-Huerta A, et al. Prognostic significance of CD8 and CD4 T cells in chronic lymphocytic leukemia. Leuk Lymphoma. 2010;51(10):1829-36.10.3109/10428194.2010.503820
  6. 6. Catovsky D, Miliani E, Okos A, Galton DA. Clinical significance of T-cells in chronic lymphocytic leukaemia. Lancet. 1974;2(7883):751-2.10.1016/S0140-6736(74)90944-1
  7. 7. Herrmann F, Lochner A, Philippen H, Jauer B, Ruhl H. Imbalance of T cell subpopulations in patients with chronic lymphocytic leukaemia of the B cell type. Clin Exp Immunol. 1982;49(1):157-62.
  8. 8. te Raa GD, Tonino SH, Remmerswaal EB, van Houte AJ, Koene HR, van Oers MH, et al. Chronic lymphocytic leukemia specific T-cell subset alterations are clone-size dependent and not present in monoclonal B lymphocytosis. Leuk Lymphoma. 2012;53(11):2321-5.10.3109/10428194.2012.69827722646856
  9. 9. Mackus WJ, Frakking FN, Grummels A, Gamadia LE, De Bree GJ, Hamann D, et al. Expansion of CMV-specific CD8+CD45RA+CD27- T cells in B-cell chronic lymphocytic leukemia. Blood. 2003;102(3):1057-63.10.1182/blood-2003-01-018212689926
  10. 10. Nunes C, Wong R, Mason M, Fegan C, Man S, Pepper C. Expansion of a CD8(+)PD-1(+) replicative senescence phenotype in early stage CLL patients is associated with inverted CD4:CD8 ratios and disease progression. Clin Cancer Res. 2012;18(3):678-87.10.1158/1078-0432.CCR-11-263022190592
  11. 11. Giannopoulos K, M Schmitt PW, lstrok. The high frequency of T regulatory cells in patients with B-cell chronic lymphocytic leukemia is diminished through treatment with thalidomide. Leukemia. 2007;22(1):222-4.10.1038/sj.leu.240486917657216
  12. 12. D’Arena G, Laurenti L, Minervini MM, Deaglio S, Bonello L, De Martino L, et al. Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease. Leuk Res. 2011;35(3):363-8.10.1016/j.leukres.2010.08.01020880586
  13. 13. Kay NE, Han L, Bone N, Williams G. Interleukin 4 content in chronic lymphocytic leukaemia (CLL) B cells and blood CD8+ T cells from B-CLL patients: impact on clonal B-cell apoptosis. Br J Haematol. 2001;112(3):760-7.10.1046/j.1365-2141.2001.02605.x11260081
  14. 14. Mu X, Kay NE, Gosland MP, Jennings CD. Analysis of blood T-cell cytokine expression in B-chronic lymphocytic leukaemia: evidence for increased levels of cytoplasmic IL-4 in resting and activated CD8 T cells. Br J Haematol. 1997;96(4):733-5.10.1046/j.1365-2141.1997.d01-2107.x9074413
  15. 15. Cyster JG. Chemokines and cell migration in secondary lymphoid organs. Science. 1999;286(5447):2098-102.10.1126/science.286.5447.209810617422
  16. 16. Sallusto F. The role of chemokine receptors in primary, effector and memory immune response. Exp Dermatol. 2002;11(5):476-8.10.1034/j.1600-0625.2002.110514.x
  17. 17. Kim CH, Rott L, Kunkel EJ, Genovese MC, Andrew DP, Wu L, et al. Rules of chemokine receptor association with T cell polarization in vivo. J Clin Invest. 2001;108(9):1331-9.10.1172/JCI1354320944311696578
  18. 18. Fuss IJ, Kanof ME, Smith PD, Zola H. Isolation of whole mononuclear cells from peripheral blood and cord blood. Curr Protoc Immunol. 2009;Chapter 7:Unit7 1.10.1002/0471142735.im0701s8519347849
  19. 19. Ahearne MJ, Willimott S, Pinon L, Kennedy DB, Miall F, Dyer MJ, et al. Enhancement of CD154/IL4 proliferation by the T follicular helper (Tfh) cytokine, IL21 and increased numbers of circulating cells resembling Tfh cells in chronic lymphocytic leukaemia. Br J Haematol. 2013;162(3):360 70.10.1111/bjh.1240123710828
  20. 20. Morita R, Schmitt N, Bentebibel S-E, Ranganathan R, Bourdery L, Zurawski G, et al. Human Blood CXCR5(+) CD4(+) T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion. Immunity. 2011;34(1):108-21.10.1016/j.immuni.2010.12.012304681521215658
  21. 21. Ma J, Zhu C, Ma B, Tian J, Baidoo SE, Mao C, et al. Increased frequency of circulating follicular helper T cells in patients with rheumatoid arthritis. Clin Dev Immunol. 2012;2012:827480.10.1155/2012/827480335793722649468
  22. 22. Lindwall E, Gauthier C, Lyman J, Alarakhia A, Zakem J, Davis W, et al. Circulating T Helper Cells in Patients with Systemic Lupus Erythematosus Share the Phenotypic Property with Lymphoid T Follicular Helper Cells. Nat Immunol. 2010;11(6):464-6.
  23. 23. Li X-y, Wu Z-b, Ding J, Zheng Z-h, Li X-y, Chen Ln, et al. Role of the frequency of blood CD4(+) CXCR5(+) CCR6(+) T cells in autoimmunity in patients with Sjögren’s syndrome. Biochem Biophys Res Commun. 2012;422(2):238-44.10.1016/j.bbrc.2012.04.13322575453
  24. 24. Piper KP, Karanth M, McLarnon A, Kalk E, Khan N, Murray J, et al. Chronic lymphocytic leukaemia cells drive the global CD4+ T cell repertoire towards a regulatory phenotype and leads to the accumulation of CD4+ forkhead box P3+ T cells. Clin Exp Immunol. 2011;166(2):154-63.10.1111/j.1365-2249.2011.04466.x
  25. 25. Junevik K, Werlenius O, Hasselblom S, Jacobsson S, Nilsson-Ehle H, Andersson PO. The expression of NK cell inhibitory receptors on cytotoxic T cells in B-cell chronic lymphocytic leukaemia (B-CLL). Ann Hematol. 2007;86(2):89-94.10.1007/s00277-006-0198-x
  26. 26. Rivino L, Messi M, Jarrossay D, Lanzavecchia A, Sallusto F, Geginat J. Chemokine receptor expression identifies pre-T helper (Th) 1, pre-Th2, and nonpolarized cells among human CD4+ central memory T cells. J Exp Med. 2004;200(6):725-35.10.1084/jem.20040774
  27. 27. Podhorecka M, Dmoszynska A, Rolinski J, Wasik E. T type 1/type 2 subsets balance in B-cell chronic lymphocytic leukemia--the three-color flow cytometry analysis. Leuk Res. 2002;26(7):657-60.10.1016/S0145-2126(01)00194-1
  28. 28. Rossmann ED, Lewin N, Jeddi-Tehrani M, Osterborg A, Mellstedt H. Intracellular T cell cytokines in patients with B cell chronic lymphocytic leukaemia (B-CLL). Eur J Haematol. 2002;68(5):299-306. 10.1034/j.1600-0609.2002.01612.x12144536
DOI: https://doi.org/10.2478/rrlm-2013-0032 | Journal eISSN: 2284-5623 | Journal ISSN: 1841-6624
Language: English
Page range: 321 - 331
Published on: Sep 19, 2013
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2013 Georgiana E. Grigore, Angela Dascalescu, Mihaela Zlei, Iuliu C. Ivanov, Catalin Danaila, Tudor Petreus, Eugen Carasevici, published by Romanian Association of Laboratory Medicine
This work is licensed under the Creative Commons License.

Volume 21 (2013): Issue 3 (September 2013)