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Editorial: Precision medicine in rhinology: Redefining diagnosis and treatment in the era of molecular individualization Cover

Editorial: Precision medicine in rhinology: Redefining diagnosis and treatment in the era of molecular individualization

By: Gabriela Musat  
Open Access
|May 2025

References

  1. Bachert C, Zhang N, Hellings PW, Bousquet J. Endotype-driven care pathways in patients with chronic rhinosinusitis. J Allergy Clin Immunol. 2018;141(5):1543-51. DOI: 10.1016/j.jaci.2018.03.004.
  2. Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, et al. European Position Paper on Rhinosinusitis and Nasal Polyps 2020. Rhinology. 2020;58(Suppl S29):1-464. DOI: 10.4193/Rhin20.600.
  3. Bachert C, Han JK, Desrosiers M, Hellings PW, Amin N, Lee SE, et al. Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicenter, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. Lancet. 2019;394(10209):1638-50. DOI: 10.1016/S0140-6736(19)31881-1.
  4. Gevaert P, Omachi TA, Corren J, Mullol J, Han J, Lee SE, et al. Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials. J Allergy Clin Immunol. 2020;146(3):595-605. DOI: 10.1016/j. jaci.2020.05.032.
  5. Han JK, Bachert C, Fokkens WJ, Desrosiers M, Wagenmann M, Lee SE, et al. Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Respir Med. 2021;9(10):1141-53. DOI: 10.1016/S2213-2600(21)00097-7..
  6. Dzaman K, Rudnicka L, Rykowska A, et al. Challenges in implementing personalized medicine in Central and Eastern Europe. Front Genet. 2020;11:550.
  7. Tait Wojno ED, Monticelli LA. The dynamic nasal immune landscape in chronic rhinosinusitis. Curr Opin Immunol. 2022;74:47-54.
  8. Topol EJ. High-performance medicine: the convergence of human and artificial intelligence. Nat Med. 2019;25(1):44-56. DOI: 10.1038/s41591-018-0300-7.
DOI: https://doi.org/10.2478/rjr-2025-0008 | Journal eISSN: 2393-3356 | Journal ISSN: 2069-6523
Language: English
Page range: 45 - 46
Submitted on: Apr 2, 2025
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Accepted on: Jan 10, 2025
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Published on: May 26, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Gabriela Musat, published by Romanian Rhinologic Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.