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The association of absolute eosinophil count, serum immunoglobulin E and spirometry with co-morbid bronchial asthma in patients with allergic rhinitis Cover

The association of absolute eosinophil count, serum immunoglobulin E and spirometry with co-morbid bronchial asthma in patients with allergic rhinitis

Open Access
|Jul 2019

Abstract

OBJECTIVE. This study aimed to analyse the association of absolute eosinophil count (AEC), serum IgE and spirometry with co-morbid bronchial asthma in patients with allergic rhinitis.

MATERIAL AND METHODS. This study involved 50 patients with signs and symptoms of allergic rhinitis who underwent a clinical examination and various tests, including spirometry, and were followed up regularly. Patients found to have bronchial asthma or nasal polyposis were treated accordingly.

RESULTS. The study found the prevalence of bronchial asthma in patients with allergic rhinitis to be 58% and that the severity of bronchial asthma was reduced significantly, with lesser acute attacks and reduced hospitalizations with the effective treatment of allergic rhinitis (p=0.064).

CONCLUSION. This study showed that elevated AEC and serum IgE were significantly associated with co-existing allergic rhinitis and bronchial asthma and increased the chance of co-existence of these two pathologies. Spirometry is a useful tool for observing the response to treatment.

DOI: https://doi.org/10.2478/rjr-2019-0018 | Journal eISSN: 2393-3356 | Journal ISSN: 2069-6523
Language: English
Page range: 151 - 154
Submitted on: May 4, 2019
Accepted on: Jun 27, 2019
Published on: Jul 30, 2019
Published by: Romanian Rhinologic Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2019 Neelima Vijayan, Padmanabhan Karthikeyan, Nirmal Coumare Venkataramanujam, Ramiya Ramachandran Kaipuzha, Davis Thomas Pulimoottil, published by Romanian Rhinologic Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.