Table 1
Differences in sociodemographic and clinical characteristics of patients
| Variables | All patients | Survive | Exitus | p-value | |
|---|---|---|---|---|---|
| (N=120) | (N=101) | (N=19) | |||
| Age | 66.0 (59.0–71.8) | 66.0 (59.0–71.0) | 68.0 (51.0–70.0) | 0.863 | |
| Gender N (%) | male | 70(58) | 57 (56.4) | 13 (68.4) | 0.448 |
| female | 50(42) | 44 (43.6) | 6 (31.6) | ||
| AVF positioning N (%) | distal | 46(38) | 43 (42.6) | 3 (15.8) | 0.038* |
| proximal | 74(62) | 58 (57.4) | 16 (84.2) | ||
| AVF | 97(81) | 89 (88.2) | 8 (42.1) | ||
| Type of VA N (%) | AVG | 1(1) | 1 (0.9) | 0 (0) | 0.001* |
| Hickman catheter | 22(18) | 11 (10.9) | 11 (57.9) | ||
| Length of HD (months) | 51.0 (29.0–82.8) | 56.0 (32.5–85.0) | 14.0 (6.0–43.0) | 0.001* | |
| Type HD N (%) | bicarbonate | 101(84) | 85 (84.2) | 16 (84.2) | 1.000 |
| hemodiafiltration | 19(16) | 16 (15.8) | 3 (15.8) | ||
| SBP (mmHg) | 30.0 (120.0–140.0) | 130.0 (120.0–140.0) | 120.0 (120.0–140.0) | 0.701 | |
| DBP (mmHg) | 80.0 (70.0–80.0) | 80.0 (70.0–80.0) | 80.00 (70.0–80.0) | 0.409 | |
| BMI (kg/m2) | 24.8 (22.0–27.5) | 24.3 (21.9–27.5) | 25.3 (23.5–27.4) | 0.361 | |
| WBC | 6.4 (5.4–8.0) | 6.2 (5.4–7.9) | 7.2 (5.4–8.5) | 0.411 | |
| HGB | 104.0 (96.3–110.8) | 105.0 (97.5–112.5) | 97.0 (84.0–104.0) | 0.008* | |
| PLT | 94.5 (154.3–244.0) | 191.0 (153.0–237.0) | 225.0 (158.0–280.0) | 0.146 | |
| Urea | 19.7 (17.6–22.8) | 19.6 (17.7–22.8) | 19.7 (17.5–23.0) | 0.776 | |
| Creatinine | 799.5 (683.3–914.0) | 822.0 (687.5–940.5) | 704.0 (637.0–811.0) | 0.042* | |
| Kt/V | 1.1 (0.9–1.2) | 1.1 (1.0–1.2) | 0.9 (0.7–1.2) | 0.010* | |
| Albumin | 40.0 (38.0–42.0) | 40.0 (38.0–42.0) | 39.0 (34.0–42.0) | 0.366 | |
| Prealbumin | 0.3 (0.3–0.4) | 0.3 (0.3–0.4) | 0.3 (0.3–0.4) | 0.729 | |
| Na | 139.0 (137.0–140.3) | 139.0 (138.5–140.5) | 137.0 (136.0–141.0) | 0.404 | |
| K | 5.3 (4.7–5.7) | 5.3 (4.8–5.7) | 4.9 (4.4–5.6) | 0.142 | |
| Ca | 2.3 (2.2–2.4) | 2.3 (2.2–2.4) | 2.2 (2.1–2.4) | 0.212 | |
| P | 1.5 (1.2–1.8) | 1.5 (1.2–1.8) | 1.6 (1.2–2.0) | 0.527 | |
| CRP | 4.1 (1.9–7.6) | 4.2 (1.9–7.6) | 2.9 (2.2–14.1) | 0.404 | |
| β microglobulin | 22.9 (19.2–28.3) | 22.9 (19.4–27.6) | 23.1 (12.6–33.5) | 0.746 | |
| IL-6 | 7.7 (4.6–18.3) | 7.3 (4.6–17.1) | 13.7 (6.9–33.7) | 0.163 | |
| Who created AVF | nephrologist | 29(24) | 25 (24.8) | 4 (21.1) | 1.000 |
| vascular surgeon | 91(76) | 76 (75.2) | 15 (78.9) |
SBP-Systolic blood pressure; DBP-Diastolic blood pressure; BMI-body mass index; VA-Vascular access; AVF-arteriovenous fistula; AVG-arteriovenous graft; WBC-White Blood Cell Count; HGB-Hemoglobin; PLT-Platelet Coun; K-Potassium; Na-Sodium; Ca-Calcium; PO4-Phosphate; CRP-C reactive protein; IL-6-interleukin; Kt/V-HD adequacy index; HD-hemodialysis; CVC-central venous catheter;
Table 2
Results of univariable and multivariable regression of predictors of survival
| Variables | B | Exp(B) | 95% C.I.for EXP(B) | p-value | B | Exp(B) | 95% C.I.for EXP(B) | p-value | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Lower | Upper | Lower | Upper | |||||||
| Age | 0.009 | 1.009 | 0.963 | 1.057 | 0.712 | |||||
| Gender | 0.514 | 1.673 | 0.589 | 4.752 | 0.334 | |||||
| AVF positioning | 1.375 | 3.954 | 1.083 | 14.431 | 0.037* | −0.283 | 0.754 | 0.133 | 4.269 | 0.749 |
| Type of VA | 1.202 | 3.327 | 1.911 | 5.791 | 0.001* | 0.511 | 1.667 | 0.776 | 3.578 | 0.190 |
| Length of HD (months) | −0.041 | 0.960 | 0.936 | 0.984 | 0.001* | −0.035 | 0.966 | 0.936 | 0.996 | 0.028* |
| Type HD | −0.004 | 0.996 | 0.260 | 3.819 | 0.995 | |||||
| SBP (mmHg) | −0.005 | 0.995 | 0.966 | 1.025 | 0.744 | |||||
| DBP (mmHg) | −0.020 | 0.980 | 0.918 | 1.047 | 0.552 | |||||
| BMI (kg/m2) | 0.048 | 1.050 | 0.940 | 1.171 | 0.389 | |||||
| WBC | 0.073 | 1.076 | 0.890 | 1.301 | 0.450 | |||||
| HGB | −0.050 | 0.951 | 0.913 | 0.991 | 0.016* | −0.026 | 0.975 | 0.912 | 1.095 | 0.312 |
| PLT | 0.004 | 1.006 | 0.999 | 1.013 | 0.115 | |||||
| Urea | −0.027 | 0.973 | 0.863 | 1.098 | 0.661 | |||||
| Creatinine | −0.003 | 0.997 | 0.994 | 1.000 | 0.030* | −1.342 | 0.261 | 0.927 | 1.024 | 0.540 |
| Kt/V | −2.209 | 0.110 | 0.012 | 0.997 | 0.050* | −0.950 | 0,387 | 0.035 | 4.278 | 0.438 |
| Albumin | −0.078 | 0.925 | 0.803 | 1.066 | 0.280 | |||||
| Prealbumin | −1.802 | 0.165 | 0.001 | 478.284 | 0.658 | |||||
| Na | −0.210 | 0.811 | 0.517 | 1.271 | 0.360 | |||||
| K | −0.702 | 0.495 | 0.203 | 1.207 | 0.122 | |||||
| Ca | −1.497 | 0.224 | 0.007 | 7.018 | 0.394 | |||||
| P | 0.200 | 1.221 | 0.339 | 4.392 | 0.760 | |||||
| CRP | 0.016 | 1.016 | 0.993 | 1.039 | 0.169 | |||||
| β microglobulin | −0.004 | 0.996 | 0.970 | 1.023 | 0.777 | |||||
| IL-6 | −0.001 | 0.999 | 0.994 | 1.005 | 0.790 | |||||
| Who created AVF | 0.210 | 1.234 | 0.375 | 4.063 | 0.730 | |||||
| Did you start HD with CVC | −0.360 | 0.697 | 0.254 | 1.917 | 0.484 | |||||
VA-Vascular access; SBP-Systolic blood pressure; DBP-Dyastolic blood pressure; BMI-body mass index; AVF-arteriovenous fistula; AVG-arteriovenous graft; WBC-White Blood Cell Count; HGB-Hemoglobin; PLT-Platelet Coun; K-Potassium; Na-Sodium; Ca-Calcium; PO4-Phosphate; CRP-C reactive protein; IL-6-interleukin; Kt/V-HD adequacy index; HD-hemodialysis; CVC-central venous catheter;
Table 3
Results of univariable and multivariable regression of predictors of length of functional vascular access in hemodialysis patients who survived during one-year follow-up
| Variables | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| B (95% C.I. for B) | p-value | B (95% C.I. for B) | p-value | |
| Age | 0.07 (−0.90;1.04) | 0.888 | ||
| Gender | −1.76 (−22.23;18.71) | 0.865 | ||
| AVF positioning | −11.95 (−32.35;8.43) | 0.247 | ||
| Type of vascular access | −13.27 (−29.24;2.68) | 0.102 | ||
| Length of HD (months) | −0.58 (0.47;0.69) | 0.001* | −0.29 (0.14;0.44) | 0.001* |
| Type HD | 23.94 (−3.458;51.33) | 0.086 | ||
| SBP (mmHg) | −0.34 (−0.95;0.27) | 0.269 | ||
| DBP mmHg) | −1.48 (−2.80;–0.13) | 0.032* | 0.30 (−1.08;1.68) | 0.662 |
| BMI (kg/m2) | −1.34 (−3.66;0.98) | 0.254 | ||
| WBC | −4.96 (−8.77;–1.15) | 0.011* | −0.62 (−4.19;2.94) | 0.727 |
| HGB | 1.06 (0.23;1.90) | 0.013* | −0.17 (−0.93;0.59) | 0.654 |
| PLT | −0.22 (−0.37;–0.07) | 0.005* | −0.09 (−0.23;0.05) | 0.197 |
| Urea | −1.30 (−3.25;0.64) | 0.186 | ||
| Creatinine | 0.02 (−0.03;0.07) | 0.357 | ||
| Kt/V | 20.92 (−23.70;65.54) | 0.355 | ||
| Albumin | −1.45 (−4.53;1.63) | 0.352 | ||
| Prealbumin | −51.93 (−180.21;76.34) | 0.421 | ||
| Na | −3.31 (−14.95;8.34) | 0.554 | ||
| K | −2.99 (−17.10;11.12) | 0.674 | ||
| Ca | 40.87 (−18.27;100.02) | 0.172 | ||
| P | 0.16 (−22.94;22.98) | 0.999 | ||
| CRP | −0.31 (−0.90;0.29) | 0.304 | ||
| β microglobulin | 0.10 (−0.19;0.39) | 0.505 | ||
| IL-6 | 0.02 (−0,04; 0.08) | 0.514 | ||
| Who created AVF | −26.24 (−49.03;–3.45) | 0.024* | −23.16 (−42.72; −3.60) | 0.021* |
| Did you start HD with CVK | 25.42 (5.85;44.98) | 0.011* | 7.72 (−9.97;25.72) | 0.381 |
VA-Vascular access; SBP-Systolic blood pressure; DBP-Dyastolic blood pressure; BMI-body mass index; AVF-arteriovenous fistula; AVG-arteriovenous graft; WBC-White Blood Cell Count; HGB-Hemoglobin; PLT-Platelet Coun; K-Potassium; Na-Sodium; Ca-Calcium; PO4-Phosphate; CRP-C reactive protein; IL-6-interleukin; Kt/V-HD adequacy index; HD-hemodialysis; CVC-central venous catheter;