Have a personal or library account? Click to login
The importance of the enzyme Gamma-glutamyltransferase in the pathogenic cluster in type2 diabetic patient Cover

The importance of the enzyme Gamma-glutamyltransferase in the pathogenic cluster in type2 diabetic patient

Open Access
|Feb 2024

References

  1. 1. RADHAKRISHNAN P, SRIKANTH P, SESHADRI KG, BARANI R, SAMANTA M. Serum monocyte chemoattractant protein-1 is a biomarker in patients with diabetes and periodontitis. Indian journal of endocrinology and metabolism. 2014;18(4):505.
  2. ZHAO W, TONG J, LIU J, LIU J, LI J, CAO Y. The dose-response relationship between gamma-glutamyl transferase and risk of diabetes mellitus using publicly available data: a longitudinal study in Japan. International journal of endocrinology. 2020.
  3. KOENIG G, SENEFF S. Gamma-glutamyltransferase: a predictive biomarker of cellular antioxidant inadequacy and disease risk. Disease markers. 2015.
  4. MILLER MC, MAYO KH. Chemokines from a structural perspective. International journal of molecular sciences. 2017;18(10):2088.
  5. VAN COILLIE E, VAN DAMME J, OPDENAKKER G. The MCP/eotaxin subfamily of CC chemokines. Cytokine & growth factor reviews. 1999;10(1):61-86.
  6. KUNKEL SL. Through the looking glass: the diverse in vivo activities of chemokines. The Journal of clinical investigation. 1999;104(10):1333-4.
  7. BRESLIN WL, JOHNSTON CA, STROHACKER K, CARPENTER KC, DAVIDSON TR, MORENO JP, FOREYT JP et al. Obese Mexican American children have elevated MCP-1, TNF-α, monocyte concentration, and dyslipidemia. Pediatrics. 2012;129(5):e1180-6.
  8. BUI TM, WIESOLEK HL, SUMAGIN R. ICAM-1: A master regulator of cellular responses in inflammation, injury resolution, and tumorigenesis. Journal of Leucocyte Biology. 2020;108(3):787-99.
  9. STEINMETZ J, SCHIELE F, GUEGUEN R, FÉRARD G, HENNY J; Periodic Health Examination Centers Laboratory Working Group. Standardization of gamma-glutamyltransferase assays by intermethod calibration. Effect on determining common reference limits. Clin Chem Lab Med. 2007;45(10):1373-80. doi: 10.1515/CCLM.2007.290. PMID: 17924850.
  10. BEUTLER E, Reduced glutathione (GSH), in Red Cell Metabolism, A Manual of Biochemical Methods, E. Beutler and F. L. Orland, Eds., pp. 131–132, Grune&Stratton, New York, NY, USA, 1975.
  11. NAIDU BT, RAJU KS, BHASKARARAO JV, KUMAR NS. Gamma-glutamyl transferase as a diagnostic marker of metabolic syndrome. Cureus. 2023;15(6).
  12. BRADLEY R. Gamma glutamyltransferase (GGT) as a biomarker of atherosclerosis. Biomarkers in cardiovascular disease. Biomarkers in disease: methods, discoveries and applications. Springer, Dordrecht. 2016.
  13. AHN HR, SHIN MH, NAM HS, PARK KS, LEE YH, JEONG SK, CHOI JS et al. The association between liver enzymes and risk of type 2 diabetes: the Namwon study. Diabetology & metabolic syndrome. 2014;6(1):1-8.
  14. NANO J, MUKA T, LIGTHART S, HOFMAN A, DARWISH MURAD S, JANSSEN HL, FRANCO OH et al. Gamma-glutamyltransferase levels, prediabetes and type 2 diabetes: a Mendelian randomization study. International journal of epidemiology. 2017;46(5):1400-7
  15. PENG, JIA, FEI LUO, GUIYUN RUAN, RAN PENG, AND XIANGPING LI. Hypertriglyceridemia and atherosclerosis. Lipids in health and disease 2017;16:1-12.
  16. XUAN, CHAO, JING LI, RU-HUA LIU, JUN-JIE GUO, CONG ZHAO, TING-TING ZHOU, YAN WANG, GUO-WEI HE, AND LI-MIN LUN. Association between serum gamma-glutamyltransferase and early-onset coronary artery disease: a retrospective case-control study. Annals of Medicine. 2023; 55(2):2289606
  17. PAOLICCHI A, EMDIN M, PASSINO C, et al. Lipoprotein and LDL-associated serum γ-glutamyltransferase in patients with coronary atherosclerosis. Atherosclerosis. 2006;186:80–85.
  18. PARK EO, BAE EJ, PARK BH, CHAE SW. The associations between liver enzymes and cardiovascular risk factors in adults with mild dyslipidemia. Journal of clinical medicine. 2020;9(4):1147.
  19. BIN DAHMAN LS, HUMAM MA, BARAHIM OH, BARAHMAN OM, BALFAS MA. Association between Liver Enzymes and Dyslipidemia in Yemeni Patients with Type Two Diabetes Mellitus. Journal of Diabetes Mellitus. 2021;11(02):41-51.
  20. XING Y, CHEN J, LIU J, MA H. Associations between GGT/HDLC and MAFLD: a cross-sectional study. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 2022. 383-94.
  21. GONG S, GAN S, ZHANG Y, ZHOU H, ZHOU Q. Gamma-glutamyl transferase to high-density lipoprotein cholesterol ratio is a more powerful marker than TyG index for predicting metabolic syndrome in patients with type 2 diabetes mellitus. Frontiers in Endocrinology. 2023;14.
  22. CHEN LW, HUANG MS, SHYU YC, CHIEN RN. Gamma‐glutamyl transpeptidase elevation is associated with metabolic syndrome, hepatic steatosis, and fibrosis in patients with nonalcoholic fatty liver disease: A community‐based cross‐sectional study. The Kaohsiung Journal of Medical Sciences. 2021;37(9):819-27.
  23. DILLON JF, MILLER MH. Gamma glutamyl transferase ‘To be or not to be’ a liver function test? Annals of Clinical Biochemistry.2016;53(6):629-631.
  24. JIANG S, JIANG D, TAO Y. Role of gamma-glutamyltransferase in cardiovascular diseases. Experimental & Clinical Cardiology. 2013;18(1):53.
  25. IHM CG, PARK JK, HONG SP, LEE TW, CHO BS, KIM MJ, CHA DR, et al. A high glucose concentration stimulates the expression of monocyte chemotactic peptide 1 in human mesangial cells. Nephron. 1998;79(1):33-7.
  26. KINOSHITA K, TOSHIKUNI N, SAITO T, HAYASHI N, MINATO T, MATSUE Y, UEDA Y et al. The combination of fatty liver and increased gamma-glutamyl transpeptidase levels as a risk factor for atherosclerotic plaque development in apparently healthy people.Turkish Journal of Medical Sciences. 2019;49(5):1350-7
  27. FRANZINI M, CORTI A, MARTINELLI B, et al. Gamma-glutamyltransferase activity in human atherosclerotic plaques – biochemical similarities with the circulating enzyme. Atherosclerosis. 2009;202(1):119–127
  28. MABILE L, RUIDAVETS J-B, FAUVELJ ; PERRET B, FERRIÈRES J, Differential Levels of γ-Glutamyl Transferase Activity and Apolipoprotein CIII in Men on Either Statin or Fibrate Therapy, Diabetes Care 2003;26(5):1652–1653
  29. OUCHI K.W.N., PARKER J.L., LUGUS J.J., WALSH K. Adipokines in inflammation and metabolic disease. Nat. Rev. Immunol. 2011;11:85–97
  30. KATSIKI N, MIKHAILIDIS DP, BANACH M, Leptin, cardiovascular diseases and type 2 diabetes mellitus review-article. Acta Pharmacol. Sin. 2018, 39, 1176–1188
  31. GOYAL R, FAIZY AF, SIDDIQUI SS, SINGHAI M. Evaluation of TNF-α and IL-6 levels in obese and non-obese diabetics: pre-and postinsulin effects. North American journal of medical sciences. 2012;4(4):180.
  32. SHARMA R, SHARMA S, KAUSHIK GG. Gamma-glutamyltransferase (GGT) – a novel marker of endothelial dysfunction. JIACM. 2010;11(1):26–30
  33. ATAY AE, ESEN B, AKBAS H, GOKMEN ES, PILTEN S, GULER H, YAVUZ DG. Polimorfismo 1462A> G (K469E) del gen ICAM-1 y nivel sérico de ICAM-1 en la oligoalbuminuria de pacientes obesos no diabéticos, no hipertensos y normolipidémicos: acervo genético de la oligoalbuminuria en la obesidad. Nefrología (Madrid). 2017;37(4):381-8.
  34. ADAMIEC-MROCZEK J, OFICJALSKA-MŁYŃCZAK J, MISIUK-HOJŁO M. Proliferative diabetic retinopathy—The influence of diabetes control on the activation of the intraocular molecule system. Diabetes research and clinical practice. 2009;84(1):46-50.
  35. BRADLEY R, FITZPATRICK AL, JENNY NS, LEE DH, JACOBS DR Jr. Associations between total serum GGT activity and metabolic risk: MESA. Biomark Med. 2013;7(5):709-21
DOI: https://doi.org/10.2478/rjim-2024-0006 | Journal eISSN: 2501-062X | Journal ISSN: 1220-4749
Language: English
Page range: 203 - 209
Submitted on: Feb 12, 2024
Published on: Feb 20, 2024
Published by: N.G. Lupu Internal Medicine Foundation
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2024 Bogdana Virgolici, Maria Zinaida Dobre, Daniela Lixandru, Laura Petcu, Ariana Picu, Constantin Ionescu-Târgovişte, Maria Greabu, Elena Violeta Bacanu, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.