Have a personal or library account? Click to login
The hidden and complex relationship between dietary phosphorus and malnutrition in hemodialysis patients with chronic kidney disease Cover

The hidden and complex relationship between dietary phosphorus and malnutrition in hemodialysis patients with chronic kidney disease

Open Access
|Mar 2024

Abstract

Introduction:

Chronic kidney disease (CKD) has always been a complicated global challenge, ranking as the 12th leading cause of death worldwide. Hemodialysis, being one of the most opted renal replacement therapies (RRTs) for patients with end-stage renal disease (ESRD), still possesses some limitations in preventing complications, such as malnutrition and mineral bone disease (CKD-MBD). While efforts have focused on controlling CKD-MBD parameters like calcium and phosphate, less attention has been given to dietary interventions. Moreover, the adoption of low-phosphorus diets for hemodialysis patients is very complex due to potential conflicts with the guideline-recommended high-protein dietary approach. This study sought to investigate the relationship between dietary phosphorus intake and nutritional status in CKD patients undergoing regular hemodialysis.

Method:

This non-randomized cross-sectional study comprising 88 patients was conducted at the Hemodialysis Unit, RSUD Dr. Soetomo, Surabaya, East Java, using a three-day dietary record in March 2022. Relationships between variables were analyzed using Spearman and ANOVA tests.

Result:

No significant positive association was found between dietary calcium with corrected calcium levels (p = 0.988; rs = −0.002) and between dietary phosphorus with plasma phosphate levels (p = 0.082; rs = 0.187). However, Spearman's analysis revealed a weak but positive correlation between dietary phosphorus and nutritional status (p = 0.022; rs = 0.215*).

Conclusion:

Our study highlights a positive relationship between dietary phosphorus and nutritional status among hemodialysis patients, offering insights into potential strategies for optimizing patient care and outcomes.

DOI: https://doi.org/10.2478/rjim-2023-0029 | Journal eISSN: 2501-062X | Journal ISSN: 1220-4749
Language: English
Page range: 52 - 60
Submitted on: Aug 29, 2023
Published on: Mar 23, 2024
Published by: N.G. Lupu Internal Medicine Foundation
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2024 Clonia Milla, Widodo, Teddy Heri Wardhana, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.