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The relationship of vitamin D deficiency with severity and outcome of acute stroke Cover

The relationship of vitamin D deficiency with severity and outcome of acute stroke

Open Access
|Nov 2021

References

  1. 1. SACCO RL., KASNER SE., BRODERICK JP., CAPLAN LR., CONNORS JJ., CULEBRAS A., et al. An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke.2013; 44:2064–89.10.1161/STR.0b013e318296aeca23652265
  2. 2. 2MOZAFFARIAN D., BENJAMIN EJ., GO AS., ARNETT DK., BLAHA MJ., CUSHMAN M., et al. Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation.2016;133(4):e38–360.
  3. 3. LADEBY R., WIRENFELDT M, GARCIA-OVEJERO D, FENGER C, DISSING-OLESEN L, DALMAU I, et al. Microglial cell population dynamics in the injured adult central nervous system. Brain Res Brain Res Rev.2005; 48:196–206.10.1016/j.brainresrev.2004.12.00915850658
  4. 4. KENDRICK J, TARGHER G, SMITS G, CHONCHOL M., 25- Hydroxyvitamin D deficiency is independently associated with cardiovascular disease in the Third National Health and Nutrition Examination Survey. Atherosclerosis.2009; 205:255–260.10.1016/j.atherosclerosis.2008.10.03319091317
  5. 5. DURUP D, JØRGENSEN HL, CHRISTENSEN J, TJØNNELAND A, OLSEN A., HALKJÆR J, et al. A Reverse J-Shaped Association Between Serum 25-Hydroxyvitamin D and Cardiovascular Disease Mortality: The CopD Study. J ClinEndocrinolMetab. 2015;100:2339–2346.10.1210/jc.2014-455125710567
  6. 6. TARCIN O., YAVUZ DG., OZBEN B., TELLI A., OGUNC AV., YUKSEL M., TOPRAK A, et al. Effect of Vitamin D Deficiency and Replacement on Endothelial Function in Asymptomatic Subjects. J Clin Endocrinol Metab.2009; 94:4023–4030.10.1210/jc.2008-121219584181
  7. 7. MITRI J., MURARU MD., PITTAS AG., Vitamin D and type 2 diabetes: a systematic review. Eur J Clin Nutr.2011; 65: 1005–1015.10.1038/ejcn.2011.118406638121731035
  8. 8. ZITTERMANN A., GUMMERT JF., BORGERMANN J., The Role of Vitamin D in Dyslipidemia and Cardiovascular Disease. Curr Pharm Des.2011; 17: 933–942.10.2174/13816121179542878621418036
  9. 9. MARTINS D., WOLF M., PAN D., ZADSHIR A., TAREEN N., THADHANI R., et al. Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. Arch Intern Med.2007;167:1159–1165.10.1001/archinte.167.11.115917563024
  10. 10. MARNIEMI J., ALANEN E., IMPIVAARA O., SEPPÄNEN R., HAKALA P., RAJALA T., et al. Dietary and serum vitamins and minerals as predictors of myocardial infarction and stroke in elderly subjects.NutrMetabCardiovasc Dis.2005;15:188–197.10.1016/j.numecd.2005.01.00115955467
  11. 11. SUN Q., PAN A., HU FB., MANSON JE., REXRODE KM.. 25-Hydroxyvitamin D Levels and the Risk of Stroke: A Prospective Study and Meta-analysis.Stroke. 2012; 43(6):1470–7.10.1161/STROKEAHA.111.636910336156222442173
  12. 12. BRØNDUM-JACOBSEN P., NORDESTGAARD BG., SCHNOHR P., BENN M., 25-hydroxyvitamin D and symptomatic ischemic stroke: an original study and meta-analysis. Ann Neurol.2013; 73:38–47.10.1002/ana.2373823225498
  13. 13. CHAUDHURI JR., MRIDULA KR., ALLADI S., ANAMIKA A., UMAMAHESH M., BALARAJU B., et al. Serum 25- hydroxyvitamin d deficiency in ischemic stroke and subtypes in Indian patients. J Stroke.2014;16(1):44–50.10.5853/jos.2014.16.1.44396181824741564
  14. 14. TU W-J., ZHAO S-J., XU D-J., CHEN H., Serum 25-hydroxyvitamin D predicts the short-term outcomes of Chinese patients with acute ischaemic stroke.ClinSci (Lond).2014; 126:339–46.10.1042/CS2013028424020395
  15. 15. TURETSKY A., GODDEAU RP., HENNINGER N. Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke. J Stroke Cerebrovasc Dis.2015; 24:1555–1563.10.1016/j.jstrokecerebrovasdis.2015.03.05126009498
  16. 16. PARK KY., CHUNG PW., KIM YB., MOON HS., SUH BC., WON YS., et al. Serum Vitamin D Status as a Predictor of Prognosis in Patients with Acute Ischemic Stroke. Cerebrovasc Dis.2015; 40:73–80.10.1159/00043469126184826
  17. 17. HOLICK M., Vitamin D deficiency. N Engl J Med.2007; 357:266–81.10.1056/NEJMra07055317634462
  18. 18. EBELING PR., Vitamin D and bone health: Epidemiologic studies. BoneKEy Rep.2014; 3:511.10.1038/bonekey.2014.6401545424818003
  19. 19. COHEN-LAHAV M., SHANY S., TOBVIN D., CHAIMOVITZ C., DOUVDEVANI A., et al. Vitamin D decreases NFkappaB activity by increasing IkappaBalpha levels.Nephrol Dial Transplant.2006; 21:889–97.Epub 2006 Feb 2.10.1093/ndt/gfi25416455676
  20. 20. LIU X., NELSON A., WANG X., FARID M., GUNJI Y., IKARI J, et al. Vitamin D modulates prostaglandin E2 synthesis and degradation in human lung fibroblasts. Am J Respir Cell Mol Biol. 2014; 50:40–50.10.1165/rcmb.2013-0211OC
  21. 21. HUANG Y-N, HO Y-J, LAI C-C, CLIU CT. WANG JY. 1,25-Dihydroxyvitamin D3 attenuates endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation in primary cortical neuron-glia cultures. J Neuroinflammation.2015; 12:147.10.1186/s12974-015-0370-0453225626259787
  22. 22. BOONSTRA A, BARRAT FJ, CRAIN C, HEATH VL, SAVELKOUL HF, O’GARRA A. 1alpha, 25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells. J Immunol. 2001;167:4974–4980.10.4049/jimmunol.167.9.497411673504
  23. 23. MARNIEMI J1, ALANEN E, IMPIVAARA O, SEPPÄNEN R, HAKALA P, RAJALA T, et al. Dietary and serum vitamins and minerals as predictors of myocardial infarction and stroke in elderly subjects.NutrMetabCardiovasc Dis.2005; 15:188–97.
  24. 24. MICHOS ED, REIS JP, POST WS, LUTSEY PL, GOTTESMAN RF, MOSLEY TH, et al. 25-Hydroxyvitamin D deficiency is associated with fatal stroke among whites but not blacks: The NHANES-III linked mortality files. Nutrition.2012;28(4):367–71.10.1016/j.nut.2011.10.015
  25. 25. DAUBAIL B, JACQUIN A, GUILLAND JC, KHOUMRI C, ABOA-EBOULÉ C, GIROUD M, et al. Association between serum concentration of vitamin D and 1-year mortality in stroke patients. Cerebrovasc Dis.2014; 37:364–7.10.1159/000362534
  26. 26. WANG Y, JI H, TONG Y, ZHANG Z. Prognostic Value of Serum 25-Hydroxyvitamin D in Patients with Stroke.Neurochem Res.2014; 39: 1332–1337.10.1007/s11064-014-1316-0
  27. 27. TURETSKY A, GODDEAU RP, HENNINGER N. Low Serum Vitamin D Is Independently Associated with Larger Lesion Volumes after Ischemic Stroke. J Stroke Cerebrovasc Dis.2015; 24:1555–1563.10.1016/j.jstrokecerebrovasdis.2015.03.051
  28. 28. BOLLAND MJ, BACON CJ, HORNE AM, MASON BH, AMES RW, WANG TK, et al. Vitamin D deficiency and health outcomes over 5 y in older women. Am J Clin Nutr.2010; 91: 82–89.10.3945/ajcn.2009.28424
  29. 29. DRECHSLER C, PILZ S, OBERMAYER-PIETSCH B, VERDUIJN M, TOMASCHITZ A, KRANE V, et al. Vitamin D deficiency is associated with sudden cardiac death, combined cardiovascular events, and mortality in haemodialysis patients. Eur Heart J.2010; 31: 2253–2261.10.1093/eurheartj/ehq246
  30. 30. KÜHN T, KAAKS R, TEUCHER B, HIRCHE F, DIERKES J, WEIKERT C, et al. Plasma 25-Hydroxyvitamin D and Its Genetic Determinants in Relation to Incident Myocardial Infarction and Stroke in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Germany Study. PLoS One.2013; 8:1–1210.1371/journal.pone.0069080
  31. 31. GUPTA A, PRABHAKAR S, MODI M, BHADADA SK, LAL V, KHURANA D. Vitamin D status and risk of ischemic stroke in North Indian patients. Indian J EndocrinolMetab2014;18:721–5.doi: 10.4103/2230-8210.139241.10.4103/2230-8210.139241
  32. 32. MAJUMDAR V, PRABHAKAR P, KULKARNI GB, CHRISTOPHER R. Vitamin D status, hypertension and ischemic stroke: a clinical perspective. J Hum Hypertens. 2015;29(11):669–674.10.1038/jhh.2015.10
  33. 33. ODDERSON IR. The National Institutes of Health Stroke Scale and its importance in acute stroke management. Phys Med RehabilClin N Am. 1999; 10(4):787–800, vii.10.1016/S1047-9651(18)30162-1
  34. 34. BANKS JL1, MAROTTA CA. Outcomes validity and reliability of the modified Rankin scale: implications for stroke clinical trials: a literature review and synthesis. Stroke. 2007;38(3):1091–6.10.1161/01.STR.0000258355.23810.c617272767
  35. 35. POOLE KE, LOVERIDGE N, BARKER PJ, HALSALL DJ, ROSE C, REEVE J, et al. Reduced vitamin D in acute stroke. Stroke.2006;37:243–245.10.1161/01.STR.0000195184.24297.c116322500
  36. 36. SUN Q, PAN A, HU FB, MANSON JE, REXRODE KM. 25-Hydroxyvitamin D levels and the risk of stroke: a prospective study and meta-analysis. Stroke.2012;43:1470–1477.10.1161/STROKEAHA.111.636910336156222442173
  37. 37. BUELL JS, DAWSON-HUGHES B, SCOTT TM, WEINER DE, DALLAL GE, QUI WQ, et al. 25 Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services. Neurology.2010;74:18–26.10.1212/WNL.0b013e3181beecb7280902419940273
  38. 38. BONAKDARAN S, VARSTEH AR. Correlation between serum 25-hydroxy vitamin D3 and laboratory risk markers of cardiovascular diseases in type 2 diabetic patients. Saudi Med J. 2009;30:509–514.
  39. 39. CARRELLI AL, WALKER MD, LOWE H, MCMAHON DJ, RUNDEK T, SACCO RL, et al. Vitamin D deficiency is associated with subclinical carotid atherosclerosis: the Northern Manhattan study. Stroke.2011;42:2240–2245.10.1161/STROKEAHA.110.608539314646421719770
  40. 40. MARTINS D, WOLF M, PAN D, ZADSHIR A, TAREEN N, THADHANI R, et al. Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. Arch Intern Med. 2007; 167:1159–1165.10.1001/archinte.167.11.115917563024
  41. 41. ZITTERMANN A, TENDERICH G, BERTHOLD HK, KORFER R, STEHLE P. Low vitamin D status: a contributing factor in the pathogenesis of congestive heart failure? J Am CollCardiol. 2003;41:105–112.
  42. 42. KIM DH, SABOUR S, SAGAR UN, ADAMS S, WHELLAN DJ. Prevalence of hypovitaminosis D in cardiovascular diseases (from the National Health and Nutrition Examination Survey 2001 to 2004). Am J Cardiol. 2008;102:1540–1544.10.1016/j.amjcard.2008.06.06719026311
  43. 43. GIOVANNUCCI E, LIU Y, HOLLIS BW, RIMM EB. 25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med. 2008;168:1174–1180.10.1001/archinte.168.11.1174371939118541825
  44. 44. DE BOER IH, KESTENBAUM B, SHOBEN AB, MICHOS ED, SARNAK MJ, SISCOVICK DS. 25-hydroxyvitamin D levels inversely associated with risk for developing coronary artery calcification. J Am Soc Nephrol.2009;20:1805–1812.10.1681/ASN.2008111157272398319443637
  45. 45. MICHOS ED, MELAMED ML. Vitamin D and cardiovascular disease risk. CurrOpinClinNutrMetab Care. 2008;11:7–12.
  46. 46. MARCÉN R, JIMENEZ S, FERNÁNDEZ-RODRIGUEZ A, GALEANO C, VILLAFRUELA JJ, GOMIS A, et al. Are low levels of 25-hydroxyvitamin D a risk factor for cardiovascular diseases or malignancies in renal transplantation? Nephrol Dial Transplant.2012;27(Suppl 4):iv47–iv52.10.1093/ndt/gfs50823258811
  47. 47. KÜHN T, KAAKS R, TEUCHER B, HIRCHE F, DIERKES J, WEIKERT C, et al. Plasma 25-hydroxyvitamin D and its genetic determinants in relation to incident myocardial infarction and stroke in the European prospective investigation into cancer and nutrition (EPIC)-Germany study. PLoS One.2013;8:e69080.10.1371/journal.pone.0069080
  48. 48. LI YC, KONG J, WEI M, CHEN ZF, LIU SQ, CAO LP. 1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J Clin Invest. 2002;110:229–238.10.1172/JCI0215219
  49. 49. AIHARA K, AZUMA H, AKAIKE M, IKEDA Y, YAMASHITA M, SUDO T, et al. Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice. J Biol Chem. 2004;279:35798–35802.10.1074/jbc.M404865200
  50. 50. WATSON KE, ABROLAT ML, MALONE LL, HOEG JM, DOHERTY T, DETRANO R, et al. Active serum vitamin D levels are inversely correlated with coronary calcification. Circulation. 1997; 96:1755–1760.10.1161/01.CIR.96.6.1755
  51. 51. MERKE J, HOFMANN W, GOLDSCHMIDT D, RITZ E. Demonstration of 1,25(OH)2 vitamin D3 receptors and actions in vascular smooth muscle cells in vitro. Calcif Tissue Int.1987; 41:112–114.10.1007/BF02555253
  52. 52. RIGBY WF, DENOME S, FANGER MW. Regulation of lymphokine production and human T lymphocyte activation by 1, 25-dihydroxyvitamin D3. Specific inhibition at the level of messenger RNA. J Clin Invest.1987;79:1659–1664.10.1172/JCI113004
  53. 53. JOUNI ZE, WINZERLING JJ, MCNAMARA DJ. 1, 25-Dihydroxyvitamin D3-induced HL-60 macrophages: regulation of cholesterol and LDL metabolism. Atherosclerosis.1995; 117:125–138.10.1016/0021-9150(95)05569-I
  54. 54. VILA N, CASTILLO J, DÁVALOS A, CHAMORRO A. Proinflammatory cytokines and early neurological worsening in ischemic stroke. Strok. 2000; 31:2325–2329.10.1161/01.STR.31.10.2325
  55. 55. NEVEU I, NAVEILHAN P, JEHAN F, BAUDET C, WION D, DE LUCA HF, et al. 1,25-dihydroxyvitamin D3 regulates the synthesis of nerve growth factor in primary cultures of glial cells. Brain Res Mol Brain Res.1994; 24:70–6.10.1016/0169-328X(94)90119-8
  56. 56. BALDEN R, SELVAMANI A, SOHRABJI F. Vitamin D deficiency exacerbates experimental stroke injury and dysregulates ischemia-induced inflammation in adult rats. Endocrinology.2012; 153:2420–2435.10.1210/en.2011-1783333963922408173
DOI: https://doi.org/10.2478/rjim-2021-0013 | Journal eISSN: 2501-062X | Journal ISSN: 1220-4749
Language: English
Page range: 351 - 358
Submitted on: Oct 31, 2020
Published on: Nov 20, 2021
Published by: N.G. Lupu Internal Medicine Foundation
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2021 Reza Ebrahimi Rad, Mohammadreza Zarbakhsh, Samira Sarabi, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.