Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) – review

Nicoleta Iftode; Mihaela Andreea Rădulescu; Ștefan Sorin Aramă; Victoria Aramă

doi:10.2478/rjim-2020-0017

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Update on Kaposi sarcoma-associated herpesvirus (KSHV or HHV8) – review

Romanian Journal of Internal Medicine

Volume 58 (2020): Issue 4 (December 2020)

By: Nicoleta Iftode, Mihaela Andreea Rădulescu, Ștefan Sorin Aramă and Victoria Aramă

Open Access

|Dec 2020

Abstract

Human herpesvirus 8 (HHV8), also known as Kaposi sarcoma-associated herpesvirus (KSHV), is one of the few pathogens recognized as direct carcinogen, being involved in the pathogenesis of Kaposi sarcoma, primary effusion lymphoma and multicentric Castleman disease. KSHV is a relatively recently discovered virus, with still limited possibilities for diagnosis and treatment. Therefore, ongoing studies are trying to answer the main issues related to the management of KSHV infection and its associated diseases. This review updates the current knowledge of the KSHV infection, discussing aspects related to epidemiology, virological features, clinical manifestations, diagnosis and treatment.

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Articles in this issue

DOI: https://doi.org/10.2478/rjim-2020-0017 | Journal eISSN: 2501-062X | Journal ISSN: 1220-4749

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Language: English

Page range: 199 - 208

Submitted on: Jun 10, 2020

Published on: Dec 17, 2020

Published by: N.G. Lupu Internal Medicine Foundation

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

Kaposi sarcoma-associated herpesvirus,

KSHV,

Kaposi sarcoma,

primary effusion lymphoma,

multicentric Castleman disease

Related subjects:

Medicine,

Clinical medicine,

Internal medicine,

Internal medicine, other,

Cardiology,

Gastroenterology,

Rheumatology

© 2020 Nicoleta Iftode, Mihaela Andreea Rădulescu, Ștefan Sorin Aramă, Victoria Aramă, published by N.G. Lupu Internal Medicine Foundation
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 58 (2020): Issue 4 (December 2020)