Epidural Analgesia for Labour: Comparing the Effects of Continuous Epidural Infusion (CEI) and Programmed Intermittent Epidural Bolus (PIEB) on Obstetric Outcomes

		CEI	PIEB	Total	P Value-Chi Square test
N (%)		1387 (51.4%)	1309 (48.6%)	2696 (100%)
Number of Births	Nulliparous	406 (29.3%)	383 (29.3%)	789 (29.3%)	0.994
Multiparous	981 (70.7%	926 (70.7%)	1907 (70.7%)

Type of Delivery	NVD	1211 (87.3%)	1162 (88.8%)	2373 (88.0%)	0.44
Type of Delivery	Vacuum	116 (8.4%)	101 (7.7%)	217 (8.0%)
CS	60 (4.3%)	46 (3.5%)	106 (3.9%)
Initiation of Delivery	Spontaneous	1171 (84.4%)	1115 (85.2%)	2286 (84.8%)	0.586
Augmentation	216 (15.6%)	194 (14.8%)	410 (15.2%)
Birth Weight	BW<4 kg	1299 (93.7%)	1224 (93.5%)	2523 (93.6%)	0.875
BW>=4 kg	88 (6.3%)	85 (6.5%)	173 (6.4%)
Any past CS	No	1278 (92.1%)	1193 (91.1%)	2471 (91.7%)	0.347
Yes	109 (7.9%)	116 (8.9%)	225 (8.3%)
APGAR 1	Apgar<=7	52 (3.7%)	35 (2.7%)	87 (3.2)	0.114
Apgar>8	1335 (96.3%)	1274 (97.3%)	2609 (96.8%)
APGAR 5	Apgar<=7	15 (1.1%)	8 (0.6%)	23 (0.9%)	0.184
Apgar>8	1372 (98.9%)	1301 (99.4%)	2673 (99.1%)

Table 2

Descriptive Statistics of Maternal, Labour and Newborn Characteristics

	Age	Gravity	Parity	Gestational age (weeks)	Birth Weight	1^st Stage of labor (hours)	2^nd Stage of labor (hours)
Mean	29.02	3.65	3.22	39.36	3322	8.6	0.75
Median	28	3	2	40	3330	7.4	0.3
Std. Deviation	5.66	2.8	2.4	1.59	464.64	5.99	0.95

Table 3

Descriptive Statistics of Maternal, Labour and Newborn Characteristics by Groups (CEI / PIEB)

	Study Group	Mean	Std. Deviation	Std. Error Mean	Sig. (2-tailed)
Age	CEI	29.0	5.61	0.15	0.97
PIEB	29.0	5.73	0.16
Gravity	CEI	3.7	2.82	0.08	0.79
PIEB	3.6	2.79	0.08
Parity	CEI	3.2	2.45	0.07	0.59
PIEB	3.2	2.36	0.07
Gestational age	CEI	39.4	1.46	0.04	0.06
PIEB	39.3	1.71	0.05
Birth Weight	CEI	3326.7	452.2	12.14	0.62
PIEB	3317.8	477.6	13.21
1^st Stage of labour (hours)	CEI	8.8	6.33	0.18	0.13
PIEB	8.4	5.61	0.17
2^nd Stage of labour (hours)	CEI	0.8	0.96	0.03	0.91
PIEB	0.7	0.93	0.03

Table 4

Mode of Delivery Depending on the Method of Epidural Analgesia Administration, Segmented to Nulliparous and Multiparous Parturients

		NVD	Vacuum	CS	Total	P Value-Chi Square test
Nulliparous	CEI	292 (71.9%)	81 (20%)	33 (8.1%)	406	0.192
PIEB	295 (77%)	58 (15.1%)	30 (7.8%)	383
Multiparous	CEI	919 (93.7%)	35 (3.6%)	27 (2.8%)	981	0.168
PIEB	867 (93.6%)	43 (4.6%)	16 (1.7%)	926

Table 5

Duration of the First and Second Stages of Labour Depending on the Method of Epidural Analgesia Administration, Segmented to Nulliparous and Multiparous Parturients

			N	Mean (hours)	Std. Deviation	p-value (t-test)
Nulliparous	1^st stage of labour	CEI	334	10.84	6.03	0.64
	PIEB	323	10.62	6.04
	2^nd stage of labour	CEI	376	1.75	1.09	0.24
PIEB	360	1.66	1.06
Multiparous	1^st Stage of labour	CEI	853	7.98	6.26	0.12
	PIEB	826	7.54	5.18
	2^nd Stage of labour	CEI	944	0.35	0.52	0.22
PIEB	903	0.38	0.55

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DOI: https://doi.org/10.2478/rjaic-2021-0005 | Journal eISSN: 2502-0307 | Journal ISSN: 2392-7518

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Language: English

Page range: 29 - 35

Published on: Sep 25, 2022

Published by: Sciendo

In partnership with: Paradigm Publishing Services

Keywords:

Epidural anaesthesia,

labour analgesia,

continuous epidural infusion,

programmed intermittent epidural bolus analgesia

Related subjects:

Medicine,

Clinical medicine,

Clinical medicine, other,

Surgery,

Surgery, other,

Anaesthesiology,

Emergency medicine and intensive-care medicine

© 2022 Tal Avraham, Yair Binyamin, Sophie Benamram, Daniel Ioscovich, Reut Rotem, Sorina Grisaru-Granovsky, Alexander Ioscovich, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 28 (2021): Issue 1 (July 2021)