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Antiemetic Efficacy of Palonosetron Compared with the Combination of Ondansetron and Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Gynaecological Surgery Cover

Antiemetic Efficacy of Palonosetron Compared with the Combination of Ondansetron and Dexamethasone for Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Gynaecological Surgery

Open Access
|Sep 2022

Figures & Tables

Need for Rescue antiemetic in both the groups

Rescue antiemeticGroup 1Group 2P value
Yes8 (19.05%)0 (0%)0.0093
No34 (80.95%)42 (100%)
Total4242

Distribution of proposed procedures

Proposed procedureGroup 1Group 2Grand TotalP value
DHL (Diagnostic Hystero laparoscopy)3032620.193
Laparoscopic Cystectomy7714
Laparoscopic Hysterectomy1 1
Laparoscopic Tubal Occlusion325
Laparoscopy1 1
Total Laparoscopic Hysterectomy 11
Total424284

Comparison of the Apfel scores between the groups

Apfel ScoreGroup 1Group 2TotalP value
23173.80%3276.19%630.992
31126.20%1023.81%21
Total42100.00%42100.00%84

Comparison of two groups in terms of PONV incidence

PONV IncidenceGroup 1Group 2P value


NauseaVomitingTotal PONVNauseaVomitingTotal PONV
At 1 hour0000001.000
At 4 hr1 (2.38%)1 (2.38%)2 (4.76%)0000.1548
At 8 hr1 (2.38%)1 (2.38%)2 (4.76%)0000.1548
At 24 hr4 (9.52%)04 (9.52%)0000.0416#
At 24–48 hr2 (4.76%)02 (4.76%)2 (4.76%)1 (2.38%)3 (7.14%)0.6312
Total8 (19.05%)2 (4.76%)10 (23.81%)2 (4.76%)1 (2.38%)3 (7.14%)0.0488
DOI: https://doi.org/10.2478/rjaic-2021-0003 | Journal eISSN: 2502-0307 | Journal ISSN: 2392-7518
Language: English
Page range: 19 - 24
Published on: Sep 25, 2022
Published by: Sciendo
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2022 Samarjit Dey, Sairem Mangolnganbi Chanu, Priyanka Dev, Manas Borthakur, Habib Md Reazaul Karim, Md Yunus, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.