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Comparison of Goal-Directed Fluid Therapy Using LiDCOrapid System with Regular Fluid Therapy in Patients Undergoing Spine Surgery as a Randomised Clinical Trial Cover

Comparison of Goal-Directed Fluid Therapy Using LiDCOrapid System with Regular Fluid Therapy in Patients Undergoing Spine Surgery as a Randomised Clinical Trial

Open Access
|Sep 2022

Figures & Tables

Figure 1

CONSORT flow diagram showing the flow of patients through each stage of study.
CONSORT flow diagram showing the flow of patients through each stage of study.

Figure 2

Intraoperative protocol of GDFT in LiDCO group. SVV, stroke volume variation; CO, cardiac output; CI, cardiac index; SV, stroke volume. *If volume loss due to bleeding reaches maximum allowable blood loss (MABL) fluid challange will be stopped and fluid therabhy will be continued with blood transfusion.
Intraoperative protocol of GDFT in LiDCO group. SVV, stroke volume variation; CO, cardiac output; CI, cardiac index; SV, stroke volume. *If volume loss due to bleeding reaches maximum allowable blood loss (MABL) fluid challange will be stopped and fluid therabhy will be continued with blood transfusion.

Figure 3

Base deficit (meq/l) values in two groups.
Base deficit (meq/l) values in two groups.

Figure 4

Comparison of injected crystalloid volume urinary and output in two groups.
Comparison of injected crystalloid volume urinary and output in two groups.

Comparison of peri- and postsurgical complications in two groups of patients

GroupControl N (%)LiDCO-Rapid N (%)Total N (%)Probability
Blood transfusion2 (10)3 (15)5 (12.5)0.633
Myocardial infarction0 (0)0(0)0 (0)-
Stroke0 (0)0 (0)0 (0)-
Pulmonary thromboembolism0 (0)0(0)0 (0)-
Deep vein thrombosis1 (5)0(0)1 (2.5)0.3
Pneumonia1 (5)1(5)2 (5)0.100
Pulmonary edema0 (0)0 (0)0 (0)-
Urinary tract infection0 (0)0(0)0 (0)0.1000
Sepsis0 (0)0 (0)0 (0)-
Acute respiratory distress syndrome0 (0)0 (0)0 (0)-
Acute renal failure0 (0)0 (0)0 (0)-
Postsurgical nausea and vomiting6 (30)3 (15)9 (22.5)0.256
Reintubation0 (0)0 (0)0 (0)-
Lower extremity nerve defect0 (0)0 (0)0 (0)-
Total complications11 (55)6 (30)17 (42.5)0.110

Comparing the peri- and postsurgical quantitative variables in two groups

GroupNMeanStandard deviationMedianIQRProbability
Bleeding (cc)control20527.00273.90--0.916
LiDCO20517.50290.47--
Base excess (mEq/L)control20−8.251.94--<0.001
LiDCO20−4.752.22--
Volume (cc) crystalloidcontrol201920.00584.53--0.001
LiDCO201332.50409.19--
Urine output (cc)control20647.50211.18--<0.001
LiDCO20377.50105.72--
Hospitalization (day)control20--22–30.027*
LiDCO20--21–2
ICU admission (day)control10--0.50–10.087*
LiDCO6--00–0.75
Starting solids (hour)control20--108–12<0.001*
LiDCO20--76–7.5

Preoperative characteristics of patients divided into two groups

GroupControl N (%)LiDCO-Rapid N (%)Total N (%)Probability
SexFemale11 (55)11(55)22 (55)0.624
Male9 (45)9 (45)18 (45)
ASAI5 (25)6 (30)11 (27.5)0.500
II15 (75)14 (70)29 (72.5)
Hypertension10 (50)6 (30)16 (40)0.167
Hyperlipidemia2 (10)0 (0)2 (5)0.244
Diabetes mellitus5 (25)2 (10)7 (17.5)0.204
Ischemic heart disease4 (20)3 (15)7 (17.5)0.500
Mitral valve prolapse0 (0)1 (5)1 (2.5)0.500
Chronic obstructive pulmonary disease1 (5)1(5)2(5)1.000
DOI: https://doi.org/10.2478/rjaic-2021-0001 | Journal eISSN: 2502-0307 | Journal ISSN: 2392-7518
Language: English
Page range: 1 - 9
Published on: Sep 25, 2022
Published by: Sciendo
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2022 Reza Shariat Moharari, Shervin Shahinpour, Farhad Etezadi, Atabak Najafi, Mohammad Reza Khajavi, Pejman Pourfakhr, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.