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Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: a single-institution experience Cover

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: a single-institution experience

By:  and    
Open Access
|Sep 2026

Figures & Tables

TABLE 1.

Patients and tumor characteristics

N (%)
Sex
 Male28 (56)
 Female22 (44)
Mean age, years (range)54 (28-73)
Diagnosis of peritoneal metastases (PM)
 Synchronous to primary tumour22 (44)
 Metachronous to primary tumour28 (56)
Systemic chemotherapy
 No chemotherapy4 (8)
 Preoperative28 (56)
 Postoperative35 (70)
 Both17 (34)
Peritoneal Cancer Index (PCI)
 Mean (range)8.33 (1–35)
 0–831 (62)
 9–129 (18)
 13–3910 (20)
Complete cytoreduction (CC-0/1)44 (88)
Prior surgery score (PSS)
 033 (66)
 16 (12)
 29 (18)
 32 (4)
Median duration of hospital stay, days (range)15 (6–114)
Clavien-Dindo III/IV9 (18)
FIGURE 1.

Kaplan-Meier curve: overall survival in our patient sample.

TABLE 2.

Univariate analysis, parameters affecting overall survival

P
SexNot significant (NS)
AgeNS
Diagnosis of peritoneal metastases (PM)NS
Systemic chemotherapyNS
Peritoneal Cancer Index (PCI) score0.001
Completeness of cytoreduction0.042
Prior surgery score (PSS) score0.006
FIGURE 2.

Kaplan-Meier curves: overall survival according to Peritoneal Cancer Index (PCI) score category.+

TABLE 3.

Overall survival (OS) analysis according to Peritoneal Cancer Index (PCI) category

PCI score categoryNumber of patientsOS (median)p
0–831630.014
9–12957
13–391024
TABLE 4.

Multivariate analysis, independent prognostic factors of overall survival

P
SexNot significant (NS)
AgeNS
Diagnosis of peritoneal metastases (PM)NS
Systemic chemotherapyNS
Peritoneal Cancer Index (PCI) score0.009
Completeness of cytoreduction0.031
Prior surgery score (PSS) scoreNS
DOI: https://doi.org/10.2478/raon-2026-0041 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 436 - 441
Submitted on: Mar 22, 2026
Accepted on: May 28, 2026
Published on: Sep 7, 2026
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Gasper Pilko, Rok Petric, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution 4.0 License.