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Efficacy and safety of percutaneous microwave ablation for liver tumors using an antenna with anti-phase technology offering ultraspherical ablation Cover

Efficacy and safety of percutaneous microwave ablation for liver tumors using an antenna with anti-phase technology offering ultraspherical ablation

Open Access
|Dec 2025

Figures & Tables

FIGURE 1.

Flowchart of the patients.
Flowchart of the patients.

FIGURE 2.

(A-D) Radiological findings in a 48-year-old woman with ductal breast carcinoma. PET-CT revealed a hypermetabolic metastasis in segment 6, (A) (white arrow). Ultrasound showed a subcapsular hypoechoic lesion (B), which was treated with percutaneous microwave ablation under ultrasound guidance. Follow-up CT one day after ablation demonstrated a lesion/ablation area ratio of 1.6 without contrast enhancement, (C) (black arrow). PET-CT at 36 months showed no pathological FDG uptake in the liver (D).
(A-D) Radiological findings in a 48-year-old woman with ductal breast carcinoma. PET-CT revealed a hypermetabolic metastasis in segment 6, (A) (white arrow). Ultrasound showed a subcapsular hypoechoic lesion (B), which was treated with percutaneous microwave ablation under ultrasound guidance. Follow-up CT one day after ablation demonstrated a lesion/ablation area ratio of 1.6 without contrast enhancement, (C) (black arrow). PET-CT at 36 months showed no pathological FDG uptake in the liver (D).

FIGURE 3.

Analysis of disease-free survival (DFS) in patients who underwent microwave ablation (MWA).
Analysis of disease-free survival (DFS) in patients who underwent microwave ablation (MWA).

Inclusion and exclusion criteria of the study

IncludedExcluded
Lesions not amenable to surgical treatmentPresence of extrahepatic metastases
Insufficient functional liver capacity after surgerySuspected pregnancy
Patients unable to undergo general anesthesia due to comorbiditiesUncorrectable coagulopathy
Cases with the use of the particular antenna technologyAny other transarterial or percutaneous treatment

Primary tumors of patients who underwent ablation due to liver metastasis

n%
Colorectal
 Colon3238.5
 Rectum1416.9
Non-colorectal
 Breast1416.9
 Gastric89.6
 Pancreas56
 Ova rian56
 Lung33.6
 Endometrium22.5

Univariate analysis of factors associated with local tumor progression in MWA-treated patients

Variablesp
Sex (male vs. female)0.372
Age (≤ 65 vs. > 65 years)0.415
White blood cell count (≤8 ×103/L vs. > 8 ×103/L)0.554
Neutrophil-to-lymphocyte ratio (≤2 vs. > 2)0.297
Primary tumor (HCC vs. metastasis)0.624
Metastasis type (colorectal vs. non-colorectal)0.198
Tumor location (favorable vs. unfavorable)0.339
Tumor size (≤3 cm vs. > 3 cm)0.012

Clinical and demographic characteristics of the patients

n
Sex (female/male)49 (53.3%)/43 (46.7%)
Age59.8 ± 12.3
Age group (≤ 65/> 65 years)60 (65.2%)/32 (34.8%)
White blood cell count6.5 ± 2.4 ×103/L
White blood cell count group (≤ 8 ×103 /L / > 8 ×103/L)70 (76.1%)/22 (23.9%)
Neutrophil-to-lymphocyte ratio2.6 (range: 1-10.4)
Neutrophil-to-lymphocyte ratio group (≤ 2 / > 2)23 (25%)/69 (75%)
Tumor location (favorable/unfavorable)109 (81.9%)/24 (18.1%)
Tumor size26.1 ± 13.4 mm
Tumor size group (≤ 3 cm / >3 cm)93 (69.9%)/40 (30.1%)
DOI: https://doi.org/10.2478/raon-2025-0064 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 526 - 534
Submitted on: Apr 24, 2025
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Accepted on: Nov 1, 2025
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Published on: Dec 16, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Erbil Arik, Onur Taydas, Tunahan Dertli, Omer Faruk Sevinc, Ahmet Burak Kara, Omer Faruk Topaloglu, Mustafa Ozdemir, Adem Senturk, Alp Omer Canturk, Ilhan Hacibekiroglu, Mehmet Halil Ozturk, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution 4.0 License.