Susceptibility among patients colonized by potentially pathogenic microorganisms (PPMs)
| Amoxicillin with clavulanic acid | First generation cephalosporin | Total | ||
|---|---|---|---|---|
| R | S | S/R | ||
| R | 1 | 1 | 0 | 2 |
| S | 1 | 20 | 0 | 21 |
| S/R | 0 | 5 | 3 | 8 |
| Total | 2 | 26 | 3 | 31 |
Susceptibility among all colonized patients
| Amoxicillin with clavulanic acid | First generation cephalosporin | Total | ||
|---|---|---|---|---|
| R | S | S/R | ||
| R | 2 | 2 | 0 | 4 |
| S | 2 | 101 | 1 | 104 |
| S/R | 0 | 6 | 6 | 12 |
| Total | 4 | 109 | 7 | 120 |
Number and percentage of recovered bacteria
| RECOVERED BACTERIA | No. of patients with isolated species | % of patients with isolated species |
|---|---|---|
| Streptococcus mitis | 53 | 35,6% |
| Streptococcus salivarius | 36 | 24,2% |
| Streptococcus oralis | 27 | 18,1% |
| Streptococcus parasanguinis | 23 | 15,4% |
| Streptococcus vestibularis | 18 | 12,1% |
| Veillonella atypica | 13 | 8,7% |
| Haemophilus influenzae | 12 | 8,1% |
| Streptococcus pneumoniae | 11 | 7,4% |
| Neisseria subflava | 9 | 6,0% |
| Actinomyces odontolyticus | 9 | 6,0% |
| Staphylococcus aureus | 8 | 5,4% |
| Haemophilus parahaemolyticus | 8 | 5,4% |
| Streptococcus gordonii | 8 | 5,4% |
| Rothia mucilaginosa | 7 | 4,7% |
| Escherichia coli | 6 | 4,0% |
| Staphylococcus epidermidis | 6 | 4,0% |
| Staphylococcus hominis | 4 | 2,7% |
| Streptococcus anginosus | 4 | 2,7% |
| Veillonella parvula | 3 | 2,0% |
| Fusobacterium periodonticum | 3 | 2,0% |
| Moraxella catarrhalis | 2 | 1,3% |
| Pseudomonas aeruginosa | 2 | 1,3% |
| Haemophilus parainfluenzae | 2 | 1,3% |
| Corynebacterium simulans | 2 | 1,3% |
| Prevotella nigrescens | 2 | 1,3% |
| Streptococcus constellatus | 2 | 1,3% |
| Gemella haemolysans | 2 | 1,3% |
| Serratia marcescens | 2 | 1,3% |
| Prevotella melaninogenica | 2 | 1,3% |
| Granulicatella adiacens | 2 | 1,3% |
| Streptococcus agalactiae | 1 | 0,7% |
| Staphylococcus capitis | 1 | 0,7% |
| Streptococcus cristatus | 1 | 0,7% |
| Neisseria macacae | 1 | 0,7% |
| Neisseria cinerea | 1 | 0,7% |
| Neisseria flavescens | 1 | 0,7% |
| Veillonella dispar | 1 | 0,7% |
| Prevotella jejuni | 1 | 0,7% |
| Campylobacter concisus | 1 | 0,7% |
| Citrobacter koseri | 1 | 0,7% |
| Prevotella pallens | 1 | 0,7% |
| Enterobacter bugandensis | 1 | 0,7% |
| Acinetobacter lwoffii | 1 | 0,7% |
| Moraxella nonliquefaciens | 1 | 0,7% |
Relationship between colonization with potentially pathogeni microorganisms (PPMs) and chronic obstructive pulmonary disease (COPD)
| COPD | PPMs | Total | |
|---|---|---|---|
| no | yes | ||
| no | 83 | 21 | 104 |
| 79.8% | 20.2% | 100.0% | |
| yes | 32 | 12 | 44 |
| 72.7% | 27.3% | 100.0% | |
| Total | 115 | 33 | 148* |
| 77.7% | 22.3% | 100.0% | |
Baseline characteristics of patients
| Characteristics | n | % |
|---|---|---|
| Patients | 149 | |
| Male | 90 | 60.4 |
| Median age (years) | 66 | |
| Smokers | 50 | 33.6 |
| Ex-smokers | 71 | 47,7 |
| Non-smokers | 28 | 18,8 |
| COPD | 44 | 29.5 |
| Diabetes type 2 | 13 | 8.7 |
| Colonized patients | 132 | 88.6 |
| Colonized with PPMs | 32 | 21.5 |
| Multiple bacteria colonization | 86 | 57.7 |
| Adenocarcinoma | 86 | 57.7 |
| Squamous cell carcinoma | 22 | 14.8 |
| Small cell carcinoma, carcinoid or large cell carcinoma | 11 | 7.4 |
| Non-small cell carcinoma NOS* | 17 | 11.4 |
| Other, non-lung cancer malignancies (limfoma, methastases) | 13 | 8,7 |
Relationship between colonization with potentially pathogenic microorganisms (PPMs) and diabetes type 2
| DIABETES TYPE 2 | PPMs | Total | |
|---|---|---|---|
| no | yes | ||
| no | 108 | 27 | 135 |
| 80.0% | 20.0% | 100.0% | |
| yes | 7 | 6 | 13 |
| 53.8% | 46.2% | 100.0% | |
| Total | 115 | 33 | 148* |
| 77.7% | 22.3% | 100.0% | |
Relationship between cancer stage and colonization with potentially pathogenic microorganisms (PPMs)
| STAGE (8th TNM classification) | PPMs | Total | |
|---|---|---|---|
| no | yes | ||
| I | 50 | 11 | 61 |
| 82.0% | 18.0% | 100.0% | |
| II | 25 | 7 | 32 |
| 78.1% | 21.9% | 100.0% | |
| III | 16 | 6 | 22 |
| 72.7% | 27.3% | 100.0% | |
| IV | 11 | 2 | 13 |
| 84.6% | 15.4% | 100.0% | |
| Total | 102 | 26 | 128* |
| 79.7% | 20.3% | 100.0% | |