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Effectiveness of tramadol or topic lidocaine compared to epidural or opioid analgesia on postoperative analgesia in laparoscopic colorectal tumor resection Cover

Effectiveness of tramadol or topic lidocaine compared to epidural or opioid analgesia on postoperative analgesia in laparoscopic colorectal tumor resection

Open Access
|Jan 2025

Figures & Tables

FIGURE 1.

Consort chart of the study. Thet diagram shows the flow of participants through each stage of a randomized trial. PCA = patient-controlled analgesia; PCEA = patient-controlled epidural analgesia

FIGURE 2.

Piritramide consumption on day of surgery (day 0).

FIGURE 3.

Piritramide consumption on first postoperative day (day 1). PCA = patient-controlled analgesia; PCEA = patient-controlled epidural analgesia

FIGURE 4.

Piritramide consumption on second postoperative day (day 2). PCA = patient-controlled analgesia; PCEA = patient-controlled epidural analgesia

Comparison of piritramide consumption between the group pairs

Comparison P value (day 0)P value (day 1)P value (day 2)
PCAPCEA0.938< 0.001< 0.001
PCAtramadol-metamizole0.083< 0.001< 0.001
PCAPCA + lidocaine0.9950.0030.026
PCEAtramadol-metamizole0.0080.3520.038
PCEAPCA + lidocaine0.862< 0.001< 0.001
PCA + lidocainetramadol-metamizole0.030< 0.001< 0.001

The scores from Pain Detect and DN4 (Douleur Neuropathique 4) questionnaires in the study groups

Group (No. of answers)Pain score (mean ± SD)DN4 (mean ± SD)
PCA (12)00
Tramadol and metamizole (12)1.2 ±2.10.2 ± 0.4
PCEA (15)0.1 ± 0.50.1 ± 0.4
Lidocaine (17)0.06 ± 0.20

General patients’ and procedure characteristics

Group 1 (PCA)Group 2 (tramadol-metamizole)Group 3 (PCEA)Group 4 (PCA and lidocaine)p
Age (years)596560590,394
Weight (kg)767579760,833
Wound length (cm)6,557,177,457,900,286
Duration of surgery (min)1391331171120,024
Duration of hospitalization (days)898100,380
Day of first defecation44540,571
DOI: https://doi.org/10.2478/raon-2025-0003 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 132 - 138
Submitted on: Jun 18, 2024
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Accepted on: Oct 24, 2024
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Published on: Jan 4, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2025 Alenka Spindler-Vesel, Matej Jenko, Ajsa Repar, Iztok Potocnik, Jasmina Markovic-Bozic, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution 4.0 License.