FIGURE 1.
FIGURE 2.
Comparison of time-based patient groups for learning curve estimation on institution level
| Targeted BX | Systematic BX | Overall BX | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Pearson χ2 | df | sig | Pearson χ2 | df | sig | Pearson χ2 | df | sig | |
| 2 patient groups | 0.458 | 1 | 0.498 | 0.658 | 1 | 0.417 | 0.291 | 1 | 0.590 |
| 3 patient groups | 2.145 | 2 | 0.342 | 2.265 | 2 | 0.322 | 1.373 | 2 | 0.503 |
| 6 patient groups | 4.807 | 5 | 0.440 | 2.872 | 5 | 0.720 | 2.322 | 5 | 0.803 |
Patient and lesion characteristics
| min | max | mean ± SD | median | |
|---|---|---|---|---|
| Age (years) | 35 | 91 | 69.0 ± 7.9 | 70.0 |
| *Total PSA concentration (ng/mL) | 0.45 | 115.4 | 9.7 ± 11.7 | 7.0 |
| Prostate volume (ml) | 15 | 313 | 52.8 ± 32.3 | 45 |
| No. lesions biopsied in a patient | 1 | 3 | 1.4 ± 0.6 | 1.0 |
| Largest diameter of lesion (mm) | 3.0 | 41.0 | 12.8 ± 6.6 | 11.5 |
| No. of cores per lesion targeted BX | 1 | 8 | 4.26 ± 1.2 | 4.0 |
| No. of cores systematic BX | 0 | 14 | 6.9 ± 1.8 | 6.0 |
| No. of MRI-TRUS fusion targeted BX performed by urologist before | 1 | 65 | 22.5 ± 19.7 | 20.0 |
Proportion of positive targeted biopsy (BX) lesions categorised by Prostate Imaging-Reporting and Data System (PIRADS) score
| Negative BX | Positive BX | Total | |
|---|---|---|---|
| PIRADS 3 (%) | 104 (81.9%) | 23 (18.1%) | 127 |
| PIRADS 4 (%) | 108 (52.9%) | 96 (47.1%) | 204 |
| PIRADS 5 (%) | 13 (16.0%) | 68 (84.0%) | 81 |
Results of multiple logistic regression of positive histopathologic result
| Sig | Odds ratio | 95% C.I. for odds ratio | ||
|---|---|---|---|---|
| Lower | Upper | |||
| Max lesion diameter | 0.945 | 0.998 | 0.955 | 1.044 |
| Prostate volume | < 0.001 | 0.978 | 0.968 | 0.988 |
| *Total PSA concentration | 0.050 | 1.050 | 1.000 | 1.103 |
| PIRADS 3 | < 0.001 | |||
| PIRADS 4 | < 0.001 | 3.208 | 1.848 | 5.567 |
| PIRADS 5 | < 0.001 | 16.222 | 6.475 | 40.645 |
| Number of cores per lesion | 0.034 | 1.238 | 1.016 | 1.508 |
| Number of previous patients with targeted BX performed by urologist | 0.113 | 1.013 | 0.997 | 1.028 |