Have a personal or library account? Click to login
Ocular adnexal lymphoma – a retrospective study and review of the literature Cover

Ocular adnexal lymphoma – a retrospective study and review of the literature

Open Access
|Sep 2024

Figures & Tables

FIGURE 1.

Patient with conjunctival lymphoma presents with a characteristic salmon-pink nodular patch in the conjunctiva.
Patient with conjunctival lymphoma presents with a characteristic salmon-pink nodular patch in the conjunctiva.

FIGURE 2.

Patient with orbital lymphoma presents with a mass lesion within the right eye.
Patient with orbital lymphoma presents with a mass lesion within the right eye.

FIGURE 3.

Overall survival.
Overall survival.

FIGURE 4.

Lymphoma specific survival.
Lymphoma specific survival.

Treatment outcome in 58 patients with post-treatment evaluation, post-treatment evaluation being done three to six months after the end of treatment

Treatment outcomeNumber of patients
Complete remission46 (79.3%)
Partial remission10 (17.2%)
Stable disease1 (1.7%)
Progressive disease1 (1.7%)*

Patients’ characteristics

MalesFemalesAll
Number of patients30 (40.5%)44 (59.5%)74
Median age, years72 (range 41 – 89)67.5 (range 34 – 89)68
Lymphoma type
  - Marginal zone lymphoma (MALT)21/30 (70.0%)32/44 (72.7%)53/74 (71.6%)
  - Mantle cell lymphoma (MCL)6/30 (20.0%)3/44 (6.8%)9/74 (12.2%)
  - Follicular lymphoma (FL)2/30 (6.7%)4/44 (9.0%)6/74 (8.1%)
  - Diffuse large B-cell lymphoma (DLBCL)1/30 (3.3%)3/44 (6.8%)4/74 (5.4%)
  - Chronic lymphocytic leukemia (CLL)0/30 (0%)1/44 (2.3%)1/74 (1.4%)
  - Peripheral T-cell lymphoma, not otherwise specified0/30 (0%)1/44 (1.4%)1/74 (1.4%)
Conjunctival lymphoma7/30 (23.3%)11/44 (25.0%)18/74 (24.3%)
Orbital lymphoma23/30 (76.7%)33/44 (75.0%)56/74 (75.7%)

Specifications of orbital and conjunctival lymphomas

Orbital lymphomasConjunctival lymphomasAll
Unilateral lymphoma46/56 (82.1%)17/18 (94.4%)63/74 (85.1%)
Bilateral lymphoma10/56 (17.9%)1/18 (5.6%)11/74 (14.9%)
Lymphoma type
  - Marginal zone lymphoma (MALT)36/56 (64.3%)17/18 (94.4%)53/74 (71.6%)
  - Mantle cell lymphoma (MCL)9/56 (16.1%)0/18 (0%)9/74 (12.2%)
  - Follicular lymphoma (FL)5/56 (8.9%)1/18 (5.6%)6/74 (8.1%)
  - Diffuse large B-cell lymphoma (DLBCL)4/56 (7.1%)0/18 (0%)4/74 (5.4%)
  - Chronic lymphocytic leukemia (CLL)1/56 (1.8%)0/18 (0%)1/74 (1.4%)
  - Peripheral T-cell lymphoma, not otherwise specified1/56 (1.8%)0/18 (0%)1/74 (1.4%)
DOI: https://doi.org/10.2478/raon-2024-0048 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 416 - 424
Submitted on: Apr 30, 2024
Accepted on: Aug 12, 2024
Published on: Sep 15, 2024
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2024 Lucka Boltezar, Danijela Strbac, Joze Pizem, Gregor Hawlina, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution 4.0 License.