FIGURE 1.
FIGURE 2.
FIGURE 3.
Results of the immunochemical reactions in both cases, on cytological and histological samples
| Case | β-Catenin | Cyclin D1 | Synapto physin | Chromo granin | CD56 | PR | CD10 | CKAE1/AE3 | SOX11 |
|---|---|---|---|---|---|---|---|---|---|
| 1 cyto | + | + | −+ | − | + | / | + | − | + |
| 1 histo | + | / | / | / | / | / | / | / | + |
| 2 cyto | + | + | +− | − | −+ | − | + | −+ | + |
| 2 histo | + | + | Focally + | / | / | / | / | / | + |
Pancreatic neoplasms diagnosed by FNAB in the pediatric population: cases in the literature
| Study | No of cases/No with tumour | Sex/age (y) | EUS-FNAB non tumour diagnosis | EUS-FNAB tumour diagnosis | EUS-FNAB complications | Tumour histology | Follow-up |
|---|---|---|---|---|---|---|---|
| Nabi Z et al.8 | 34/23 | NA/Median age 15 (8–18) | Inflammatory mass, Pseudocyst, Lymphoepithelial cyst, Epithelial cyst | SPN (21), Pancreatoblastoma (1), Round cell tumor (1) | Throat pain (7), abdominal pain (2), self-limiting bleeding (2), fever (1) | 88% confirmed EUS-FNA diagnosis | NA |
| Al Rashdan A et al.9 | 9/3 | NA/Median age 16 (4–18) | Cysts, Inflammation | SPN (2), Carcinoid tumour (1) | None | SPN | Uneventful (SPN), Died of metastatic disease (Carcinoid tumour) |
| Gordon K et al.10 | 6/3 | NA/Average weight 70 kg | Pseudocyst (4), multiple unilocular cysts (1) | SPN (2), Insulinoma | Mild pancreatitis (1) | NA | Multiple endocrine neoplasia 1 (Insulinoma) |
| Jia Y et al.11 | 1/0 | F/13 | Simple pancreatic cyst | None | None | None | None |
| Mahida JB et al.12 | 1/1 | F/13 | None | SPN (1) | None | SPN | No recurrence |
| Attila T et al.13 | 6/2(3)* | 4M,2F/10-16 | Focal pancreatitis, Chronic pancreatitis | B-cell lymphoma, Islet cell tumour, Suspicious of malignancy | None | B-cell lymphoma, Islet cell tumour, Sclerosing pancreatitis | Multiple endocrine neoplasia 1 (1), NA |
| Bardales RH et al.14 | 2/2 | F/13, 18 | None | SPN (2) | NA | SPN | None |
| Nadler EP et al.15 | 1/1 | F/13 | None | SPN (1) | None | SPN | No recurrence. |