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Modern approach to the management of genitourinary syndrome in women with gynecological malignancies Cover

Modern approach to the management of genitourinary syndrome in women with gynecological malignancies

Open Access
|Jul 2023

Abstract

Background

The term genitourinary syndrome of menopause was first used in 2014 by the North American Menopause Society and the International Society for the Study of Women's Sexual Health to describe conditions previously known as atrophic vaginitis, urogenital atrophy, or vulvovaginal atrophy. It is a complex, chronic, progressive condition characterized by a wide range of signs and symptoms affecting sexual function and the tissues of the urinary and genital tracts. The main cause of genitourinary syndrome of menopause is estrogen deficiency caused by ovarian removal or dysfunction. The most bothersome symptoms are vaginal dryness, decreased vaginal lubrication, and pain during penetration and intercourse. They all have a negative impact on the quality of life.

Conclusions

The main goal of treatment is to relieve the symptoms. Treatment modalities are pharmacological or non-pharmacological. The first-line treatment for mild to moderate symptoms is the use of personal lubricants and moisturizers, but the gold standard is estrogen replacement therapy. Hormone therapy may not be an option for women with hormone-dependent cancer.

DOI: https://doi.org/10.2478/raon-2023-0038 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 292 - 298
Submitted on: May 15, 2023
Accepted on: Jun 25, 2023
Published on: Jul 26, 2023
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2023 Nina Kovacevic, Ines Cilensek, Sebastjan Merlo, Barbara Segedin, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution 4.0 License.