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Longitudinal monitoring of Apparent Diffusion Coefficient (ADC) in patients with prostate cancer undergoing MR-guided radiotherapy on an MR-Linac at 1.5 T: a prospective feasibility study Cover

Longitudinal monitoring of Apparent Diffusion Coefficient (ADC) in patients with prostate cancer undergoing MR-guided radiotherapy on an MR-Linac at 1.5 T: a prospective feasibility study

Radiology and Oncology
Volume 57 (2023): Issue 2 (June 2023)
By:
Open Access
|Jun 2023

Figures & Tables

FIGURE 1.

Flow diagram illustrating the inclusion/exclusion process.
Flow diagram illustrating the inclusion/exclusion process.

FIGURE 2.

T2-weighted MR images (scan time: 2 minutes) and apparent diffusion coefficient (ADC) maps of a 66-year-old male patient with prostate cancer in the antero-apical region of the transition zone (red arrows) at baseline (left column) and during radiotherapy (right column) as recorded on MR-Linac (MRL) and on standard MRI at 3T (MRI3T). The figure shows similar dynamics of lesion ADC elevation during radiotherapy.
T2-weighted MR images (scan time: 2 minutes) and apparent diffusion coefficient (ADC) maps of a 66-year-old male patient with prostate cancer in the antero-apical region of the transition zone (red arrows) at baseline (left column) and during radiotherapy (right column) as recorded on MR-Linac (MRL) and on standard MRI at 3T (MRI3T). The figure shows similar dynamics of lesion ADC elevation during radiotherapy.

FIGURE 3.

Scatter plots with a fitted line for ADC values as recorded on MR-Linac and MRI3T for reader 1. (A) at baseline, (B) during radiotherapy (week 2). These plots illustrate the strong positive correlation between MRL-ADC and MRI3T-ADC at both time points.
Scatter plots with a fitted line for ADC values as recorded on MR-Linac and MRI3T for reader 1. (A) at baseline, (B) during radiotherapy (week 2). These plots illustrate the strong positive correlation between MRL-ADC and MRI3T-ADC at both time points.
DOI: https://doi.org/10.2478/raon-2023-0020 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
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Language: English
Page range: 184 - 190
Submitted on: Jan 20, 2023
Accepted on: Mar 30, 2023
Published on: Jun 21, 2023
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
Keywords:
prostate carcinoma,
MRI,
adaptive radiotherapy,
image guidance,
MR-Linac,
ADC
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Haematology, oncology,
Radiology

© 2023 Haidara Almansour, Fritz Schick, Marcel Nachbar, Saif Afat, Victor Fritz, Daniela Thorwarth, Daniel Zips, Felix Bertram, Arndt-Christian Müller, Konstantin Nikolaou, Ahmed E Othman, Daniel Wegener, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution 4.0 License.

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