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Radiomic features as biomarkers of soft tissue paediatric sarcomas: preliminary results of a PET/MR study Cover

Radiomic features as biomarkers of soft tissue paediatric sarcomas: preliminary results of a PET/MR study

Radiology and Oncology
Volume 56 (2022): Issue 2 (June 2022)
By:
Open Access
|Mar 2022

Figures & Tables

Figure 1

Graphic representation of the development of the proposed radiomic analysis demonstrating the segmentation and extraction of radiomic features from the primary lesion of children affected by soft tissue sarcomas examined for staging by PET/MR and the factor analysis that led to the selection of five highly correlating variables.
Graphic representation of the development of the proposed radiomic analysis demonstrating the segmentation and extraction of radiomic features from the primary lesion of children affected by soft tissue sarcomas examined for staging by PET/MR and the factor analysis that led to the selection of five highly correlating variables.

Comparison of demographics, metabolic, and first-line laboratory variables according to tumor histotype and grade

Histotype*Grade#
RhabdomyosarcomaNon-rhabdomyosarcomapaLow-gradeHigh gradepa
Age (years)7.2 ± 4.89 ± 4.20.4646.1 ± 3.49.5 ± 5.20.115
Gender (female/male)7/54/21.0007/24/50.335
SUVmax5.1 ± 35.6 ± 30.7655.3 ± 45.3 ± 20.998
SUVmean1.8 ± 11.5 ± 10.5051.1 ± 0.31 ± 0.20.960
Hemoglobin (g/L)11.4 ± 1.311.7 ± 1.40.66011.7 ± 1.611.4 ± 10.657
Red (×10blood 12·L−1) cells count4.2 ± 14.7 ± 0.50.2154.3 ± 14.5 ± 10.594
White (×109·Lblood −1) cells count5.8 ± 35.8 ± 50.9965.7 ± 46 ± 3.90.889
Platelets (×109·L−1)349 ± 171386 ± 770.636375 ± 187351 ± 1000.748
Lactate (U/L) dehydrogenase335 ± 86369 ± 1720.608358 ± 131331 ± 940.652
D-(ng/dimer mL)214 ± 1522125 ± 35300.071370 ± 2992331 ± 2970.315
DOI: https://doi.org/10.2478/raon-2022-0013 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
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Language: English
Page range: 138 - 141
Submitted on: Nov 19, 2021
Accepted on: Mar 4, 2022
Published on: Mar 28, 2022
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
Keywords:
pediatric soft tissue sarcomas,
PET/MR,
radiomics,
oncology
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Haematology, oncology,
Radiology

© 2022 Chiara Giraudo, Giulia Fichera, Roberto Stramare, Gianni Bisogno, Raffaella Motta, Laura Evangelista, Diego Cecchin, Pietro Zucchetta, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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