Figure 1
Figure 2
Figure 3
Figure 4
Mean T2 and T2 variability values of parotid glands in patients following radiotherapy for head and neck tumours before and after hyperbaric oxygenation therapy (HBOT) and in healthy controls
| Ipsilateral side (N = 18) | Contralateral side (N = 18) | Controls (N = 18) | |||
|---|---|---|---|---|---|
| before HBOT | after HBOT | before HBOT | after HBOT | ||
| MEAN T2 (ms) | 121 ± 20† | 113 ± 16†* | 107 ± 21** | 103 ± 14 | 96 ± 12 |
| T2 VARIABILITY (ms) | 30 ± 8 | 25 ± 8* | 21 ± 8 | 19 ± 6 | 16 ± 4 |
Correlations between mean T2 or T2variability and pH of unstimulated saliva before and after hyperbaric oxygenation therapy (HBOT) (R-correlation coefficients and p-values)
| Ipsilateral side (N = 18) | Contralateral side (N = 18) | |||||||
|---|---|---|---|---|---|---|---|---|
| before HBOT | after HBOT | before HBOT | after HBOT | |||||
| R | p | R | p | R | p | R | p | |
| Mean T2 (ms) | -0.647 | 0.0037 | -0.571 | 0.0133 | -0.557 | 0.0164 | -0.675 | 0.0021 |
| T2 variability (ms) | -0.595 | 0.0092 | -0.506 | 0.0323 | -0.130 | 0.607 | -0.588 | 0.0133 |
Salivary flow, pH, and buffer capacity in patients following radiotherapy for head and neck tumours before and after hyperbaric oxygenation therapy (HBOT) and in healthy controls
| before HBOT (N = 18) | after HBOT (N = 18) | Controls (N = 18) | |
|---|---|---|---|
| Unstimulated (median and salivary IQR) flow (mL/min) | 0.22 (0.04-0.54) † | 0.32 (0.08-0.70)*† | 0.61 (0.49-0.99) |
| pH (mean of unstimulated ± SD) saliva | 6.61± 0.69† | 6.72 ± 0.71† | 7.56 ± 0.53 |
| Stimulated (mean ± SD) salivary flow (mL/min) | 0.82 ± 0.60† | 0.90 ± 0.64† | 2.04 ± 0.91 |
| pH (mean of stimulated ± SD) saliva | 7.38 ± 0.74† | 7.48 ± 0.51† | 8.00 ± 0.28 |
| Buffering (median capacity and IQR) of stimulated saliva | 2.00 (1.75-3.00) | 3.00 (2.00-3.00)* | 3.00 (2.00-3.00) |