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Diagnostic performance of apparent diffusion coefficient values for the differentiation of intrahepatic cholangiocarcinoma from gastrointestinal adenocarcinoma liver metastases Cover

Diagnostic performance of apparent diffusion coefficient values for the differentiation of intrahepatic cholangiocarcinoma from gastrointestinal adenocarcinoma liver metastases

Radiology and Oncology
Volume 56 (2022): Issue 1 (March 2022)
By: Temel Fatih Yilmaz,  Mehmet Ali Gultekin,  Hacı Mehmet Turk,  Mehmet Besiroglu,  Dilek Hacer Cesme,  Melih Simsek,  Alpay Alkan and  Huseyin Toprak  
Open Access
|Dec 2021

Figures & Tables

Figure 1

Flow-chart of the study showing the exclusion criteria of the patients.
Flow-chart of the study showing the exclusion criteria of the patients.

Figure 2

59-year-old male with liver metastases due to colorectal adenocarcinoma. Contrast-enhanced axial T1-weighted (T1W) (A), diffusion weighted image (DWI) obtained at b value of 800 s/mm2 (B) and apparent diffusion coefficient (ADC) maps (C) with free hand ROI placement technique.
59-year-old male with liver metastases due to colorectal adenocarcinoma. Contrast-enhanced axial T1-weighted (T1W) (A), diffusion weighted image (DWI) obtained at b value of 800 s/mm2 (B) and apparent diffusion coefficient (ADC) maps (C) with free hand ROI placement technique.

Figure 3

58-year-old female with an expansile liver mass with central hypovascular fibrous stroma and peripheral contrast enhancement on contrastenhanced axial T1-weighted (T1W) (A) images. diffusion weighted image (DWI) obtained at b value of 800 s/mm2 (B) and apparent diffusion coefficient (ADC) maps (C) with region of interests (ROI) placement with three different contrast enhancing area for calculating ADCmean values.
58-year-old female with an expansile liver mass with central hypovascular fibrous stroma and peripheral contrast enhancement on contrastenhanced axial T1-weighted (T1W) (A) images. diffusion weighted image (DWI) obtained at b value of 800 s/mm2 (B) and apparent diffusion coefficient (ADC) maps (C) with region of interests (ROI) placement with three different contrast enhancing area for calculating ADCmean values.

Figure 4

Mean apparent diffusion coefficient (ADCmean) values of liver metastases of gastrointestinal system adenocarcinomas and intrahepatic cholangiocarcinoma (IHCC).
Mean apparent diffusion coefficient (ADCmean) values of liver metastases of gastrointestinal system adenocarcinomas and intrahepatic cholangiocarcinoma (IHCC).

Figure 5

Receiver operating characteristic curve of the apparent diffusion coefficient (ADC) mean values.
Receiver operating characteristic curve of the apparent diffusion coefficient (ADC) mean values.

Apparent diffusion coefficient (ADC) values of intrahepatic cholangiocarcinoma (IHCC) and gastrointestinal system (GIS) liver metastases

Patient GroupsADC x 10-6mm/sn2 (median, IQR)
IHCC(1293.0), (1422.0–951.75)
GIS metastases(861.0), (1053.0–695.0)

Univariate analysis of patient characteristics for gastrointestinal system (GIS) liver metastases and intrahepatic cholangiocarcinoma (IHCC)

Patient characteristicsNumber of patients (n = 63)IHCC (n = 10)Liver metastases (n = 53)P value
Age (years)61.4 ± 9.9362.50 ± 13.4961.15 ± 9.180.679
Gender < 0.001
Male35233
Female28820
Diameter Location (mm)47 ± 31.2782.70 ± 28.5840.26 ± 27< < 0.001 0.001
Right lobe24238
Left lobe43815
DOI: https://doi.org/10.2478/raon-2021-0052 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
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Language: English
Page range: 54 - 59
Submitted on: Jul 29, 2021
Accepted on: Nov 4, 2021
Published on: Dec 22, 2021
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
cholangiocarcinoma,
gatrointestinal system,
liver metastases,
apparent diffusion coefficient,
diffusion weighted image,
MRI
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Haematology, oncology,
Radiology

© 2021 Temel Fatih Yilmaz, Mehmet Ali Gultekin, Hacı Mehmet Turk, Mehmet Besiroglu, Dilek Hacer Cesme, Melih Simsek, Alpay Alkan, Huseyin Toprak, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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