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Microwave ablation compared with radiofrequency ablation for the treatment of liver cancer: a systematic review and meta-analysis Cover

Microwave ablation compared with radiofrequency ablation for the treatment of liver cancer: a systematic review and meta-analysis

Open Access
|Jun 2021

Figures & Tables

Figure 1

Prisma flow diagram.MWA = microwave ablation, RFA = radiofrequency ablation, TACE = transarterial chemoembolization
Prisma flow diagram.MWA = microwave ablation, RFA = radiofrequency ablation, TACE = transarterial chemoembolization

Figure 2

Forest plot of random-effects meta-analysis results for complete ablation rates in the MWA and RFA group.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation
Forest plot of random-effects meta-analysis results for complete ablation rates in the MWA and RFA group.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation

Figure 3

Forest plot of random-effects meta-analysis results for local tumor progression in the RFA and MWA group.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation
Forest plot of random-effects meta-analysis results for local tumor progression in the RFA and MWA group.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation

Figure 4

Forest plot of random-effects meta-analysis results for local tumor progression in the RFA and MWA group based on the study type.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation
Forest plot of random-effects meta-analysis results for local tumor progression in the RFA and MWA group based on the study type.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation

Figure 5

Forest plot of random-effects meta-analysis results for intrahepatic distant recurrence rates in the RFA and MWA group.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation
Forest plot of random-effects meta-analysis results for intrahepatic distant recurrence rates in the RFA and MWA group.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation

Figure 6

Forest plot of random-effects meta-analysis results for complication rates following RFA and MWA.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation
Forest plot of random-effects meta-analysis results for complication rates following RFA and MWA.CI = confidence interval, MWA = microwave ablation, OR = odds ratio, RFA = radiofrequency ablation

Study and baseline characteristics of studies included in the meta-analysis

StudyCountyStudy DesignTumorRFA, nMWA, nAge, RFAAge, MWAChild-Pugh A/B/C, RFAChild-Pugh A/B/C, MWATumor size (cm), RFATumor size (cm), MWATumor lesions, RFATumor lesions, MWA
Kamal 2019 (13)EgyptRCTHCC2828555522.6.200022.6.20003.28 ± 0.913.25 ± 0.923434
Vietti Violi 2018 (14)France/SwitzerlandRCTHCC737165 (median)68 (median)53/20/057/14/01.8 ± 0.711.8 ± 0.6510498
Abdelaziz 2014 (15)EgyptRCTHCC456656.8 ± 7.353.6 ± 524/21/025/41/02.95 ± 1.032.9 ± 0.975276
Di Vece 2013 (16)ItalyRCTHCC/Metastases202059 (median)63 (median)N/RN/R3.2 (median)3.6 (median)2020
Qian 2012 (17)ChinaProspectiveHCC202256 ± 1152 ± 1220/0/022/0/02 ± 0.52.1 ± 0.42022
Sparchez 2019 (18)RomaniaRetrospectiveMetastases441760.18 ± 9.9662.12 ± 10.73--2.majfeb.556220
Takahashi 2018 (19)USARetrospectiveCRLM5451N/RN/R--2.4 (median)2.1 (median)155121
Shady 2018 (20)USARetrospectiveCRLM6248N/RN/R--1.8 (median)1.7 (median)8560
Xu 2017 (21)ChinaRetrospectiveHCC15930154 ± 1154.2 ± 11140/19/0278/23/01.7 ± 0.31.7 ± 0.3159301
van Tilborg 2016 (38)NetherlandsRetrospectiveCRLMTotal number of participants: 122N/RN/R--2.apr2.maj15148
Potretzke 2016 (23)USARetrospectiveHCC55996261N/RN/R2.apr2.feb69136
Zhang X. 2014 (24)ChinaRetrospectiveHCC/Metastases9223051.5 ± 14.355.7 ± 13.2N/RN/R5.4 ± 1.95.7 ± 2.1173349
Zhang L. 2013 (25)ChinaRetrospectiveHCC787754 ± 10.554 ± 9.578/0/077/0/02.3 ± 0.42.2 ± 0.497105
Liu 2013 (26)ChinaRetrospectiveMetastases543553.1 ± 12.753.4 ± 15.3--2.5 ± 1.02.3 ± 1.07062
Ding 2013 (27)ChinaRetrospectiveHCC8511358.64 ± 8.5259.06 ± 11.6849/36/075/30/02.38 ± 0.812.55 ± 0.8998131
DOI: https://doi.org/10.2478/raon-2021-0030 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 247 - 258
Submitted on: Apr 5, 2021
Accepted on: May 10, 2021
Published on: Jun 25, 2021
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2021 Antonios E. Spiliotis, Gereon Gäbelein, Sebastian Holländer, Philipp-Robert Scherber, Matthias Glanemann, Bijendra Patel, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.