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Five-year follow-up and clinical outcome in euthyroid patients with thyroid nodules Cover

Five-year follow-up and clinical outcome in euthyroid patients with thyroid nodules

Open Access
|May 2021

Figures & Tables

Figure 1

Flowchart explaining the recruitment process and the number of included patients and thyroid nodules.
Flowchart explaining the recruitment process and the number of included patients and thyroid nodules.

Figure 2

Nodule largest diameter distribution at baseline (N = 203).
Nodule largest diameter distribution at baseline (N = 203).

Figure 3

Growth status of the nodules after 5 years (N = 203). A significant change in the size of a thyroid nodule was defined as the increase or decrease that involved at least 2 nodule dimensions, each amounting to at least 2 mm and representing at least 20% of the baseline diameter.
Growth status of the nodules after 5 years (N = 203). A significant change in the size of a thyroid nodule was defined as the increase or decrease that involved at least 2 nodule dimensions, each amounting to at least 2 mm and representing at least 20% of the baseline diameter.

Figure 4

Correlations of baseline parameters with change in the largest nodule diameter and change in the nodule volume in nodules that significantly increased in size at the five-year follow-up (N = 58).
Correlations of baseline parameters with change in the largest nodule diameter and change in the nodule volume in nodules that significantly increased in size at the five-year follow-up (N = 58).

Basic characteristics of patients included in the study (N = 118)

ParameterAll patients (N = 118)Nodule GrowthNew nodules detected

Without (N = 72)With (N = 46)pWithout (N = 102)With (N = 16)p
Age (years)51.6 ± 13.451.8 ± 13.651.2 ± 13.20.8151.2 ± 13.653.9 ± 11.90.46
TSH (mIU/L)1.64 ± 0.851.73 ± 0.831.49 ± 0.850.071.63 ± 0.831.72 ± 1.000.80
Tg (μg/L)42.4 ± 184.951.3 ± 237.228.8 ± 33.40.0843.7 ±196.633.2 ± 70.50.68
Maximum diameter of the largest nodule (mm)12.2 ± 8.211.7 ± 8.412.9 ± 7.70.1112.2 ± 8.312.2 ± 7.60.86
Volume of the largest nodule (mL)1.4 ± 2.41.4 ± 2.61.4 ± 2.10.171.4 ± 2.51.2 ± 1.40.70
Multinodularity (%)55 (46.6%)27 (37.5%)28 (60.9%)0.0248 (47.1%)7 (43.8%)1.0
DOI: https://doi.org/10.2478/raon-2021-0025 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 317 - 322
Submitted on: Dec 5, 2020
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Accepted on: Apr 15, 2021
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Published on: May 31, 2021
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:

© 2021 Katica Bajuk Studen, Simona Gaberscek, Edvard Pirnat, Katja Zaletel, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.