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Long term results of follow-up after HPV self-sampling with devices Qvintip and HerSwab in women non-attending cervical screening programme Cover

Long term results of follow-up after HPV self-sampling with devices Qvintip and HerSwab in women non-attending cervical screening programme

Radiology and Oncology
Volume 55 (2021): Issue 2 (June 2021)
By: Teodora Bokan,  Urska Ivanus,  Tine Jerman,  Iztok Takac and  Darja Arko  
Open Access
|Jan 2021

Figures & Tables

Figure 1

Flow chart of women enrolled in the study with results of human papillomaviruses (HPV) self-sampling and histological cervical intraepithelial neoplasia grade 2 or more (CIN2+) results after one and four-year follow-up.
Flow chart of women enrolled in the study with results of human papillomaviruses (HPV) self-sampling and histological cervical intraepithelial neoplasia grade 2 or more (CIN2+) results after one and four-year follow-up.

Figure 2

Sensitivity and specificity for cervical intraepithelial neoplasia grade 2 or more (CIN2+) by test (cytology, human papillomaviruses [HPV]), testing modality (self, clinician) and self-sampling device (Qvintip, HerSwab) after four years of follow-up following enrolment.ASC-US+ = atypical squamous cells of undetermined significance or more
Sensitivity and specificity for cervical intraepithelial neoplasia grade 2 or more (CIN2+) by test (cytology, human papillomaviruses [HPV]), testing modality (self, clinician) and self-sampling device (Qvintip, HerSwab) after four years of follow-up following enrolment.ASC-US+ = atypical squamous cells of undetermined significance or more

Figure 3

Positive predictive value and negative predictive value for cervical intraepithelial neoplasia grade 2 or more (CIN2+) by test (cytology, human papillomaviruses [HPV]), testing modality (self, clinician) and self-sampling device (Qvintip, HerSwab).ASC-US+ = atypical squamous cells of undetermined significance or more
Positive predictive value and negative predictive value for cervical intraepithelial neoplasia grade 2 or more (CIN2+) by test (cytology, human papillomaviruses [HPV]), testing modality (self, clinician) and self-sampling device (Qvintip, HerSwab).ASC-US+ = atypical squamous cells of undetermined significance or more

Figure 4A

Cumulative incidence of cervical intraepithelial neoplasia grade 2 or more (CIN2+) according to human papillomaviruses (HPV) test result in Qvintip group
Cumulative incidence of cervical intraepithelial neoplasia grade 2 or more (CIN2+) according to human papillomaviruses (HPV) test result in Qvintip group

Figure 4B

Cumulative incidence of cervical intraepithelial neoplasia grade 2 or more (CIN2+) according to human papillomaviruses (HPV) test result in HerSwab group.
Cumulative incidence of cervical intraepithelial neoplasia grade 2 or more (CIN2+) according to human papillomaviruses (HPV) test result in HerSwab group.

Concordance of human papillomavirus (HPV) test results (among devices) and cytology (among laboratories)

HPV testCytology
OPA (%)kappa (95% CI)OPAa (%)kappa (95% CI)
Qvintip group81.80.534 (0.349–0.718)74.80.471 (0.3029–0.641)
HerSwab group77.10.456 (0.2569–0.655)74.50.406 (0.2059–0.607)
Total79.60.495 (0.3599–0.632)74.60.444 (0.3159–0.574)
DOI: https://doi.org/10.2478/raon-2021-0001 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
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Language: English
Page range: 187 - 195
Submitted on: Oct 1, 2020
|
Accepted on: Dec 9, 2020
|
Published on: Jan 6, 2021
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
HPV self-sampling,
cytology,
high-grade intraepithelial lesion
Related subjects:
Medicine,
Clinical medicine,
Internal medicine,
Haematology, oncology,
Radiology

© 2021 Teodora Bokan, Urska Ivanus, Tine Jerman, Iztok Takac, Darja Arko, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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