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Correlations between DTI-derived metrics and MRS metabolites in tumour regions of glioblastoma: a pilot study Cover

Correlations between DTI-derived metrics and MRS metabolites in tumour regions of glioblastoma: a pilot study

Open Access
|Sep 2020

Figures & Tables

Figure 1

(A-F) magnetic resonance spectroscopy (MRS) measurements at the enhancing rim and peritumoral edema. (G-I) example of a FA map used to locate the ROI at the selected regions: enhancing rim, peritumoral oedema, and normal-appearing white matter (NAWM).

Figure 2

Scatter plots showing the correlation between magnetic resonance spectroscopy (MRS) metabolites and diffusion tensor imaging (DTI) metric at the normal-appearing white matter (NAWM).

Table 1

Correlations between diffusion tensor imaging (DTI) metrics and magnetic resonance spectroscopy (MRS) metabolites for the normal-appearing white matter (NAWM) region

graphic/j_raon-2020-0055_ingr_001.png

[i] Cho/Naa = choline-to-N-acetyl aspartate; LL/Cr = lipids and lactate to creatine; mI/Cr = and myo-inositol/creatine [mI/Cr]

Figure 3

Scatter plots showing the correlation between magnetic resonance spectroscopy (MRS) metabolites and diffusion tensor imaging (DTI) metric at the enhancing rim.

Table 2

Correlations between diffusion tensor imaging (DTI) metrics and magnetic resonance spectroscopy (MRS) metabolites for the tumour region

graphic/j_raon-2020-0055_ingr_002.png

[i] Cho/Naa = choline-to-N-acetyl aspartate; LL/Cr = lipids and lactate to creatine; mI/Cr = and myo-inositol/creatine

Figure 4

Scatter plots showing the correlation between magnetic resonance spectroscopy (MRS) metabolites and diffusion tensor imaging (DTI) metric at the peritumoral edema.

Figure 5

Diagram representation of the significant correlations between diffusion tensor imaging (DTI)- magnetic resonance spectroscopy (MRS) biomarkers at the selected regions: normal-appearing white matter (NAWM), enhancing rim and peritumoral edema. Notice that NAWM and the enhancing rim share four pairs of biomarkers correlations; while in peritumoral oedema ten pairs of correlations were exclusive of that region.

Table 3

Correlations between diffusion tensor imaging (DTI) metrics and magnetic resonance spectroscopy (MRS) metabolites for the oedema region

graphic/j_raon-2020-0055_ingr_003.png

[i] Cho/Naa = choline-to-N-acetyl aspartate; LL/Cr = lipids and lactate to creatine; mI/Cr = and myo-inositol/creatine

DOI: https://doi.org/10.2478/raon-2020-0055 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 394 - 408
Submitted on: Jul 9, 2020
Accepted on: Jul 31, 2020
Published on: Sep 29, 2020
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2020 Eduardo Flores-Alvarez, Edgar Anselmo Rios Piedra, Griselda-Adriana Cruz-Priego, Coral Durand-Muñoz, Sergio Moreno-Jimenez, Ernesto Roldan-Valadez, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.