A comparison between the prognostic factors of the three main recognized staging systems (the Liver Cancer Study Group of Japan [LCSGJ]9, the National Cancer Center of Japan [NCCJ]53, and the American Joint Committee on Cancer [AJCC, 8th edition38], Wang et al_49 and Hyder et al_43 nomograms
| Tumor diameter | Number of lesion | Extent of disease | Nodal Invasion | Vascular invasion | Metastatic disease | Other prognostic factors | |
|---|---|---|---|---|---|---|---|
| LCSGJ9 | Cut-off: 2 cm | Yes | Invasion serosa of the | Yes | Yes | Yes | |
| NCCJ53 | Yes | Yes | Yes | Symptoms | |||
| AJCC38 | Cut-off: 5 cm | Yes | Yes | Yes | Yes | ||
| Wang et al.49 | Yes | Yes | Yes | Yes | Yes | CACEA 19.9 | |
| Hyder et al.43 | Yes | Yes | Yes | Yes | Cirrhosis Age |