Influence of tumor characteristics on primary efficacy
| Predictor | Estimate | Std.err | Wald | p-value | |
|---|---|---|---|---|---|
| Long axis, mm | ≤ 30 | Reference | 0.3657 | 5.68 | 0.0171 |
| Guidance | Freehand | Reference | 0.3256 | 6.13 | 0.0133 |
| HCC | Reference | ||||
| Tumor entity | CRC | 0.2922 | 0.4483 | 0.42 | 0.5145 |
| Other | 0.0832 | 0.5228 | 0.03 | 0.8736 | |
| I | Reference | ||||
| II | − 0.3956 | 1.0798 | 0.13 | 0.7141 | |
| III | − 0.0449 | 1.1025 | 0.00 | 0.9675 | |
| IVa | 0.2688 | 1.1180 | 0.06 | 0.8100 | |
| Liver segment | IVb | − 0.2539 | 1.1597 | 0.05 | 0.8267 |
| V | 0.5961 | 1.1285 | 0.28 | 0.5974 | |
| VI | 0.9036 | 1.1736 | 0.59 | 0.4413 | |
| VII | 0.0656 | 1.1090 | 0.00 | 0.9528 | |
| VIII | − 0.1069 | 1.0929 | 0.01 | 0.9221 |
Monte Carlo simulation of primary technique efficacy rate depending on tumor size and antenna guidance
| Long axis, mm | Guidance | CI-2.5% | Median | CI-97.5% |
|---|---|---|---|---|
| ≤ 30 | Freehand | 0.60 | 0.75 | 0.86 |
| > 30 | Freehand | 0.34 | 0.55 | 0.76 |
| ≤ 30 | Robotic | 0.78 | 0.87 | 0.92 |
| > 30 | Robotic | 0.55 | 0.74 | 0.87 |
Tumors treated using freehand and robotic guidance
| Ablation technique | Long axis, mm | Liver segment, n (%) | Device, n (%) | Primary efficacy, n (%) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Min | Mean (SD) | Max | I | II | III | IVa | IVb | V | VI | VII | VIII | Acculis | Emprint | Complete | Incomplete | |
| Freehand (n = 119) | 4 | 19.79 | 85 | 1 | 10 | 16 | 16 | 9 | 13 | 17 | 15 | 22 | 65 | 54 | 9 | 28 |
| Robotic guidance (n = 249) | 3 | 18.78 | 64 | 6 | 24 | 20 | 26 | 16 | 38 | 36 | 36 | 47 | 143 | 106 | 219 | 30 |
Patient characteristics
| Age, years | Sex, n, (%) | Treated tumors per patient, n | Tumor entity, n (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Min. | Mean (SD) | Median (IQR) | Max. | Male | Female | Median (IQR) | Max. | HCC | CRC | CCC | Other | |
| Patients (n = 192) | 15 | 65.03 | 64.00 | 83 | 156 | 36 | 1.00 | 9 | 139 (72) | 29 | 7 | 17 |