Effect of radiotherapy on coronary arteries and heart in breast-conserving surgery: a dosimetric analysis

Figures & Tables

		Right-sided breast cancer n (%)	Left-sided breast cancer n (%)
Breast conservation surgery		20 (100%)	20 (100%)
Age		57.33 ± 10.21(40–80)	61.35 ± 9.91(42–76)
T stage	T1	15 (75%)	12 (60%)
T stage	T2	5 (25%)	8 (40%)
N stage	N0	20 (100%)	20 (100%)
M stage	M0	20 (100%)	20 (100%)
Tumor location	inner quadrant	6 (30%)	10 (50%)
Tumor location	outer quadrant	14 (70%)	10 (50%)
Tumor size	≤ 2 cm	15 (75%)	12 (60%)
Tumor size	2–5 cm	5 (25%)	8 (40%)
Chemotherapy	Yes	7 (35%)	11 (55%)
Chemotherapy	No	13 (65%)	9 (45%)
Number of chemotherapy cycles	4	4 (20%)	6 (30%)

	6	3 (15%)	5 (25%)

Dosimetric parameters		Right-sided breast cancer	Left-sided breast cancer	P value
LAD	D_mean	97.57 ± 10.26(73.8–114)	2402.48 ± 838.39(1020–3783)	< 0.0001
	D_max	111.87 ± 16.15(78.8–145)	4752.83 ± 498.46(3700–5703.8)	< 0.0001
	D_min	83.12 ± 9.31(63.7–100.1)	222.59 ± 76.42(95–471)	< 0.0001
LCx	D_mean	84.99 ± 9.09(63.8–100.8)	170.55 ± 45.36(85.8–260.2)	< 0.0001
	D_max	96.27 ± 11.33(75.6–116.3)	203.49 ± 55.9(112–353.9)	< 0.0001
	D_min	74.59 ± 8.57(54.5–92.1)	137.63 ± 38.59(69.7–235.5)	< 0.0001
RV	D_mean	130.18 ± 24.92(110.8–224.2)	563.65 ± 221.78(140.9–875.6)	< 0.0001
	D_max	464.76 ± 517.55(221.2–2619)	4576.55±1077.66(460.1–6149.3)	< 0.0001
	D_min	75.51 ± 7.81(58.8–90.5)	103.41 ± 28.67(49.3–184.9)	< 0.0001
LV	D_mean	81.71 ± 7.9(60.9–96.5)	536.8 ± 193.24(230–1018.1)	< 0.0001
	D_max	149.13 ± 43.75(85.1–264.2)	4822.6 ± 362.4(3964.4–5835.4)	< 0.0001
	D_min	65.75 ± 7.02(47.1–80.2)	105.49 ± 26.64(52.2–184.2)	< 0.0001
Heart	D_mean	120.33 ± 19.05(97.3 – 189.2)	396.56 ± 131.73(158.5–588.7)	< 0.0001
Heart	D_max	634.48 ± 751.55(277–3759.5)	5032.44 ± 331.02(4134.3–5992.9)	< 0.0001