Figure 1

Figure 2

Baseline clinical, radiological and pathological characteristics of the two patients who died in two months time after radical treatment of early-stage non-small cell lung cancer due to acute exacerbation of idiopathic pulmonary fibrosis (IPF)
| Characteristics | Patient No. 1 | Patient No. 2 |
|---|---|---|
| Gender | Male | Male |
| Age, years | 73 | 81 |
| Smoking status | Former-smoker | Former-smoker |
| FEV1/FVC before operation | 72% | 70% |
| FEV1 before operation | 2800 ml (93%) | 3110 ml (121%) |
| FVC before operation | 3900 ml (94%) | 4570 ml (122%) |
| DLCO before operation | 57% | 47% |
| Histological subtype | Squamous cell carcinoma | Squamous cell carcinoma |
| Pathologic TNM stage (8th edition) | IIIA | IA |
| Lobe distribution | Left lower lobe | Left lower lobe |
| Type of operation | Lobectomy | Lobectomy |
| Adjuvant therapy | Chemotherapy and radiotherapy | No |
| Time from the end of radical treatment till death | 54 days after finishing radiotherapy | 14 days after surgical resection |
Baseline clinical, radiological and pathological characteristics of patients with early-stage non-small cell lung cancer and idiopathic interstitial pneumonia
| Characteristics | N = 13 (%) | |
|---|---|---|
| Gender | Male | 11 (84.6) |
| Female | 2 (15.4) | |
| Age, years | 73.3 ± 4 | |
| Current smoker | 3 (23.1) | |
| Smoking status | Former-smoker | 8 (61.5) |
| Never-smoker | 2 (15.4) | |
| FEV1/FVC before operation | 0.71 ± 0.08 | |
| FEV1 before operation | ml % | 2769 ± 690 101.6 ± 20 |
| FVC before operation | ml % | 3910 ± 818 105 ±19 |
| DLCO before operation | % | 74.2 ±21 |
| Squamous cell carcinoma | 7 (53.8) | |
| Histological subtype | Adenocarcinoma | 5 (38.5) |
| Adenosquamous cell carcinoma | 1 (7.7) | |
| pT1a | 3 (23.0) | |
| pT2a | 6 (46.2) | |
| pT2b | 4 (30.8) | |
| Pathologic TNM stage | IA | 2 (15.4) |
| (8th edition) | IB | 2 (15.4) |
| IIA | 3 (23.0) | |
| IIB | 4 (30.8) | |
| IIIA | 2 (15.4) | |
| Left lower lobe | 7 (53.8) | |
| Lobe distribution | Right lower lobe | 4 (30.8) |
| Right middle lobe | 2 (15.4) | |
| Type of operation | Lobectomy Bilobectomy | 11 (84.6) 2 (15.4) |
| Adjuvant chemotherapy | 4 (30.8) | |
| Adjuvant therapy | Adjuvant radiotherapy | 1 (7.7) |