Figure 1
Figure 2
Patient’s characteristics, tumor, treatment and outcome
| Characteristic | Without diabetes mellitus (N = 161) | With diabetes mellitus (N = 39) | p-value | |
|---|---|---|---|---|
| Age (years) - mean | 62.18 (SD ± 11.8) | 65.26 (SD ± 8.9) | 0.13 | |
| Gender | Male | 106 | 25 | 0.84 |
| Female | 55 | 14 | ||
| American Society of | I | 14 | 0 | |
| Anesthesiologists physical status | II | 95 | 10 | 0.0001 |
| classification score | III | 47 | 29 | |
| IV | 5 | 0 | ||
| Body mass index (kg/m2) - mean | 26.83 (SD ± 4.20) | 29.06 (SD ± 4.1) | 0.003 | |
| Insulin only | - | 5 | ||
| Treatment of diabetes | Metformin only | - | 19 | - |
| 2 or 3 oral antidiabetics | - | 15 | ||
| Phase angle (o) - mean | 5.47 (SD ±1.0) | 5.16 (SD ±0.9) | 0.11 | |
| Illness marker - mean | 0.807 (SD ± 0.036) | 0.825 (SD ± 0.049) | 0.02 | |
| Dry lean body mass (kg) - mean | 12.97 (SD ± 4.5) | 12.65 (SD ± 4.6) | 0.72 | |
| Rectum | 113 | 24 | ||
| Tumor site | Colon | 47 | 13 | 0.09 |
| Rectum + Colon | 1 | 2 | ||
| 0 | 3 | 0 | ||
| 1 | 21 | 6 | ||
| Stage TNM | II | 33 | 0.50 | |
| III | 91 | 18 | ||
| IV | 13 | 6 | ||
| Preoperative radiotherapy | No | 67 | 18 | |
| Yes | 94 | 21 | 0.61 | |
| Preoperative chemotherapy | No | 90 | 22 | |
| Yes | 71 | 17 | 0.95 | |
| Surgical procedure | Low anterior resection | 73 | 13 | |
| Miles + Hartman | 38 | 12 | 0.38 | |
| Colon resection | 50 | 14 | ||
| Synchronous resection of liver metastases | No | 151 | 35 | 0.48 |
| Yes | 10 | 4 | ||
| Duration of surgery (min) - mean | 175 (SD ±66) | 199 (SD ±64) | 0.034 | |
| Loss of blood (mL) -mean | 584 (SD ±497) | 813 (SD ±812) | 0.027 | |
| Postoperative transfusion of | ||||
| packed red blood cells (mL) | 351 (SD ±516) | 603 (SD ±665) | 0.011 | |
| -mean | ||||
| Postoperative infection (any site) | No | 110 | 22 | 0.16 |
| Yes | 51 | 17 | 0.16 | |
| Re-operation | No | 153 | 35 | 0.21 |
| Yes | 8 | 4 | 0.21 | |
| Hospital stay (days) -mean | 14.4 (SD ±7.6) | 19.9 (SD ±10.6) | 0.028 | |
| No | 111 | 28 | ||
| Locoregional | 4 | 1 | 0.63 | |
| Recurrence (N = 181) | Distant | 26 | 3 | |
| Locoregional + distant | 7 | 1 | ||
| Alive | 117 | 30 | ||
| Dead of disease | 34 | 7 | ||
| Outcome | Dead of other causes | 9 | 1 | 0.74 |
| Dead - Unknown cause | 1 | 1 |