Figure 1
Baseline characteristics
| Characteristics | n (%) |
|---|---|
| Gender | |
| Female / Male | 92 (58) / 66 (42) |
| Age (years) | |
| Mean ± SD / median / range | 67.1 ± 9.8 / 68 / 34-85 |
| Comorbidity | |
| Diabetes / Cardiovascular disease | 13 (8) / 40 (25) |
| Smoking | |
| Yes / No | 87 (55) / 71 (45) |
| Obesity | |
| Yes / No | 31 (20) / 127 (80) |
| Preoperative radiotherapy | |
| Yes / No | 65 (41) / 93 (59) |
| Operating time (minutes) | |
| Mean ± SD / median / range | 118.9 ± 24.8 / 120 / 45-190 |
| Level of anastomosis (cm) | |
| Mean ± SD / median / range | 5.4 ± 1.1 / 5.0 / 3-7 |
| Blood transfusion | |
| Yes / No | 24 (15) / 134 (85) |
| Postoperative fever | |
| Yes / No | 9 (6) / 149 (94) |
| T stage | |
| T1T2 / T3 | 95 (60) / 63 (40) |
| N status | |
| N- / N+ | 91 (58) / 67 (42) |
Uni – and multivariate analysis of anastomotic leakage incidence
| Patients with | Univariate | Multivariate | |
|---|---|---|---|
| Variables | leakage | analysis | analysis |
| n (%) | P - value | P - value | |
| Gender | |||
| Female | 2 (2.2) | 0.4010 | - |
| Male | 3 (4.5) | ||
| Age | |||
| ≥ 75 | 4 (12.5) | 0.0007 | 0.0004 |
| < 75 years | 1 (0.8) | ||
| Diabetes | |||
| Yes | 1 (7.7) | ||
| No | 4 (2.8) | 0.3303 | - |
| Cardiovascular disease | |||
| Yes | 1 (2.5) | ||
| No | 4 (3.4) | 0.7811 | - |
| Smoking | |||
| Yes | 5 (5.7) | ||
| No | 0 (0) | 0.0401 | 0.043 |
| Obesity | |||
| Yes | 2 (6.5) | ||
| No | 3 (2.4) | 0.2435 | - |
| Preoperative radiotherapy | |||
| yes | 3 (4.6) | ||
| no | 2 (2.2) | 0.4053 | - |
| Level of anastomosis | |||
| > 5 | 1 (1.5) | ||
| ≤ 5 cm | 4 (4.3) | 0.3289 | - |
| Blood transfusion | |||
| yes | 1 (4.2) | ||
| no | 4 (3.0) | 0.7607 | - |
| Postoperative fever | |||
| yes | 0 (0) | ||
| no | 5 (3.4) | 0.5765 | - |
| T stage | |||
| T1T2 | 3 (3.1) | ||
| T3 | 2 (3.2) | 0.9953 | - |
| N status | |||
| N- | 3 (3.3) | ||
| N+ | 2 (3.0) | 0.9119 | - |