Figure 1

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Figure 7

Characteristics of control patients
| Parameters | Data |
|---|---|
| Control group | |
| Number of patients | 34 |
| Age (years, value ± SEM) | 41.97 ± 1.68 |
| Age range (years) | 21-69 |
| Elevated CA125 (U/mL) | |
| n (%) | 0 |
| Value (mean ± SEM) | NA |
| sOPN (ng/mL) | |
| Serum (mean ± SEM) | 28.12 ± 2.10 |
| Peritoneal fluid (mean ± SEM) | 132.02 ± 7.85 |
| Benign diagnosis, n (%) | |
| Benign ovarian cyst | 6 (17 %) |
| Myoma of uterus | 21 (62 %) |
| Pelvic pain, sterilisation | 5 (15 %) |
| Preventive adnexectomy | 2 (6 %) |
| Peritoneal fluid (mL) | |
| Volume (mean ± SEM) | 8.04 ± 1.22 |
Comparison between ovarian cancer patients’ characteristics who underwent primary debulking surgery and those considered candidates for neoadjuvant chemotherapy (= diagnostic laparoscopy as primary event)
| Data | ||
|---|---|---|
| Parameters | Primary event: | Primary event: |
| Number of patients | 13 | 18 |
| Age (years, value ± SEM) | 57.61 ± 3.27 | 62 ± 2.45 |
| Age range (years) | 41-76 | 45-85 |
| Elevated CA125 (U/mL) | ||
| n (%) | 13 (100 %) | 18 (100 %) |
| Value (mean ± SEM) | 3936 ± 1568 | 3904 ± 1972 |
| sOPN (ng/mL) | ||
| Serum (mean ± SEM) | 70.48 ± 9.95 | 102 ± 11.53 |
| Ascites (mean ± SEM) | 2154 ± 479.7 | 4515 ± 657.3 |
| Histological type, n (%) | ||
| Serous | 10 (77 %) | 17 (94 %) |
| Endometrioid | 2 (15 %) | 1 (6 %) |
| Serous + clear cell | 1 (8 %) | 0 (0 %) |
| FIGO stage, n (%) | ||
| IIIB | 1 (8 %) | 0 (0 %) |
| IIIC | 11 (84 %) | 11 (61 %) |
| IV | 1 (8 %) | 7 (39 %) |
| Histological grade, n (%) | ||
| G1 | 0 (0 %) | 2 (11 %) |
| G2 | 5 (38 %) | 7 (39 %) |
| G3 | 8 (62 %) | 9 (50 %) |
| Ascites (mL) | ||
| Volume (mean ± SEM) | 1779 ± 728.4 | 3916 ± 614.7 |
| Resection, n (%) | * | |
| R0 | 5 (38 %) | 9 (50 %) |
| R1 | 5 (38 %) | 1 (6 %) |
| R2 | 3 (24 %) | 0 (0 %) |
| Unresectable | 0 (0 %) | 8 (44 %) |