Interval cancers after negative immunochemical test compared to screen and non-responders’ detected cancers in Slovenian colorectal cancer screening programme

Dominika Novak Mlakar; Tatjana Kofol Bric; Ana Lucija Škrjanec; Mateja Krajc

doi:10.2478/raon-2018-0025

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Interval cancers after negative immunochemical test compared to screen and non-responders’ detected cancers in Slovenian colorectal cancer screening programme

Radiology and Oncology

Volume 52 (2018): Issue 4 (December 2018)

By: Dominika Novak Mlakar, Tatjana Kofol Bric, Ana Lucija Škrjanec and Mateja Krajc

Open Access

|Jul 2018

Figures & Tables

Colorectal cancer screening flowchart, including screen detected, interval and non-responders’ cancers.

Test sensitivity adjusted for selection bias according to the proportional incidence method formula.

Selected characteristics of colorectal cancer patients and their disease

		Screen detected cancer (SDC)		Interval cancer (IC)		Non-responders cancer (NRC)		p value (SDC vs IC)	p value (IC vs NRC)	p value (SDC vs NRC)

		Number	%	Number	%	Number	%
Cancer total		493		79		395
Age	50-54	89	18.1	12	15.2	73	18.5	0.101	0.323	0.119
	55-59	93	18.9	10	12.7	63	15.9
	60-64	182	36.9	26	32.9	145	36.7
	65 ≤	129	26.2	31	39.2	114	28.9
Gender	Male	308	62.5	50	63.3	271	68.6	0.889	0.356	0.057
Gender	Female	185	37.5	29	36.7	124	31.4	0.889	0.356	0.057
Years of schooling	≤ 9 years	146	29.6	14	17.7	160	40.5	0.029	< 0.001	0.001
	≥ 10 years	342	69.4	64	81.0	230	58.2
	Unknown	5	1.0	1	1.3	5	1.3
Cancer site	Distal colon	380	77.1	39	49.4	301	76.2	< 0.001	< 0.001	0.759
Cancer site	Proximal colon	113	22.9	40	50.6	94	23.8	< 0.001	< 0.001	0.759
TNM stage	I	251	50.9	16	20.3	32	8.1	< 0.001	0.023	< 0.001
	II	99	20.1	17	21.5	87	22.0
	III	104	21.1	25	31.6	124	31.4
	IV	39	7.9	19	24.1	132	33.4
	Unknown	0		2	2.5	20	5.1

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DOI: https://doi.org/10.2478/raon-2018-0025 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099

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Language: English

Page range: 413 - 421

Submitted on: Apr 17, 2018

Accepted on: May 20, 2018

Published on: Jul 12, 2018

Published by: Association of Radiology and Oncology

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

colorectal cancer screening,

faecal immunochemical test,

interval cancer,

screen detected cancer,

cancer in non-responders,

Related subjects:

Haematology, oncology,

Radiology

© 2018 Dominika Novak Mlakar, Tatjana Kofol Bric, Ana Lucija Škrjanec, Mateja Krajc, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Volume 52 (2018): Issue 4 (December 2018)

Interval cancers after negative immunochemical test compared to screen and non-responders’ detected cancers in Slovenian colorectal cancer screening programme

Figures & Tables

Figure 1

Figure 2

Selected characteristics of colorectal cancer patients and their disease

Paradigm

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