Figure 1
Multivariate model for wall calcinations and/or plaque
| Odds ratio (95%CI) | p value | |
|---|---|---|
| Smoking | 2.765 (0.680–1.238) | 0.155 |
| Age at evaluation (years) | 1.081 (0.974–1.201) | 0.144 |
Risk factors in controls and cancer survivors
| Charasteristics and risk factors | Controls | Survivors | P value |
|---|---|---|---|
| Total | 26 | 23 | |
| Sex (male (%)) | 6 (77) | 7 (70) | 0.40 |
| Smoking (%) | 8 (30.8) | 7 (30.4) | 0.613 |
| Family history (%) | 5 (20) | 0 | 0.031 |
| Arterial hypertension (%) | 4 (15.4) | 6 (26.1) | 0.354 |
| Diabetes mellitus | 0 | 0 | |
| Age (years) | 42.65 ± 5.38 | 40.22 ± 6.56 | 0.16 |
| Total cholesterol (mmol/l) | 5.7 ± 1.00 | 5.6 ± 1,01 | 0.646 |
| Body mass index | 25.4 ± 2.98 | 24.9 ± 1.85 | 0.595 |
Multivariate model for carotid pulse-wave velocity (PWV)
| Estimate (SE) | p value | |
|---|---|---|
| Sex | -0.538 (0.471) | 0.261 |
| Smoking | 0.937 (0.436) | 0.031 |
| Age at evaluation (years) | -0.050 (0.034) | 0.155 |
| RT (2 groups Size of RT dose (higher than 30 Gy or lower/equal to 30 Gy) | -0.622 (0.439) | 0.165 |
T-test for IMT and stiffness parameters
| Group | N | Mean | Sth. dev. | P value | |
|---|---|---|---|---|---|
| IMT | 0 | 52 | 0.546 | 0.056 | 0.92 |
| 1 | 43 | 0.548 | 0.132 | ||
| Beta stiffness | 0 | 52 | 6.732 | 1.437 | 0.008 |
| 1 | 43 | 8.014 | 3.035 | ||
| Ep | 0 | 52 | 88.149 | 20.348 | 0.008 |
| 1 | 43 | 109.767 | 53.331 | ||
| AC | 0 | 52 | 0.774 | 0.264 | 0.034 |
| 1 | 43 | 0.651 | 0.293 | ||
| AI | 0 | 52 | 6.722 | 6.820 | 0.000 |
| 1 | 43 | 20.130 | 12.833 | ||
| PWV | 0 | 52 | 5.733 | 0.702 | 0.009 |
| 1 | 43 | 6.300 | 1.334 |
Univariate model for carotid pulse-wave velocity (PWV) and wall calcinations and/or plaque
| PWV | Wall calcinations and/or plaque | |||
|---|---|---|---|---|
| Linear regression estimate (SE) | p value | Odds ratio (95%CI) | p value | |
| Gender | 0.055 (0.448) | 0.03 | 1.121 (0.303–4.145) | 0.864 |
| Smoking | 0.741 (0.424) | 0.088 | 2.679 (0.681–10.534) | 0.158 |
| Arterial hypertension | -0.037 (0.472) | 0.938 | 0.570 (0.143–2.268) | 0.425 |
| Age at Dg (years) | 0.019 (0.052) | 0.718 | 1.094 (0.936–1.278) | 0.258 |
| Age at evaluation (years) | -0.047 (0.032) | 0.151 | 1.078 (0.975–1.192) | 0.143 |
| Total cholesterol | 0.021 (0.205) | 0.920 | 0.702 (0.381–1.294) | 0.257 |
| Body mass index | 0.021 (0.118) | 0.862 | 0.926 (0.655–1.309) | 0.664 |
| Chemo (yes/no) | 0.365 (0.484) | 0.455 | 0.455 (0.100–2.072) | 0.309 |
| RT (2 groups Size of radiotherapy dose (higher than 30 Gy or lower/equal to 30 Gy) | -0.551 (0.431) | 0.208 | 1.680 (0.452–6.249) | 0.439 |