Clonality analysis of lymphoid proliferations using the BIOMED-2 clonality assays: a single institution experience
References
- 1. Sandberg Y, van Gastel-Mol EJ, Verhaaf B, Lam KH, van Dongen JJ, Langerak AW. BIOMED-2 multiplex immunoglobulin/T-cell receptor polymerase chain reaction protocols can reliably replace Southern blot analysis in routine clonality diagnostics. J Mol Diagn 2005;495-503.
- 2. Hoeve MA, Krol AD, Philippo K, Derksen PW, Veenendaal RA, Schuuring E, et al. Limitations of clonality analysis of B cell proliferations using CDR3 polymerase chain reaction. J Clin Pathol Mol Pathol 2000;194-200.
- 3. van Krieken JH, Langerak AW, Macintyre EA, Kneba M, Hodges E, Garcia Sanz R, et al. Improved reliability of lymphoma diagnostics via PCR-based clonality testing: - Report of the BIOMED-2 concerted action BHM4-CT98-3936. Leukemia 2007;201-6.
- 4. McCarthy KP, Sloane JP, Wiedemann LM. Rapid method for distinguishing clonal from polyclonal B cell populations in surgical biopsy specimens. J Clin Pathol 1990;429-32.
- 5. Trainor KJ, Brisco MJ, Wan JH, Neoh S, Grist S, Morley AA. Gene rearrangement in B- and T-lymphoproliferative disease detected by the polymerase chain reaction. Blood 1991;192-5.
- 6. Slack DN, McCarthy KP, Wiedemann LM, Sloane JP. Evaluation of sensitivity, specificity and reproducibility of an optimized method for detecting clonal rearrangements of immunoglobulin and T-cell receptor genes in formalinfixed, paraffin-embedded sections. Diagn Mol Pathol 1993;223-32.
- 7. Segal GH, Jorgensen T, Masih AS, Braylan TC. Optimal primer selection for clonality assessment by polymerase chain reaction analysis: I. Low grade B-cell lymphoproliferative disorders of nonfollicular center cell type. Hum Pathol 1994;1269-75.
- 8. Davis TH, Courtland EY, Balk SP. Detection of clonal immunoglobulin gene rearrangements by polymerase chain reaction amplification and single-strand conformational polymorphism analysis. Am J Pathol 1993;1841-47.
- 9. Chen YT, Whitney KD, Chen Y. Clonality analysis of B-cell lymphoma in freshfrozen and paraffin-embedded tissues: The effects of variable polymerase chain reaction parameters. Mod Pathol 1994;429-34.
- 10. McCarthy KP, Sloane JP, Wiedemann LM. A simplified method of detection of clonal rearrangements of the T-cell receptor g chain gene. Diagn Mol Pathol 1992;173-79.
- 11. Theodorou I, Raphael M, Bigorgne C, Fourcade C, Lahet C, Cochet G, et al. Recombination pattern of the TCRg locus in human peripheral T-cell lymphomas. J Pathol 1994;233-42.
- 12. Diss TC, Watts M, Pan LX, Burke M, Linch D, Isaacson PG. The polymerase chain reaction in the demonstration of monoclonality in T cell lymphomas. J Clin Pathol 1995;1045-50.
- 13. Liu H, Bench AJ, Bacon CM, Payne K, Huang Y, Scott MA, et al. A practical strategy for the routine use of BIOMED-2 PCR assays for detection of B- and T-cell clonality in diagnostic haematopathology. Br J Haematol 2007;31-43.
- 14. van Dongen JJ, Langerak AW, Brüggemann M, Evans PA, Hummel M, Lavender FL, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptore gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia 2003;2257-317.
- 15. Evans PA, Pott C, Groenen PJ, Salles G, Davi F, Berger F, et al. Significantly improved PCR-based clonality testing in B-cell malignancies by use of multiple immunoglobulin gene targets. Report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia 2007;207-14.
- 16. Brüggemann M, White H, Gaulard P, Garcia-Sanz R, Gameiro P, Oeschger S, et al. Powerful strategy for polymerase chain reaction-based clonality assessment in T-cell malignancies. Report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia 2007;215-21.
- 17. Langerak AW, Molina TJ, Lavender FL, Pearson D, Flohr T, Sambade C, et al. Polymerase chain reaction-based clonality testing in tissue samples with reactive lymphoproliferations: usefulness and pitfalls. A report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia 2007;222-29.
- 18. Langerak AW, Groenen PJ, van Krieken JH, van Dongen JJ. Immunoglobulin/Tcell receptor clonality diagnostics. Expert Opin Med Diagn 2007;451-61.
- 19. Groenen PJ, Langerak AW, van Dongen JJ, van Krieken JH. Pitfalls in TCR gene clonality testing: teaching cases. J Hematopathol 2008;97-109.
- 20. Matthews C, Catherwood M, Morris TC, Alexander HD. Routine analysis of IgHV mutational status in CLL patients using BIOMED-2 standardized primers and protocols. Leuk Lymphoma 2004;1899-904.
- 21. Dawidovska M, Jólkowska J, Sczepański T, Derwich K, Wachowiak J, Witt M. Implementation of the standard strategy for identification of Ig/TCR targets for minimal residual disease diagnostics in B-cell precursor ALL pediatric patients: Polish experience. Arch Immunol Ther Exp 2008;409-18.
- 22. Chen YL, Su IJ, Cheng HY, Chang KC, Lu CC, Chow NH, et al. BIOMED-2 protocols to detect clonal immunoglobulin and T-cell receptor gene rearrangements in B- and T-cell lymphomas in southern Taiwan. Leuk Lymphoma 2010;650-55.
- 23. Lassmann S, Gerlach UV, Technau-Ihling K, Werner M, Fisch P. Application of BIOMED-2 primers in fixed and decalcified bone marrow biopsies: analysis of immunoglobulin H receptor rearrangements in B-cell non-Hodgkin’s lymphomas. J Mol Diagn 2005;582-91.
- 24. Lukowsky A, Marchwat M, Sterry W, Gellrich S. Evaluation of B-cell clonality in archival skin biopsy samples of cutaneous B-cell lymphoma by immunoglobulin heavy chain gene polymerase chain reaction. Leuk Lymphoma 2006;487-93.
- 25. Hebeda KM, van Altena MC, Rombout P, van Krieken JH, Groenen PJ. PCR clonality detection in Hodgkin lymphoma.2009;:34-41.
- 26. Burack WR, Laughlin TS, Friedberg JW, Spence JM, Rothberg PG. PCR assays detect B-lymphocyte clonality in formalin-fixed, paraffin-embedded specimens of classical Hodgkin lymphoma without microdissection. Am J Clin Pathol 2010;104-11.
- 27. Zhang S, Abreo F, Lowery-Nordberg M, Veillon DM, Cotelingam JD. The role of fluorescence in situ hybridization and polymerase chain reaction in the diagnosis and classification of lymphoproliferative disorders on fine-needle aspiration. Cancer Cytopathol 2010;105-12.
- 28. Payne K, Wright P, Grant JW, Huang Y, Hamoudi J, Bacon CM, et al. BIOMED-2 PCR assays for IGK gene rearrangements are essential for B-cell clonality analysis in follicular lymphoma. Br J Haematol 2011;84-92.
- 29. Berget E, Helgeland L, Molven A, Vintermyr OK. Detection of clonality in follicular lymphoma using formalin-fixed, paraffin-embedded tissue samples and BIOMED-2 immunoglobulin primers. J Clin Pathol 2011;37-41.
- 30. Sandberg Y, Heule F, Lam K, Lugtenburg PJ, Wolvers-Tettero IL, van Dongen JJ, et al. Molecular immunoglobulin/T-cell receptor clonality in cutaneous lymphoproliferations. Experience with the BIOMED-2 standardized polymerase chain reaction protocol. Haematologica 2003;659-70.
- 31. Catherwood MA, Gonzales D, Patton C; Dobbin E, Venkatraman L, Alexander HD. Improved clonality assessment in germinal centre/post germinal centre non- Hodgkin’s lymphomas with high rates of somatic hypermutation. J Clin Pathol 2007;524-28.
- 32. Tan BT, Seo K, Warnke RA, Arber DA. The frequency of immunoglobulin heavy chain gene and T-cell receptor g-chain gene rearrangements and Epstein-Barr virus in ALK+ and ALK- anaplastic large cell lymphoma and other peripheral T-cell lymphomas. J Mol Diagn 2008;502-12.
- 33. Zhang B, Beck AH, Taube JM, Kohler S, Seo K, Zwerner J, et al. Combined use of PCR-based TCRG and TCRB clonality tests on paraffin-embedded skin tissue in the differential diagnosis of Mycosis fungoides and inflammatory dermatoses. J Mol Diagn 2010;320-27.
- 34. Nakamichi N, Wada N, Kohara M, Fukuhara S, Sugiyama H, Ogawa H, et al. Polymorphous lymphoproliferative disorder: a clinicopathological analysis.Virchows Arch 2010;269-76.
- 35. Dabiri S, Morales A, Ma L, Sundram U, Kim YH, Arber DA, et al. The frequency of dual TCR-PCR clonality in granulomatous disorders. J Cutan Pathol 2011;704-9.
- 36. McClure RF, Kaur P, Pagel E, Ouillette PD, Holtegaard CE, Treptow CL, et al. Validation of immunoglobulin gene rearrangement detection by PCR using commercially available BIOMED-2 primers. Leukemia 2006;176-79.
- 37. Patel KP, Pan Q, Wang Y, Maitta RW; Du J, Xue X, et al. Comparison of BIOMED-2 versus laboratory-developed polymerase chain reaction assays for detecting T-cell receptor-g gene rearrangements. J Mol Diagn 2010;226-37.
- 38. Zaki MA, Wada N, Kohara M, Ikeda J, Hori Y, Fujita S, et al. Presence of B-cell clones in T-cell lymphoma. Eur J Haematol 2011;412-19.
- 39. Langerak AW, Groenen PJ, Brüggemann M, Beldjord K, Bellan C, Bonello L, et al. EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferations.2012;2159-71.
- 40. Jaffe ES, Harris NL, Stein H and Vardiman JW: Tumours of Haematopoietic and Lymphoid Tissues. In:Lyon: IARC Press; 2001.
- 41. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al.Lyon: IARC Press; 2008.
- 42. Diss TC, Peng H, Wotherspoon AC, Isaacson PG, Pan L. Detection of monoclonality in low-grade B-cell lymphomas using the polymerase chain reaction is dependent on primer selection and lymphoma type. J Pathol 1993;291-95.
- 43. Posnett DN, Sinha R, Kabak S, Russo C. Clonal populations of T cells in normal elderly humans: the T cell equivalent to “benign monoclonal gammapathy”. J Exp Med 1994;609-18.
- 44. Delfau-Larue MH, Laroche L, Wechsler J, Lepage E, Lahet C, Asso-Bonnet M, et al. Diagnostic value of dominant T-cell clones in peripheral blood in 363 patients presenting consecutively with a clinical suspicion of cutaneous lymphoma. Blood 2000;2987-92.
- 45. Godges E, Krishna MT, Pickard C, Smith JL. Diagnostic role of test for T cell receptor (TCR) genes. J Clin Pathol 2003;1-11.
Language: English
Page range: 155 - 162
Submitted on: May 9, 2013
Accepted on: Oct 1, 2013
Published on: Apr 25, 2014
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
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© 2014 Ira Kokovic, Barbara Jezersek Novakovic, Petra Cerkovnik, Srdjan Novakovic, published by Association of Radiology and Oncology
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