Skip to main content
Have a personal or library account? Click to login
Inhibition of cathepsin X enzyme influences the immune response of THP-1 cells and dendritic cells infected with Helicobacter pylori Cover

Inhibition of cathepsin X enzyme influences the immune response of THP-1 cells and dendritic cells infected with Helicobacter pylori

Open Access
|Jul 2013

References

  1. 1. Rad R, Ballhorn W, Voland P, Eisenächer K, Mages J, Rad L, et al. Extracellular and intracellular pattern recognition receptors cooperate in the recognition of.2009;2247-57.
  2. 2. Amieva MR, El-Omar EM. Host-bacterial interactions ininfection2008;306-23.
  3. 3. Borody T, Ren Z, Pang G, Clancy R. Impaired host immunity contributes toeradication failure2002;3032-7.
  4. 4. Mitchell P, Germain C, Fiori PL, Khamri W, Foster GR, Ghosh S, et al. Chronic exposure toimpairs dendritic cell function and inhibits Th1 development.2007;810-7.
  5. 5. Bühling F, Peitz U, Krüger S, Küster D, Vieth M, Gebert I et al. Cathepsins K, L ,B , X and W are differentially expressed in normal and chronically inflamed gastric mucosa.2004;439-45.
  6. 6. Krueger S, Kuester D, Bernhardt A, Wex T, Roessner A. Regulation of cathepsin X overexpression in-infected gastric epithelial cells and macrophages.2009;581-8.
  7. 7. Krueger S, Hundertmark T, Kalinski T, Peitz U, Wex T, Malfertheiner P, et al. Up-regulation of cathepsinX ingastritis and gastric cancer.2005;32-42.
  8. 8. Kos J, Sekirnik A, Premzl A, Zavasnik Bergant V, Langerholc T, Turk B, et al. Carboxypeptidases cathepsins X and B display distinct protein profile in human cells and tissues.2005;103-13.
  9. 9. Obermajer N, Premzl A, Zavasnik Bergant T, Turk B, Kos J. Carboxypeptidase cathepsin X mediates beta2-integrin-dependent adhesion of differentiated U-937 cells.2006;2515-27.
  10. 10. Obermajer N, Svajger U, Bogyo M, Jeras M, Kos J. Maturation of dendritic cells depends on proteolytic cleavage by cathepsinX.2008;1306-15.
  11. 11. Jevnikar Z, Obermajer N, Bogyo M, Kos J. The role of cathepsin X in the migration and invasiveness of T lymphocytes.2008;2652-61.
  12. 12. Achtman M, Azuma T, Berg DE, Ito Y, Morelli G, Pan ZJ, et al. Recombination and clonal groupings withinfrom different geographical regions.1999;459-70.
  13. 13. Kopitar AN, Stegel V, Tepes B, Gubina M, Novaković S, Ihan A. Specific T cell responses topredict successful eradication therapy.2007;257-61.
  14. 14. Obermajer N, Magister S, Kopitar AN, Tepes B, Ihan A, Kos J. Cathepsin X prevents an effective immune response againstinfection.2009;461-71.
  15. 15. Cario E, Brown D, McKee M, Lynch-Devaney K, Gerken G, Podolsky DK. Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium.2002;165-73.
  16. 16. Hornef MW, Frisan T, Vandewalle A, Normark S, Richter-Dahlfors A. Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cells.2002;559-70.
  17. 17. Wang X, Uto T, Sato K, Ide K, Akagi T, Okamoto M, et al. Potent activation of antigen-specific T cells by antigen-loaded nanospheres.2005;123-30.
  18. 18. Robinson K, Kenefeck R, Pidgeon EL, Shakib S, Patel S, Polson RJ, et al.-induced peptic ulcer disease is associated with inadequate regulatory T cell responses2008;1375-85.
  19. 19. Zhang M, Liu M, Luther J, Kao JY.directs tolerogenic programming of dendritic cells.2010;325-9.
  20. 20. Kos J, Jevnikar Z, Obermajer N. The role of cathepsin X in cell signaling.2009;164-6.
  21. 21. Kraus S, Bunsen T, Schuster S, Cichoń MA, Tacke M, Reinheckel T, et al. Cellular senescence induced by cathepsin X downregulation.2011;678-86.
  22. 22. Higgins SC, Lavelle EC, McCann C, Keogh B, McNeela E, Byrne P, et al. Toll like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance toby inhibiting inflammatory pathology.2003;3119-27.
  23. 23. Kurashima Y, Murata-Kamiya N, Kikuchi K, Higashi H, Azuma T, Kondo S, et al. Deregulation of beta-catenin signal byCagA requires the CagA-multimerization sequence.2008;823-31.
  24. 24. Sugimoto M, Yamaoka Y. Virulence factor genotypes ofaffect cure rates of eradication therapy.2009;45-56.
  25. 25. Patel MK, Trombly MI, Kurt-Jones EA. Innate immune responses to Helicobacter pylori infection: an overview.2012;205-7.
  26. 26. Vizin T, Christensen IJ, Nielsen HJ, Kos J. Cathepsin X in serum from patients with colorectal cancer: relation to prognosis.. 2012;207-12.
  27. 27. Sevenich L, Schurigt U, Sachse K, Gajda M, Werner F, Müller S et al. Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.. 2010;2497-502.
DOI: https://doi.org/10.2478/raon-2013-0043 | Journal eISSN: 1581-3207 | Journal ISSN: 1318-2099
Language: English
Page range: 258 - 265
Published on: Jul 30, 2013
Published by: Association of Radiology and Oncology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2013 Miha Skvarc, David Stubljar, Andreja Natasa Kopitar, Samo Jeverica, Bojan Tepes, Janko Kos, Alojz Ihan, published by Association of Radiology and Oncology
This work is licensed under the Creative Commons License.