Breaking The Stone: Stentless Coronary Revascularization with Intravascular Lithotripsy and Drug-Coated Balloon Technology Guided by IVI
References
- Kereiakes DJ, Virmani R, Hokama JY, et al. Principles of Intravascular Lithotripsy for Calcific Plaque Modification. JACC Cardiovasc Interv. 2021 Jun 28;14(12):1275-1292. doi: 10.1016/j.jcin.2021.03.036. PMID: 34167671.
- Lee MS, Kereiakes DJ, Shlofmitz RA, et al. Intravascular Lithotripsy for Calcified Left Main Artery Disease. J Soc Cardiovasc Angiogr Interv. 2023 Aug 25;2(6Part A):101126. doi: 10.1016/j.jscai.2023.101126. PMID: 39129890; PMCID: PMC11308112.
- Hill JM, Kereiakes DJ, Shlofmitz RA, et al; Disrupt CAD III Investigators. Intravascular Lithotripsy for Treatment of Severely Calcified Coronary Artery Disease. J Am Coll Cardiol. 2020 Dec 1;76(22):2635-2646. doi: 10.1016/j. jacc.2020.09.603. Epub 2020 Oct 15. PMID: 33069849.
- Rosenberg M, Waliszewski M, Chin K, et al. Prospective, large-scale multicenter trial for the use of drug-coated balloons in coronary lesions: The DCB-only All-Comers Registry. Catheter Cardiovasc Interv. 2019 Feb 1;93(2):181-188. doi: 10.1002/ccd.27724. Epub 2018 Oct 2. PMID: 30280482.
- Tao L, He X, Shen G, et al; REC-CAGEFREE I Investigators. Drug-Coated Balloon Angioplasty vs Up-Front Stenting for De Novo CAD: 3-Year Follow-Up of REC-CAGE-FREE I Trial. J Am Coll Cardiol. 2025 Oct 27:S0735-1097(25)09986-3. doi: 10.1016/j. jacc.2025.10.027. Epub ahead of print. PMID: 41194754.
- Sogabe K, Koide M, Fukui K, et al. Optical coherence tomography analysis of late lumen enlargement after paclitaxel-coated balloon angioplasty for de-novo coronary artery disease. Catheter Cardiovasc Interv. 2021 Jul 1;98(1):E35-E42. doi: 10.1002/ccd.29435. Epub 2020 Dec 28. PMID: 33369836.
- Megaly M, Buda K, Saad M, et al. Outcomes With Drug-Coated Balloons vs. Drug-Eluting Stents in Small-Vessel Coronary Artery Disease. Cardiovasc Revasc Med. 2022 Feb;35:76-82. doi: 10.1016/j.carrev.2021.03.008. Epub 2021 Mar 20. PMID: 33858783.
- Stone GW, Genereux P, Maehara A, et al. Intravascular Imaging vs Angiography Guidance for PCI of Severely Calcified Lesions: The ECLIPSE Trial. JACC Cardiovasc Interv. 2025 Oct 13;18(19):2338-2351. doi: 10.1016/j. jcin.2025.08.024. PMID: 41093451.
- Carvalho PEP, Antunes VLJ, Bittar de Pontes V, et al. IVUS, OCT, or Angiography as Guidance for PCI in Complex Coronary Artery Lesions: Network Meta-Analysis of Randomized Controlled Trials. JACC Cardiovasc Interv. 2026 Jan 12;19(1):31-43. doi: 10.1016/j. jcin.2025.11.021. PMID: 41534986.
- Misawa T, Lee T, Ashikaga T, et al. Clinical outcomes of stent-less percutaneous coronary intervention with intravascular lithotripsy and drug-coated balloon for severely calcified de novo coronary lesions. Int J Cardiol Heart Vasc. 2025 May 27;59:101707. doi: 10.1016/j. ijcha.2025.101707. PMID: 40503435; PMCID: PMC12158476.
- Randomised comparison of intravascular lithotripsy vs. cutting balloon treatment in calcified coronary artery disease – The Short-CUT trial. Late-breaking trial TCT 2025. https://www.clinicaltrials.gov/study/NCT06089135
- A randomised, multicenter, non-inferiority comparison of intravascular lithotripsy and super-high-pressure non-compliant balloons for treatment of calcified and refractory coronary lesions - The VICTORY trial. [Online] Late-breaking trial TCT 2025.
- Visinoni ZM, Jurewitz DL, Kereiakes DJ, et al. Coronary intravascular lithotripsy for severe coronary artery calcification: The Disrupt CAD I-IV trials. Cardiovasc Revasc Med. 2024 Aug;65:81-87. doi: 10.1016/j.carrev.2024.03.001. Epub 2024 Mar 3. PMID: 38472025.
- Jeger RV, Eccleshall S, Wan Ahmad WA, et al; International DCB Consensus Group. Drug-Coated Balloons for Coronary Artery Disease: Third Report of the International DCB Consensus Group. JACC Cardiovasc Interv. 2020 Jun 22;13(12):1391-1402. doi: 10.1016/j.jcin.2020.02.043. Epub 2020 May 27. PMID: 32473887.
- Rissanen TT, Uskela S, Eränen J, et al; DEBUT trial investigators. Drug-coated balloon for treatment of de-novo coronary artery lesions in patients with high bleeding risk (DEBUT): a single-blind, randomised, non-inferiority trial. Lancet. 2019 Jul 20;394(10194):230-239. doi: 10.1016/S0140-6736(19)31126-2. Epub 2019 Jun Erratum in: Lancet. 2019 Jul 20;394(10194):218. doi: 10.1016/S0140-6736(19)31464-3. PMID: 31204115.
- Hong SJ, Lee SJ, Lee SH, et al; OCCUPI investigators. Optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention for patients with complex lesions (OCCUPI): an investigator-initiated, multicentre, randomised, open-label, superiority trial in South Korea. Lancet. 2024 Sep 14;404(10457):1029-1039. doi: 10.1016/S0140-6736(24)01454-5. Epub 2024 Sep 2. PMID: 39236729.
- Ali ZA, Landmesser U, Maehara A, et al; ILU-MIEN IV Investigators. Optical Coherence Tomography-Guided versus Angiography-Guided PCI. N Engl J Med. 2023 Oct 19;389(16):1466-1476. doi: 10.1056/NEJMoa2305861. Epub 2023 Aug 27. PMID: 37634188.
Language: English
Page range: 55 - 62
Published on: Jun 30, 2026
Published by: Macedonian Academy of Sciences and Arts
In partnership with: Paradigm Publishing Services
Publication frequency: 3 issues per year
Keywords:
Related subjects:
© 2026 Aleksandar Jovkovski, Biljana Zafirovska, Dona Zarevska, Ivan Vasilev, Hajber Taravari, Danica Petkoska, Jorgo Kostov, Sasko Kedev, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.