Have a personal or library account? Click to login

Effect of Supplemental Antioxidant-Based Therapy on the Oxidative Stress Level in COVID-19 Patients

Open Access
|Mar 2023

References

  1. https://covid19.who.int/ -accessed on 27 February 2022
  2. Li C, He Q, Qian H, Liu J. Overview of the pathogenesis of COVID 19 (Review). Exp Ther Med. 2021;22:1011.
  3. Barciszewska AM. Elucidating of oxidative distress in COVID-19 and methods of its prevention. Chemico Biol Interact. 2021;344:109501.
  4. Ntyonga-Pono MP. COVID-19 infection and oxidative stress: an under-explored approach for prevention and treatment. Pan Afr Med J. 2020;35:12.
  5. Gadotti AC, Lipinski AL, Vasconcellos FT, et al. Susceptibility of the patients infected with Sars-Cov2 to oxidative stress and possible interplay with severity of the disease. Free Radic Biol Med. 2021;165:184-190.
  6. Costela-Ruiz VJ, Illescas-Montes R, Puerta-Puerta JM, et al. SARS-CoV-2 infection: The role of cytokines in COVID-19 disease. Cytok Growth Fact Rev.2020;54:62–75.
  7. Laforge M, Elbim C, Frère C, et al. Tissue damage from neutrophil-induced oxidative stress in COVID-19. Nat Rev Immunol. 2020;20:515–516.
  8. Pincemail J, Cavalier E, Charlier C, Cheramy– Bien JP, Brevers E, Courtois A, et al. Oxidative Stress Status in COVID-19 Patients Hospitalized in Intensive Care Unit for Severe Pneumonia. A Pilot Study. Antioxidants. 2021;10:257.
  9. Atanasovska E, Petrusevska M, Zendelovska D, et al. Vitamin D levels and oxidative stress markers in patients hospitalized with COVID-19. Redox Rep. 2021;26:184-189.
  10. Zendelovska D, Atanasovska E, Petrushevska M, et al. Evaluation of oxidative stress markers in hospitalized patients with moderate and severe COVID-19. Rom J Intern Med. 2021;59:375-383.
  11. Petrushevska M, Zendelovska D, Atanasovska E, et al. Presentation of cytokine profile in relation to oxidative stress parameters in patients with severe COVID-19: a case-control pilot study. F1000Res. 2021;10:719.
  12. de Las Heras N, Martín Giménez VM, Ferder L, et al. Implications of Oxidative Stress and Potential Role of Mitochondrial Dysfunction in COVID-19: Therapeutic Effects of Vitamin D. Antioxidants. 2020;9:897.
  13. Carpagnano GE, Di Lecce V, Quaranta VN, et al. Vitamin D deficiency as a predictor of poor prognosis in patients with acute respiratory failure due to COVID-19. J Endocrinol Invest. 2021;44:765-771.
  14. D’Avolio A, Avataneo V, Manca A, et al. 25-Hydroxyvitamin D Concentrations Are Lower in Patients with Positive PCR for SARS-CoV-2. Nutrients. 2020;12:1359.
  15. Cuadrado A, Pajares M, Benito M, et al. Can activation of NRF2 be a strategy against COVID-19? Trends Pharmacol Sci. 2020;41:9.
  16. Gasparello J, D’Aversa E, Papi C, Gambari L, Grigolo B, et al. Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein. Phytomedicine. 2021;87:153583.
  17. Bousquet J, Le Moing V, Blain H, et al. Efficacy of broccoli and glucoraphanin in COVID-19: From hypothesis to proof-of-concept with three experimental clinical cases. World Allergy Organ J. 2020;14(1):100498.
  18. Mahn A, Castillo A. Potential of sulforaphane as a natural immune system enhancer: A review. Moecules.2021;26:752.
  19. Kow CS, Ramachandram DS, Hasan SS. Use of sulforaphane in COVID-19: Clinical trials are needed. Mol Immunol. 2022;145:78-79.
  20. Ter Ellen BM, Kumar ND, Bouma EM, et al. Resveratrol and Pterostilbene Inhibit SARSCoV-2 Replication in Air-Liquid Interface Cultured Human Primary Bronchial Epithelial Cells. Viruses.2021;13:1335.
  21. Liao MT, Wu C, WU SV, et al. Resveratrol as an adjunctive therapy for excessive oxidative stress in aging COVID-19 patients. Antioxidants.2021;10:1440.
  22. Filardo S, Di Pietro M, Mastromarino P, Sessa R. Therapeutic potential of resveratrol against emerging respiratory viral infection. Pharmacol Therap. 2020;214:107613.
  23. Rahmadani LH, Bachari K. Potential therapeutic effects of resveratrol against SARS-CoV-2, Acta virol. 2020;64:276-280.
  24. Xiao Z, Ye Q, Duan X, Xiang T. Network pharmacology reveals that resveratrol can alleviate COVID-19 related hyperinflammation, Dis Markers. 2021;4129993.
  25. Pasquereau S, Nehme Z, Haidar Ahmad S, et al. Resveratrol Inhibits HCoV-229E and SARSCoV-2 Coronavirus Replication In Vitro. Viruses. 2021;23:354.
  26. Seo DJ, Choi C. Antiviral bioactive compounds of mushrooms and their antiviral mechanisms: a review. Viruses. 2021;13:50.
  27. Hetland G, Johnson E, Bernardshaw SV, Grinde, B. Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation. Scand J immunol. 2020;00:12937.
  28. Shahzad F, Anderson D, Najafzadeh M. The antiviral, anti-inflammatory effects of natural medicinal herbs and mushrooms and SARS-CoV-2 infection. Nutrients. 2020;12:2573.
  29. Suwannarach N, Kumla J, Sujarit K, et al. Natural Bioactive Compounds from Fungi as Potential Candidates for Protease Inhibitors and Immunomodulators to Apply for Coronaviruses. Molecules. 2020;25;1800.
  30. Gracian-Alcaide C, Maldonado-Lobon JA, Ortiz-Tikkakoski E, et al. Effects of a combination of elderberry and reishi extracts on the duration and severity of respiratory tract infections in elderly subjects: A randomized controlled trial. Appl Sci. 2020;10:8259.
  31. Habashy NH, Abu-Serie MM. The potential antiviral effect of major royal jelly protein2 and its isoform X1 against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Insight on their sialidase activity and molecular docking. J Funct Foods. 2020;75:104282.
  32. Ismail NF, Zulkifli MF, Ismail WIW. Therapeutic potentials of bee products for treatment of COVID-19. IMJM Med J Malaysia. 2021;21.
  33. Lima WG, Brito JCM, da Cruz Nizer WS. Bee products as a source of promising therapeutic and chemoprophylaxis strategies against COVID-19 (SARS-CoV-2), Phytother res. 2020;1-8.
  34. Todorovic N, Djordjevic N, Pajovic SB. In vitro analyses of antioxidant activity of food supplements GE Kids and Ge132+ Natural™, J Food Nutr Res. 2019;7:355-360.
  35. Immunomodulatory and antioxidant activities of Ge132+ Natural™ ™, VivaCell Biotechnology GmbH (2012) (unpublished results).
  36. Ho HPT, Vo DNK, Lin TY, et al. Ganoderma microsporum immunomodulatory protein acts as a multifunctional broad-spectrum antiviral against SARS-CoV-2 by interfering virus binding to the host cells and spike-mediated cell fusion. Biomed Pharmacother. 2022;155:113766.
  37. Cör Andrejč D, Knez Ž, Knez Marevci M. Anti-oxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview. Front Pharmacol. 2022;13:934982.
  38. Ordonez AA, Bullen CK, Villabona-Rueda AF, et al. Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice. Commun Biol. 2022;5(1):242.
  39. McCreary MR, Schnell PM, Rhoda DA. Randomized Double-blind Placebo-controlled Proof-of-concept Trial of Resveratrol for Out-patient Treatment of Mild Coronavirus Disease (COVID-19). Res Sq [Preprint]. 2021;861831.
  40. van Brummelen R, van Brummelen AC. The potential role of resveratrol as supportive anti-viral in treating conditions such as COVID-19 - A formulator’s perspective. Biomed Pharmacother. 2022;148:112767.
  41. Khongthaw B, Dulta K, Chauhan PK, et al. Lycopene: a therapeutic strategy against coronavirus disease 19 (COVID-19). Inflammopharmacology.2022;1–22.
DOI: https://doi.org/10.2478/prilozi-2023-0002 | Journal eISSN: 1857-8985 | Journal ISSN: 1857-9345
Language: English
Page range: 7 - 16
Published on: Mar 29, 2023
Published by: Macedonian Academy of Sciences and Arts
In partnership with: Paradigm Publishing Services
Publication frequency: 2 times per year

© 2023 Dragica Zendelovska, Emilija Atanasovska, Katerina Spasovska, Meri Kirijas, Kosta Kapsarov, Dejan Jakimovski, Marija Petrushevska, published by Macedonian Academy of Sciences and Arts
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.