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Stroke-associated pneumonia: pathophysiology, diagnosis and management strategies Cover

Stroke-associated pneumonia: pathophysiology, diagnosis and management strategies

Open Access
|Aug 2025

Figures & Tables

Risk factor of SAP_

ModifiableNon-modifiable
Atrial fibrillationAge
HypertensionGender
CHFStroke type
Chronic pulmonary diseaseStroke severity
Renal failureBrain lesion location
Anaemia
Diabetes mellitus
Mechanical ventilation
Nasogastric tube

Components of clinical scoring systems for predicting SAP (20)_

A2DS2ISANAIS-APSKwonPANTHERISChumbler
Sex (male)+1+1 +1
Age (years)+1 (≥75)+3 (60–69)+2 (60–69)+1 (≥65)+1 (60–80)+2 (>70)
+4 (70–79)+5 (70-79) +2 (>80)
+6 (80–89)+7 (≥80)
+8 (≥90)
Mechanical ventilation +1
Atrial fibrillation+1 +1
CHF +3
COPD +3
Current smoking +1
Dysphagia+2 +3+1 +4
Past medical history of pneumonia +4
NIHSS+3 (5–15)+4 (5–15)+2 (5–9)+1 (≥11) +1 (per 3 increase)
+5 (≥16)+8 (16–20)+5 (9–14)
+10 (≥21)+8 (≥15)
Found down at symptom onset +3
mRS (perstroke) +2 (2–5)+2 (≥3)
GCS +3 (3–8) +2 (9–12)
+5 (3–8)
WBC (×109/L) +3 (>11)
Systolic blood pressure (within 24 h after admission) +2 (>200 mmHg)
OCSP (TACI/POCI) +2
Admission glucose (mmol/L) +2 (≥11.1)
Total score0–100–210–350–50–120–27

Main pathogenic microorganism (35–37)_

Early-Onset SAPLate-Onset SAP
Staphylococcus aureusStaphylococcus aureus
Streptococcal pneumoniaeStreptococcal pneumoniae
Haemophilus influenzaeEnterobacter cloacae
Moraxella catarrhalisEscherichia coli
Klebsiella pneumoniae
Pseudomonas aeruginosa
Acinetobacter baumannii
DOI: https://doi.org/10.2478/pneum-2025-0018 | Journal eISSN: 2247-059X | Journal ISSN: 2067-2993
Language: English
Page range: 122 - 131
Published on: Aug 20, 2025
In partnership with: Paradigm Publishing Services
Publication frequency: Volume open

© 2025 Felicia Grizelda Suryatenggara, Eva Lydia Munthe, published by Romanian Society of Pneumology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.