Severity of oxygen desaturation in OSA–COPD overlap syndrome compared to OSA alone: an observational cohort study

Bianca Stepan; Loredana Cservid; Oana Raduna; Roxana Pleava; Costela Serban; Carmen Ardelean; Stefan Mihaicuta; Stefan Frent

doi:10.2478/pneum-2023-0017

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Severity of oxygen desaturation in OSA–COPD overlap syndrome compared to OSA alone: an observational cohort study

Pneumologia

Volume 71 (2022): Issue 1 (June 2022)

By: Bianca Stepan, Loredana Cservid, Oana Raduna, Roxana Pleava, Costela Serban, Carmen Ardelean, Stefan Mihaicuta and Stefan Frent

Open Access

|Jun 2023

Abstract

Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) syndrome (OSAS) are both common conditions. Their comorbid association – overlap syndrome (OVS) – can result in clinically important nocturnal oxygen desaturation. We sought to compare demographic and anthropometric characteristics, associated comorbidities and oxygen saturation in patients with OVS versus OSA alone.

Methods

We included consecutive patients diagnosed with OSA in our sleep laboratory. Overnight sleep studies were performed, and data regarding demographic and anthropometric characteristics, prevalence of comorbidities and somnographic parameters were compared for patients with OVS versus OSA alone. A P value of <0.05 was considered significant.

Results

A total of 2173 OSA patients were assessed, of whom 381 (17.5%) had OVS. Significant differences were found between the OVS and OSA groups regarding all evaluated demographic and anthropometric characteristics, prevalence of comorbidities and somnographic parameters.

Conclusions

OVS patients were older, were predominantly male, had a higher prevalence of common cardiovascular and metabolic comorbidities, and had worse apnoea–hypopnoea index (AHI) and oxygen saturation parameters.

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Articles in this issue

DOI: https://doi.org/10.2478/pneum-2023-0017 | Journal eISSN: 2247-059X | Journal ISSN: 2067-2993

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Language: English

Page range: 22 - 27

Published on: Jun 28, 2023

Published by: Romanian Society of Pneumology

In partnership with: Paradigm Publishing Services

Publication frequency: Volume open

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Clinical medicine, other,

Internal medicine,

Pneumology

© 2023 Bianca Stepan, Loredana Cservid, Oana Raduna, Roxana Pleava, Costela Serban, Carmen Ardelean, Stefan Mihaicuta, Stefan Frent, published by Romanian Society of Pneumology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 71 (2022): Issue 1 (June 2022)