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Sleep apnoea syndrome in patients with chronic obstructive pulmonary disease and obesity – hypoxic load, comorbidities Cover

Sleep apnoea syndrome in patients with chronic obstructive pulmonary disease and obesity – hypoxic load, comorbidities

Open Access
|Jun 2023

Abstract

Introduction

We analyse anthropometric, somnopolygraphic and comorbidities data in patients with OSA syndrome, OSA with COPD, and OSA with COPD and obesity.

Material and method

2644 OSA patients, three groups: I – OSA (2112 pts., 79.9%); II – OSA and COPD (116 pts., 4.4%); III – OSA, COPD and obesity (416 pts., 15.7%).

Results

significantly older (p < 0.01, p = 001, p < 0.01); more men: 68.4% vs. 80.2% vs. 78.8%; smokers 59.4% vs. 70.7% vs. 74.3%; larger neck circumference: 42.74 ± 5.08 cm vs. 40.57 ± 3.97 cm vs. 45.90 ± 4.92 cm; higher BMI; lower O2 saturation: p < 0.01, p= 123, P < 0.01; higher desaturation index: 30.65 ± 26.96 vs. 18.94 ± 20.28 vs. 42.28 ± 29.02; lowest O2 saturation: (p < 0.01 0, p = 024, p< 0.01); higher AHI: p= 0.001, p < 0.01, p < 0.01; coronary artery disease: p < 0.01, p = 195, p < 0.01; heart failure: p < 0.01, p = 760, p < 0.01; arrhythmias: p < 0.01, p = 796, P < 0.01; stroke: unsignificant; diabetes mellitus: p = 0.252, p = 0.007, p = 0.794; systemic hypertension: p < 0.01, p = 0.786, p < 0.01.

Conclusion

COPD in OSA is more severe, with more diabetes and longer hypertension duration, but not significantly different for O2 saturation, CAD, heart failure, arrhythmia, stroke and systemic hypertension. Obesity adds to overlap OSA–COPD significant burden for all recorded data, with the exception of stroke and diabetes.

DOI: https://doi.org/10.2478/pneum-2023-0012 | Journal eISSN: 2247-059X | Journal ISSN: 2067-2993
Language: English
Page range: 8 - 13
Published on: Jun 28, 2023
Published by: Romanian Society of Pneumology
In partnership with: Paradigm Publishing Services
Publication frequency: Volume open

© 2023 Vlad Stupar, Dragnea M. Virginia-Mihaela, Alina Popa, Loredana Gligor, Andrei Raul Manzur, Romina Birza, Mihai Ardelean, Stefan Mihaicuta, published by Romanian Society of Pneumology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.