Skip to main content
Have a personal or library account? Click to login
Changes in the lipid composition and bioactive compounds of walnut (Juglans regia) under different storage conditions: implications for future research on polycystic ovary syndrome (PCOS) Cover

Changes in the lipid composition and bioactive compounds of walnut (Juglans regia) under different storage conditions: implications for future research on polycystic ovary syndrome (PCOS)

Open Access
|Jul 2026

References

  1. Ahad T, Gull A, Nissar J, Masoodi L, Rather AH. Effect of storage temperatures, packaging materials and storage periods on antioxidant activity and non-enzymatic browning of anti-oxidant treated walnut kernels. Journal of Food Science and Technology. 2020;57(10). doi:10.1007/s13197-020-04387-5
  2. Elouafy Y, El Idrissi ZL, El Yadini A, Harhar H, Alshahrani MM, AL Awadh AA, Goh KW, Ming LC, Bouyahya A, Tabyaoui M. Variations in Antioxidant Capacity, Oxidative Stability, and Physicochemical Quality Parameters of Walnut (Juglans regia) Oil with Roasting and Accelerated Storage Conditions. Molecules. 2022;27(22). doi:10.3390/molecules27227693
  3. Harayama T, Shimizu T. Roles of polyunsaturated fatty acids, from mediators to membranes. Journal of Lipid Research. 2020;61(8). doi:10.1194/JLR.R120000800
  4. Chung MY, Kim BH. Fatty acids and epigenetics in health and diseases. Food Science and Biotechnology. 2024;33(14). doi:10.1007/s10068-024-01664-3
  5. Ampofo J, Grilo FS, Langstaff S, Wang SC. Oxidative Stability of Walnut Kernel and Oil: Chemical Compositions and Sensory Aroma Compounds. Foods. 2022;11(19). doi:10.3390/foods11193151
  6. Bhardwaj A, Singh A, Patnaik RS, Bhardwaj S. Juglans Regia L: A Review of its Traditional Uses Phytochemistry and Therapeutic Applications. Journal of Pharmaceutical Negative Results. 2023;14(1).
  7. Temizyürek F, Gündeşli MA, Canbay Y, Özatar HO, Gölcü E, Altun VC, Atagül Ö, Güney M, Kafkas E, Ugur R, Sütyemez M. Evaluation of biochemical profiles in walnut (Juglans regia L.) genotypes and predictive modeling using advanced machine learning algorithms. European Food Research and Technology. 2025;251(10). doi:10.1007/s00217-025-04826-7
  8. Yurdunuseven Yildiz A, Karaca H. The protective role of shell, packaging technique and storage temperature in lipid oxidation in walnuts of different varieties. Postharvest Biology and Technology. 2024;210. doi:10.1016/j.postharvbio.2023.112747
  9. Cui M, Mo R, Li Q, Wang R, Shen D, Tang F, Liu Y. Maturation-induced changes in phenolic forms and their antioxidant activities of walnuts: A dual view from kernel and pellicle. Food Chemistry: X. 2024;23. doi:10.1016/j.fochx.2024.101792
  10. Ma Y, Wang C, Liu C, Tan J, Ma H, Wang J. Physiochemical responses of the kernel quality, total phenols and antioxidant enzymes of walnut in different forms to the low-temperature storage. Foods. 2021;10(9). doi:10.3390/foods10092027
  11. Verde A, Míguez JM, Leao-Martins JM, Gago-Martínez A, Gallardo M. Melatonin content in walnuts and other commercial nuts. Influence of cultivar, ripening and processing (roasting). Journal of Food Composition and Analysis. 2022;105. doi:10.1016/j.jfca.2021.104180
  12. Albardan L, Platat C, Kalupahana NS. Role of Omega-3 Fatty Acids in Improving Metabolic Dysfunctions in Polycystic Ovary Syndrome. Nutrients. 2024;16(17). doi:10.3390/nu16172961
  13. D. Prabhu Y, Valsala Gopalakrishnan A. Can polyunsaturated fatty acids regulate Polycystic Ovary Syndrome via TGF-β signalling? Life Sciences. 2021;276. doi:10.1016/j.lfs.2021.119416
  14. Zehravi M, Maqbool M, Ara I. Healthy Lifestyle and Dietary Approaches to Treating Polycystic Ovary Syndrome: A Review. Open Health. 2022;3(1). doi:10.1515/openhe-2022-0008
  15. Petrović-Oggiano G, Debeljak-Martačić J, Ranković S, Pokimica B, Mirić A, Glibetić M, Popović T. The effect of walnut consumption on n-3 fatty acid profile of healthy people living in a non-mediterranean west balkan country, a small scale randomized study. Nutrients. 2020;12(1). doi:10.3390/nu12010192
  16. Hajam YA, Rather HA, Neelam, Kumar R, Basheer M, Reshi MS. A review on critical appraisal and pathogenesis of polycystic ovarian syndrome. Endocrine and Metabolic Science. 2024;14. doi:10.1016/j.endmts.2024.100162
  17. Wang J, Zhang K, Sheng J, Ren H, Gong J, Wang Y, Pan D, Wang X, Hao Y. Investigation on Walnut Kernel Oil Extraction Using Different Methods. BioResources. 2023;18(1). doi:10.15376/biores.18.1.869-883
  18. American Oil Chemists’ Society. Official Method Ce 2-66: Preparation of Methyl Esters of Fatty Acids [Official Method] [Internet]. Champaign, IL: AOCS Press; 1997. (Official Methods and Recommended Practices of the AOCS). Official Method Ce 2-66. Elérhető: https://library.aocs.org/Ce-2-66/2
  19. Masoodi L, Gani A, Sircar D, Jan K. Quality analysis of walnut oil extracted by cold press and solvent methods for in vitro phytochemicals, antioxidant activity and GC-MS analysis. Measurement: Food. 2025;18:100223. doi:10.1016/j.meafoo.2025.100223
  20. Laczkó-Zöld E, Komlósi A, Ülkei T, Fogarasi E, Croitoru M, Fülöp I, Domokos E, Ştefănescu R, Varga E. Extractability of polyphenols from black currant, red currant and gooseberry and their antioxidant activity. Acta Biologica Hungarica. 2018. június;69(2):156-69. doi:10.1556/018.69.2018.2.5
  21. Council of Europe. European Pharmacopoeia, section 2.3.2. Identification of fatty oils by thin-layer chromatography. 11. kiad. Strasbourg; 2022.
  22. Iordanescu OA, Radulov I, Buhan IP, Cocan I, Berbecea AA, Popescu I, Posta DS, Camen D, Lalescu D. Physical, nutritional and functional properties of walnuts genotypes (Juglans regia l.) from romania. Agronomy. 2021;11(6). doi:10.3390/agronomy11061092
  23. Ahmadi AR, Shirani F, Abiri B, Siavash M, Haghighi S, Akbari M. Impact of omega-3 fatty acids supplementation on the gene expression of peroxisome proliferator activated receptors-γ, α and fibroblast growth factor-21 serum levels in patients with various presentation of metabolic conditions: a GRADE assessed systematic review and dose-response meta-analysis of clinical trials. Frontiers in Nutrition. 2023;10. doi:10.3389/fnut.2023.1202688
  24. Elmore JS, Nisyrios I, Mottram DS. Analysis of the headspace aroma compounds of walnuts (Juglans regia L.). Flavour Fragr J. 2005. szeptember;20(5):501-6. doi:10.1002/ffj.1477
  25. Garcia-Mendoza M del P, Espinosa-Pardo FA, Savoire R, Etchegoyen C, Harscoat-Schiavo C, Subra-Paternault P. Recovery and antioxidant activity of phenolic compounds extracted from walnut press-cake using various methods and conditions. Industrial Crops and Products. 2021. szeptember;167:113546. doi:10.1016/j.indcrop.2021.113546
  26. Zhou X, Gong X, Li X, An N, He J, Zhou X, Zhao C. The Antioxidant Activities In Vitro and In Vivo and Extraction Conditions Optimization of Defatted Walnut Kernel Extract. Foods. 2023. szeptember 14.;12(18):3417. doi:10.3390/foods12183417
  27. Arcan I, Yemeniciolu A. Antioxidant activity and phenolic content of fresh and dry nuts with or without the seed coat. Journal of Food Composition and Analysis. 2009;22(3). doi:10.1016/j.jfca.2008.10.016
  28. Yan S, Wang X, Yang C, Wang J, Wang Y, Wu B, Qiao L, Zhao J, Mohammad P, Zheng X, Xu J, Zhi H, Zheng J. Insights Into Walnut Lipid Metabolism From Metabolome and Transcriptome Analysis. Frontiers in Genetics. 2021;12. doi:10.3389/fgene.2021.715731
  29. Thiyagarajan DK, Basit H, Jeanmonod R. Physiology, Menstrual Cycle. StatPearls. 2024
DOI: https://doi.org/10.2478/orvtudert-2026-0009 | Journal eISSN: 2537-5059 | Journal ISSN: 1453-0953
Language: English
Page range: 125 - 146
Published on: Jul 11, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year

© 2026 Dalma Máté, Szende Vancea, Elek Ferencz, Eszter Laczkó-Zöld, published by Transylvanian Museum Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.