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Sub-cellular elemental imaging of human muscle tissues affected by neuromuscular diseases Cover

Sub-cellular elemental imaging of human muscle tissues affected by neuromuscular diseases

Nukleonika
Volume 66 (2021): Issue 4 (December 2021)
By: Patrycja Śliż-SzpytmaORCID,  Marek LankoszORCID,  Joanna DudałaORCID,  Dariusz AdamekORCID,  Edyta Radwanska,  Borys KwintaORCID,  Milko JakšićORCID,  Iva Božičević MihalićORCID and  Georgios Provatas  
Open Access
|Nov 2021

Figures & Tables

Fig. 1

View of the measuring chamber.
View of the measuring chamber.

Fig. 2

Optical microscope photo with superimposed STIM image. The red rectangles on the image represent the scan areas of point measurements for control sample.
Optical microscope photo with superimposed STIM image. The red rectangles on the image represent the scan areas of point measurements for control sample.

Fig. 3

Element distribution maps of control sample made with the PIXE method.
Element distribution maps of control sample made with the PIXE method.

Fig. 4

Maps of the elemental distribution of point no. 1 located on control sample.
Maps of the elemental distribution of point no. 1 located on control sample.

Fig. 5

Optical microscope photo with superimposed STIM image. The red rectangles on the image represent the scan areas of point measurements for dystrophy sample.
Optical microscope photo with superimposed STIM image. The red rectangles on the image represent the scan areas of point measurements for dystrophy sample.

Fig. 6

Element distribution maps of dystrophy sample made with the PIXE method.
Element distribution maps of dystrophy sample made with the PIXE method.

Fig. 7

Selected maps of the elemental distribution for point no. 3 – dystrophy sample.
Selected maps of the elemental distribution for point no. 3 – dystrophy sample.

Fig. 8

Box-and-whisker plots for the Kruskal–Wallis test for individual elements with mean values (inner box), means ± standard error (outer box), and means ± standard deviation (whiskers).
Box-and-whisker plots for the Kruskal–Wallis test for individual elements with mean values (inner box), means ± standard error (outer box), and means ± standard deviation (whiskers).

Fig. 9

A graph of the configuration of points representing three types of muscle tissue samples in a layout determined by discriminant variables (axes).
A graph of the configuration of points representing three types of muscle tissue samples in a layout determined by discriminant variables (axes).

Partial Wilks’ lambda values

Partial Wilks’ lambda
KSNaClPMgZnFeBr
0.240.700.950.590.650.930.990.990.99
DOI: https://doi.org/10.2478/nuka-2021-0024 | Journal eISSN: 1508-5791 | Journal ISSN: 0029-5922
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Language: English
Page range: 159 - 164
Submitted on: Dec 29, 2020
Accepted on: Mar 12, 2021
Published on: Nov 25, 2021
Published by: Institute of Nuclear Chemistry and Technology
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
Dystrophy,
Elemental analysis,
Myopathy,
Neurodegenerative diseases,
PIXE
Related subjects:
Chemistry,
Nuclear chemistry,
Physics,
Astronomy and astrophysics,
Physics, other

© 2021 Patrycja Śliż-Szpytma, Marek Lankosz, Joanna Dudała, Dariusz Adamek, Edyta Radwanska, Borys Kwinta, Milko Jakšić, Iva Božičević Mihalić, Georgios Provatas, published by Institute of Nuclear Chemistry and Technology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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