Figure 1
SEM images of nicaraven-loaded and nicaraven-free gelatin nanofibers.
Figure 2
SEM images of NICGELCOL and GELCOL sponges.
Figure 3
MTT assay with L929 cells cultured on NICGELCOL and GELCOL scaffolds during 5 days of culture on the scaffolds.
Figure 4
Swelling properties of NICGELCOL and GELCOL sponges incubated in PBS for 24 h.
Figure 5
MTT assay with L929 cells cultured with 1% H2O2 and NICGELCOL and GELCOL sponges. * shows p-value <0.05.
Figure 6
Radical scavenging activity of NICGELCOL and GELCOL sponges compared with ascorbic acid as the control group.
Figure 7
In vitro wound closure with L929 cells cultured with NICGELCOL and GELCOL sponges on days 1 and 2. * shows p-value <0.05.
Figure 8
In vivo wound closure assay with NICGELCOL and GELCOL sponges in diabetic rats on days 7 and 14 after wounding. * shows p-value <0.05.
Figure 9
Histopathological studies in diabetic wounds treated with NICGELCOL and GELCOL sponges and histomorphometric analysis. * shows p-value <0.05.
Figure 10
ELISA results demonstrating the tissue concentrations of IL6 and TNF-α in wound tissues treated with NICGELCOL and GELCOL sponges. * shows p-value <0.05.