References
- 1. Miroshnikova, M.S. (2021). Study of the potentiated effect of antimicrobial drugs against probiotic strains of microorganisms. Izvestia Orenburg State Agrarian University 2(88): 168-173. [in Russian] https://doi.org/10.37670/2073-0853-2021-88-2-168-17310.37670/2073-0853-2021-88-2-168-173
- 2. Vostroilova, G.A., Shakhov, A.G., Shabunin, S.V., Sashnina, L.Yu., Parshin, P.A., Cheskidova, L.V., Kantorovich, Yu.A. (2018). Сorrective influence of hentabiferon-С on the immune status of post-weaned piglets snd its rffectiveness in the prevention of intestinal infections. Russ Agric Sci. 6, 58-61.
- 3. Cheskidova, L.V., Briukhova, I.V., Grigoreva, N.A. (2019). Advanced research directions of creation of new generation medicines for animals with application of biotechnologies (Review). Bulletin Vet Pharmacol. 2(7): 29-38. [in Russian] https://doi.org/10.17238/issn2541-8203.2019.2.2910.17238/issn2541-8203.2019.2.29
- 4. Mironov, A.N., Bunatyan, N.D., Vasil’ev, A.N., Verstakova, O.L., Zhuravleva, M.V., Lepahin, V.K., Korobov, N.V., et al. (2012). Guidelines for conducting preclinical studies of drugs. Part one. p. 944. Moscow, Russia: Grief and K
- 5. Engalycheva, G.N., Syubaev, R.D., Goryachev, D.V. (2019). Quality standards of preclinical pharmacological studies. The Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products 9(4): 248-255. https://doi.org/10.30895/1991-2919-2019-9-4-248-25510.30895/1991-2919-2019-9-4-248-255
- 6. Parlakpinar, H., Tasdemir, S., Polat, A., Bay-Karabulut, A., Vardi, N., Ucar, M., Yanilmaz, M., Kavakli, A., Acet, A. (2006). Protective effect of chelerythrine on gentamicin-induced nephrotoxicity. Cell Biochem Funct. 24(1):41-48. https://doi.org/10.1002/cbf.1182 PMid:1558409110.1002/cbf.1182
- 7. Gozhenko, A.I., Vladimirova, M.P., Topor, E.A. (2005). Renal dysfunctions in white rats after a single administration of gentamicin. Nephrology. 9(4): 75-79. [in Russian]
- 8. Hosaka, E.M., Santos, O.F.P., Seguro, A.C., Vattimo, M.F.F. (2004). Effect of cyclooxygenase inhibitors on gentamicin induced nephrotoxicity in rats. Braz J Med Biol Res. 37(7): 979-985. https://doi.org/10.1590/S0100-879X2004000700006 PMid: 1526400410.1590/S0100-879X2004000700006
- 9. Durnev, A.D. (2018). Antimutagenesis and antimutagens. Hum Physiol. 44(3): 116-137. [in Russian] https://doi.org/10.1134/S036211971803005210.1134/S0362119718030052
- 10. Horisberger, M.A., de Staritzky, K. (1987). A recombinant human interferon-alpha B/D hybrid with a broad host-range. J Gen Virol. 68(Pt 3): 945-948. https://doi.org/10.1099/0022-1317-68-3-945 PMid:302931510.1099/0022-1317-68-3-945
- 11. Martal, J.L., Chêne, N.M., Huynh, L.P., L’Haridon, R.M., Reinaud, P.B., Guillomot, M.W., Charlier, M.A., Charpigny, S.Y. (1998). IFN-tau: a novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities. Biochimie 80(8-9): 755-777. https://doi.org/10.1016/S0300-9084(99)80029-710.1016/S0300-9084(99)80029-7
- 12. Blankenstein, T., Qin, Z. (2003). The role of IFN-gamma in tumor transplantation immunity and inhibition of chemical carcinogenesis. Curr Opin Immunol. 15(2): 148-154. https://doi.org/10.1016/S0952-7915(03)00007-410.1016/S0952-7915(03)00007-4
- 13. Makedonov, G.P., Chekova, V.V., Yakubovskaya, E.L., Zasukhina, G.D. (1990). Modification of DNA repair by human interferons. Acta Biol Hung. 41(1-3): 187-197.
- 14. Kumari, S., Naik, P., Vishma, B.L., Salian, S.R., Devkar, R.A., Khan, S., Mutalik, S., Kalthur, G., Adiga, S.K. (2016). Mitigating effect of Indian propolis against mitomycin C induced bone marrow toxicity. Cytotechnology 68(5): 1789-1800. https://doi.org/10.1007/s10616-015-9931-4 PMid:26590833 PMCid:PMC502355210.1007/s10616-015-9931-4502355226590833
- 15. Sinitsky, M.Y., Kutikhin, A.G., Tsepokina, A.V., Shishkova, D.K., Asanov, M.A., Yuzhalin, A.E., Minina, V.I., Ponasenko, A.V. (2020). Mitomycin C induced genotoxic stress in endothelial cells is associated with differential expression of proinflammatory cytokines. Mutat Res Genet Toxicol Environ Mutagen. 858-860: 503252. https://doi.org/10.1016/j.mrgentox.2020.503252 PMid:3319893310.1016/j.mrgentox.2020.50325233198933
- 16. Hayashi, M. (2016). The micronucleus test-most widely used in vivo genotoxicity test. Genes Environ. 38, 18. https://doi.org/10.1186/s41021-016-0044-x PMid:27733885 PMCid:PMC504562510.1186/s41021-016-0044-x504562527733885
- 17. Agarwal, D.K., Chauhan, L.K. (1993). An improved chemical substitute for fetal calf serum for the micronucleus test. Biotech Histochem. 68(4): 187-188. https://doi.org/10.3109/10520299309104695 PMid:821857010.3109/105202993091046958218570
- 18. The European agency for the evaluation of medicinal products, veterinary medicines and inspections (2001). Committee for veterinary medicinal products. Gentamicin summary report. EMEA/MRL/803/01-FINAL. November 2001. 1-9. https://www.ema.europa.eu/en/documents/mrl-report/gentamicin-summary-report-3-committee-veterinary-medicinal-products_en.pdf
- 19. El-Ashmawy, I.M., El-Nahas, A.F., Salama, O.M. (2006). Grape seed extract prevents gentamicin-induced nephrotoxicity and genotoxicity in bone marrow cells of mice. Basic Clin Pharmacol Toxicol. 99(3): 230-236. https://doi.org/10.1111/j.1742-7843.2006.pto_497.x PMid:1693029610.1111/j.1742-7843.2006.pto_497.x16930296
- 20. Velasco-Velázquez, M.A., Maldonado, P.D., Barrera, D., Torres, V., Zentella-Dehesa, A., Pedraza-Chaverrí, J. (2006). Aged garlic extract induces proliferation and ameliorates gentamicin-induced toxicity in LLC-PK1 cells. Phytother Res. 20(1): 76-78. https://doi.org/10.1002/ptr.1780 PMid:1639784810.1002/ptr.178016397848
- 21. Martínez-Salgado, C., Eleno, N., Tavares, P., Rodríguez-Barbero, A., García-Criado, J., Bolaños, J.P., López-Novoa, J.M. (2002). Involvement of reactive oxygen species on gentamicin-induced mesangial cell activation. Kidney Int. 62(5): 1682-1692. https://doi.org/10.1046/j.1523-1755.2002.00635.x PMid:1237196810.1046/j.1523-1755.2002.00635.x12371968
- 22. Bustos, P.S., Deza-Ponzio, R., Páez, P.L., Albesa, I., Cabrera, J.L., Virgolini, M.B., Ortega, M.G. (2016). Protective effect of quercetin in gentamicin-induced oxidative stress in vitro and in vivo in blood cells. Effect on gentamicin antimicrobial activity. Environ Toxicol Pharmacol. 48, 253-264. https://doi.org/10.1016/j.etap.2016.11.004 PMid:2784640810.1016/j.etap.2016.11.00427846408
- 23. Kim, J., Lee, Y., Koh, W.S., Kim, C., Choi, I.Y., Kwon, S.C., Lee, G.S., Han, J.Y., Lee, M. (2007). Genotoxicity assessment of HM10620 containing recombinant human interferon-alpha. Drug Chem Toxicol. 30(1): 83-95. https://doi.org/10.1080/01480540601017744 PMid:1736486610.1080/0148054060101774417364866
- 24. Bidgoli, S.A., Heshmati, M., Keyhan, H., Afshary, A. (2012). Genotoxicity assessment of recombinant human interferon gamma in human lymphocytes. JAASP 1(2):107-115.
- 25. Tsoncheva, V.L., Todorova, K.A., Ivanov I.G., Maximova, V.A. (2008). Influence of interferons on the repair of UV-damaged DNA. Z Naturforsch C J Biosci. 63(3-4): 303-307. https://doi.org/10.1515/znc-2008-3-423 PMid:1853347810.1515/znc-2008-3-42318533478
- 26. Hara, T., Koyama, K., Miyazaki, H., Ohguro, Y., Shimizu, M. (1977). Safety evaluation of KW-1062. I. Acute toxicity in mice, rats and dogs, subacute and chronic toxicity in rats (author’s transl). Jpn J Antibiot. 30(6): 386-407.
- 27. Steinbach, T.J., Patrick, D.J., Cosenza, M.E. (2019). Toxicologic pathology for non-pathologists. New York: Springer; Humana https://doi.org/10.1007/978-1-4939-9777-010.1007/978-1-4939-9777-0
- 28. Haitov, R.M., Ataullahanov, R.I., Allenov, S.N., Alyaev, Y.U.G., Balabolkin, I.I., Batkaev, E.A., Batkaeva, N.V., et al. (2014). Immunotherapy: a guide for physicians. Moskow: GEOTAR-Media [in Russian]
- 29. Selleri, C., Sato, T., Anderson, S., Young, N.S., Maciejewski, J.P. (1995). Interferon-gamma and tumor necrosis factor-alpha suppress both early and late stages of hematopoiesis and induce programmed cell death. J Cell Physiol. 165(3): 538-546. https://doi.org/10.1002/jcp.1041650312 PMid:759323310.1002/jcp.10416503127593233
- 30. Lin, F., Karwan, M., Saleh, B., Hodge, D.L., Chan, T., Boelte, K.C., Keller, J.R., Young, H.A. (2014). IFN-γ causes aplastic anemia by altering hematopoietic stem/progenitor cell composition and disrupting lineage differentiation. Blood 124(25): 3699-3708. https://doi.org/10.1182/blood-2014-01-549527 PMid:25342713 PMCid:PMC426398010.1182/blood-2014-01-549527426398025342713
- 31. Schroder, K., Hertzog, P.J., Ravasi, T., Hume, D.A. (2004). Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol. 75(2): 163-189. https://doi.org/10.1189/jlb.0603252 PMid:1452596710.1189/jlb.060325214525967
- 32. Murayama, T., Takahashi, N., Ikoma, N. (1996). Cytotoxicity and characteristics of mitomycin C. Ophthalmic Res. 28(3): 153-159. https://doi.org/10.1159/000267896 PMid:882917110.1159/0002678968829171
- 33. Pawlik, T.M., Keyomarsi, K. (2004). Role of cell cycle in mediating sensitivity to radiotherapy. Int J Radiat Oncol Biol Phys. 59(4): 928-942. https://doi.org/10.1016/j.ijrobp.2004.03.005 PMid:1523402610.1016/j.ijrobp.2004.03.00515234026
- 34. Fingert, H.J., Chang, J.D., Pardee, A.B. (1986). Cytotoxic, cell cycle, and chromosomal effects of methylxanthines in human tumor cells treated with alkylating agents. Cancer Res. 46(5): 2463-2467.
- 35. Wang, X.Y., Crowston, J.G., Zoellner, H., Healey, P.R. (2007). Interferon-alpha and interferon-gamma sensitize human tenon fibroblasts to mitomycin-C. Invest Ophthalmol Vis Sci. 48(8): 3655-3661. https://doi.org/10.1167/iovs.06-1121 PMid:1765273510.1167/iovs.06-112117652735