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Development and physicochemical evaluation of a gelatine-based hydrogel tube for potential use in veterinary glaucoma implants Cover

Development and physicochemical evaluation of a gelatine-based hydrogel tube for potential use in veterinary glaucoma implants

Open Access
|Mar 2026

References

  1. Bar-David L., Blumenthal E.Z.: Evolution of glaucoma surgery in the last 25 years. Rambam Maimonides Med J 2018, 30, 9, e0024, doi: 10.5041/RMMJ.10345.
  2. Boral S., Gupta A.N., Bohidar H.B.: Swelling and de-swelling kinetics of gelatin hydrogels in ethanol-water marginal solvent. Int J Biol Macromol 2006, 15, 240–249, doi: 10.1016/j.ijbiomac.2006.03.028.
  3. Cady S.M., Cheifetz P.M., Galeska I.: Chapter 12, Veterinary Long-Acting Injections and Implants. In: Long Acting Animal Health Drug Products: Fundamentals and Applications, edited by M.J. Rathbone, A. McDowell. Springer, New York, NY, USA, 2013, pp. 271–294, doi: 10.1007/978-1-4614-4439-8_12.
  4. Cui T., Sun Y., Wu Y., Wang J., Ding Y., Cheng J., Guo M.: Mechanical, microstructural, and rheological characterization of gelatin-dialdehyde starch hydrogels constructed by dual dynamic crosslinking. LWT 2022, 161, 113374, doi: 10.1016/j.lwt.2022.113374.
  5. Desai S.J., Pumphrey S.A., Koethe B.: Comparative effects of latanoprost and latanoprostene bunod on intraocular pressure and pupil size in ophthalmologically normal Beagle dogs. Vet Ophthalmol 2022, 25, 282–290, doi: 10.1111/vop.12982.
  6. Dixon M.W., Moulin T.A., Margolis M.S., Palko J.R., Mortensen P., Conner I.P., Sheybani A.: Comparative outcomes of the Molteno3 and Baerveldt glaucoma implants. Ophthalmol Glaucoma 2020, 3, 40–50, doi: 10.1016/j.ogla.2019.10.003.
  7. Fea A.M., Novarese C., Caselgrandi P., Boscia G.: Glaucoma treatment and hydrogel: current insights and state of the art. Gels 2022, 8, 510, doi: 10.3390/gels8080510.
  8. Gelatt K.N., MacKay E.O.: Effect of different dose schedules of travoprost on intraocular pressure and pupil size in the glaucomatous Beagle. Vet Ophthalmol 2004, 7, 53–57, doi: 10.1111/j.1463-5224.2004.00326.x.
  9. Gun’ko V.M., Savina I.N., Mikhalovsky S.V.: Properties of water bound in hydrogels. Gels 2017, 3, 37, doi: 10.3390/gels3040037.
  10. Hampson E.C.G.M., Smith R.I.E., Bernays M.E.: Primary glaucoma in Burmese cats. Aust Vet J 2002, 80, 672–680, doi: 10.1111/j.1751-0813.2002.tb11292.x.
  11. Johnsen D.A.J., Maggs D.J., Kass P.H.: Evaluation of risk factors for development of secondary glaucoma in dogs: 156 cases (1999– 2004). J Am Vet Med Assoc 2006, 229, 1270–1274, doi: 10.2460/javma.229.8.1270.
  12. Karimi A., Navidbakhsh M.: Material properties in unconfined compression of gelatin hydrogel for skin tissue engineering applications. Biomed Tech 2014, 59, 479–486, doi: 10.1515/bmt-2014-0028.
  13. Komáromy A.M., Koehl K.L., Park S.A.: Looking into the future: gene and cell therapies for glaucoma. Vet Ophthalmol 2021, 24, 16–33, doi: 10.1111/vop.12858.
  14. Lv B., Bu X., Da Y., Duan P., Wang H., Ren J., Lyu B., Gao D., Ma J.: Gelatin/PAM double network hydrogels with super-compressibility. Polymer 2020, 210, 123021, doi: 10.1016/j.polymer.2020.123021.
  15. Maggs D.J., Miller P.E., Ofri R.: Slatter’s Fundamentals of Veterinary Ophthalmology, fourth edition. Saunders, Philadelphia, PA, USA, 2007.
  16. Manish V., Arockiarajan A., Tamadapu G.: Synthesis, characterization, and modeling of gelatin-based magnetic hydrogel beams. Eur J Mech A Solids 2024, 106, 105292, doi: 10.1016/j.euromechsol.2024.105292.
  17. Maślanka T.: A review of the pharmacology of carbonic anhydrase inhibitors for the treatment of glaucoma in dogs and cats. Vet J 2015, 203, 278–284, doi: 10.1016/j.tvjl.2014.12.017.
  18. McLellan G.J., Teixeira L.B.C.: Feline glaucoma. Vet Clin North Am Small Anim Pract 2015, 45, 1307–1333, doi: 10.1016/j.cvsm.2015.06.010.
  19. Pal K., Banerjee I.: Polymeric Gels: Characterization, Properties and Biomedical Applications. Woodhead Publishing, Duxford, UK, 2018.
  20. Sharun K., Banu S.A., Alifsha B., Abualigah L., Pawde A.M., Dhama K., Pal A.: Mesenchymal stem cell therapy in veterinary ophthalmology: clinical evidence and prospects. Vet Res Commun 2024, 48, 3517–3531, doi: 10.1007/s11259-024-10522-w.
  21. Telle M.R., Chen N., Shinsako D., Kiland J.A., Oikawa K., Møller Trane R., McLellan G.J.: Relationship between corneal sensitivity, corneal thickness, corneal diameter, and intraocular pressure in normal cats and cats with congenital glaucoma. Vet Ophthalmol 2019, 22, 4–12, doi: 10.1111/vop.12558.
  22. Torbicz W., Błażewicz S., Marciniak J.: Inżyneria Biomediczna Podstawy i Zastostowania, Tom 4, Biomateriały (Fundamentals and Applications of Biomedical Engineering, Volume 4, Biomaterials – in Polish). Akademicka Oficyna Wydawnicza Exit, Warsaw, Poland, 2016.
  23. Wang S., Li K., Zhou Q.: High strength and low swelling composite hydrogels from gelatin and delignified wood. Sci Rep 2020, 10, 17842, doi: 10.1038/s41598-020-74860-w.
  24. Willis A.M., Diehl K.A., Robbin T.E.: Advances in topical glaucoma therapy. Vet Ophthalmol 2002, 5, 9–17, doi: 10.1046/j.1463-5216.2001.00202.x.
  25. van der Woerdt A.: The treatment of acute glaucoma in dogs and cats. J Vet Emerg Crit Care 2001, 11, 199–204, doi: 10.1111/j.1476-4431.2001.tb00084.x
Language: English
Page range: 157 - 168
Submitted on: Jun 26, 2025
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Accepted on: Mar 13, 2026
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Published on: Mar 19, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Piotr Szatkowski, Martyna Fröhlich, Oliwia Grałek, Magdalena Tabor, Edyta Molik, Zuzanna Flis, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution 4.0 License.