Surveillance of a PLOD gene variant linked to fragile foal syndrome in Silesian horses in Poland: implications for genetic monitoring and breeding strategies

n	Genotype totals							Genotype frequency		Allele frequency		95% CI range
	Observed	Expected*	Observed	Expected*	Observed	Expected*		Genotype frequency		Allele frequency		95% CI range
	N/N	N/N	N/FFS	N/FFS	FFS/FFS	FFS/FFS	N/N	N/FFS	FFS/FFS	N	FFS
	248		36		0
284							0.8732	0.1268	0	0.9366	0.0634	1.3005
		249.2		33.5		1.3

1* – calculated by chi-squared test for Hardy–Weinberg equilibrium; CI – confidence interval; n – number of analysed horses; N – wild-type allele; FFS – mutant allele

Birth-year breakdown of fragile foal syndrome gene carriage in the analysed Silesian horse population

Pedigree chart showing inheritance of the mutation causing fragile foal syndrome in Polish Silesian horses. Numbers inside shapes are offspring totals

References

Authors

Metrics

Articles in this issue

DOI: https://doi.org/10.2478/jvetres-2025-0060 | Journal eISSN: 2450-8608 (formerly 2300-3235)

Journal RSS Feed

Language: English

Page range: 599 - 602

Submitted on: Mar 17, 2025

Accepted on: Oct 21, 2025

Published on: Oct 27, 2025

Published by: National Veterinary Research Institute in Pulawy

In partnership with: Paradigm Publishing Services

Keywords:

autosomal recessive disease,

equine genetic disorders,

genetic testing,

PCR-RFLP,

single nucleotide polymorphism

Related subjects:

Life sciences,

Molecular biology,

Microbiology and virology,

Life sciences, other,

Medicine,

Veterinary medicine

© 2025 Monika Stefaniuk-Szmukier, Aleksandra Błaszczak, Bogusława Długosz, Adrianna Musiał, Katarzyna Ropka-Molik, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution 4.0 License.

Volume 69 (2025): Issue 4 (December 2025)

Surveillance of a PLOD gene variant linked to fragile foal syndrome in Silesian horses in Poland: implications for genetic monitoring and breeding strategies

Figures & Tables

Table 1.

Fig. 1.

Fig. 2.

Paradigm

My account